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| Epidemiological characteristics of hepatitis E in Shaoxing City from 2006 to 2024 |
| LIU Mingqi1, MA Yan1, ZHENG Yingying2, CHEN Haimiao1, LI Jun1, FANG Yirong1
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1. Shaoxing Center for Disease Control and Prevention, Shaoxing, Zhejiang 312000, China;
2. Shangyu District Center for Disease Control and Prevention, Shaoxing, Zhejiang 312300, China |
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Abstract Objective To investigate the epidemiological characteristics of hepatitis E in Shaoxing City, Zhejiang Province from 2006 to 2024, so as to provide the evidence for the prevention and control of hepatitis E. Methods Data on hepatitis E incidence in Shaoxing City from 2006 to 2024 were collected through the Surveillance System of China Information System for Disease Control and Prevention. The epidemiological characteristics were analyzed using descriptive epidemiological methods. The trend in hepatitis E incidence was analyzed using the average annual percent change (AAPC) and annual percent change (APC). The spatial-temporal clustering characteristics of hepatitis E incidence were identified using spatial-temporal scanning analysis. Results A total of 2 408 hepatitis E cases were reported in Shaoxing City from 2006 to 2024, with an average annual reported incidence of 2.55/105. The overall trend was not statistically significant (AAPC=3.181%, P>0.05). Specifically, it showed an upward trend from 2006 to 2011 (APC=17.371%, P<0.05), a downward trend from 2011 to 2019 (APC=-12.497%, P<0.05), and an upward trend from 2019 to 2024 (APC=18.076%, P<0.05). The epidemic season of hepatitis E was from January to May, with seasonal indices of 122.09%, 118.60%, 145.02%, 129.57%, and 106.15%, respectively. The top three average annual reported incidences were identified in Zhuji City, Xinchang County, and Shengzhou City, with rates of 4.18/105, 2.85/105, and 2.74/105, respectively. The average annual reported incidence of hepatitis E was higher in males than in females (3.52/105 vs. 1.56/105, P<0.05). A relatively large number of hepatitis E cases were reported among individuals aged 40-<70 years, with 1 639 cases (68.06%). Among them, the group aged 60-<70 years had the highest average annual reported incidence of hepatitis E, at 4.92/105. Farmers constituted the predominant occupational group, accounting for 1 515 cases (62.92%). Spatial-temporal scanning analysis identified two clusters in Shaoxing City from 2006 to 2024. The class Ⅰ cluster was located in Shengzhou City, with aggregation time from January 1, 2011 to May 1, 2014. The class Ⅱ cluster was located in Xinchang County, with aggregation time from December 1, 2012 to March 31, 2013. Conclusions The reported incidence of hepatitis E in Shaoxing City from 2006 to 2024 exhibited a pattern of an initial increase, followed by a decrease, and then a subsequent rise. The disease demonstrated higher prevalence during the winter and spring seasons. Key populations for targeted control and prevention include males, individuals aged 40-<70 years, and farmers. Shengzhou City and Xinchang County were identified as high-risk areas.
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Received: 18 June 2025
Revised: 19 August 2025
Published: 20 November 2025
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[1] 富小飞,刘砚清,胡洁,等.2005—2021年嘉兴市甲型病毒性肝炎和戊型病毒性肝炎流行特征分析[J].预防医学,2023,35(9):737-740.
FU X F,LIU Y Q,HU J,et al.Epidemiological characteristics of hepatitis A and hepatitis E in Jiaxing City from 2005 to 2021[J].China Prev Med J,2023,35(9):737-740.(in Chinese)
[2] World Health Organization.Hepatitis E[EB/OL].[2025-08-19].https://www.who.int/news-room/fact-sheets/detail/hepatitis-e.
[3] 朱月萍,朱传武.戊型肝炎高风险人群的防治进展[J].临床肝胆病杂志,2023,39(11):2524-2529.
ZHU Y P,ZHU C W.Advances in the prevention and treatment of the high-risk population for hepatitis E[J].J Clin Hepatol,2023,39(11):2524-2529.(in Chinese)
[4] 孙校金,张国民,郑徽,等.2004—2017年中国戊型肝炎流行特征分析[J].中华预防医学杂志,2019,53(4):382-387.
SUN X J,ZHANG G M,ZHENG H,et al.Epidemiological analysis of viral hepatitis E in China,2004-2017[J].Chin J Prev Med,2019,53(4):382-387.(in Chinese)
[5] 唐晓倩,王瑞,张川,等.2008—2023年浙江省戊型肝炎流行特征和时空聚集性研究[J].中华流行病学杂志,2025,46(5):789-795.
TANG X Q,WANG R,ZHANG C,et al.Epidemiological characteristics and spatial-temporal clustering of hepatitis E in Zhejiang Province from 2008 to 2023[J].Chin J Epidemiol,2025,46(5):789-795.(in Chinese)
[6] 叶振锋,周云,蒋述香,等.基于Joinpoint回归模型2012—2023年广西壮族自治区桂林市流行性腮腺炎流行趋势分析[J].疾病监测,2024,39(12):1610-1614.
YE Z F,ZHOU Y,JIANG S X,et al.Joinpoint regression model based analysis on mumps incidence trend in Guilin,Guangxi Zhuang Autonomous Region,2012-2023[J].Dis Surveill,2024,39(12):1610-1614.(in Chinese)
[7] 李克,庞志峰,吴晓虹,等.2005—2023年金华市猩红热流行特征和时空聚集性分析[J].预防医学,2025,37(7):705-709.
LI K,PANG Z F,WU X H,et al.Epidemiological characteristics and spatio-temporal clustering analysis of scarlet fever in Jinhua City from 2005 to 2023[J].China Prev Med J,2025,37(7):705-709.(in Chinese)
[8] 张海荣,林志强,吴瑞红,等.2014—2023年福建省戊型病毒性肝炎流行趋势和时空聚集性[J].中华疾病控制杂志,2024,28(11):1361-1364.
ZHANG H R,LIN Z Q,WU R H,et al.Epidemiological trends and spatiotemporal clustering of hepatitis E in Fujian Province,2014-2023[J].Chin J Dis Control Prev,2024,28(11):1361-1364.(in Chinese)
[9] 中华人民共和国卫生部.戊型病毒性肝炎诊断标准:WS 301—2008[S].北京:人民卫生出版社,2009.
Ministry of Health of the People's Republic of China.Diagnostic criteria for hepatitis E:WS 301—2008[S].Beijing:People's Medical Publishing House,2009.(in Chinese)
[10] 黄澳迪,唐林,王晓琪,等.中国2011—2021年戊型病毒性肝炎发病趋势和时空聚集性[J].中国疫苗和免疫,2022,28(4):417-421.
HUANG A D,TANG L,WANG X Q,et al.Hepatitis E incidence trends and spatial-temporal clustering in China,2011-2021[J].Chin J Vaccines Immun,2022,28(4):417-421.(in Chinese)
[11] TAN J,CHEN Y J,WANG L,et al.Acute sporadic hepatitis E in the Zhejiang coastal area of China:a 14-year hospital-based surveillance study[J/OL].Virol J,2019,16(1)[2025-08-19].https://doi.org/10.1186/s12985-019-1119-7.
[12] 马涛,丁松宁,汪君君,等.2010—2022年南京市戊型病毒性肝炎流行病学特征和空间聚集性[J].中国疫苗和免疫,2023,29(5):539-543.
MA T,DING S N,WANG J J,et al.Epidemiological characteristics and spatial clustering of hepatitis E in Nanjing city from 2010 to 2022[J].Chin J Vaccines Immun,2023,29(5):539-543.(in Chinese)
[13] 钟秀华. 化学发光法与胶体金法检测甲肝、戊肝的临床价值研究[J].中国现代药物应用,2025,19(6):55-58.
ZHONG X H.Study on the clinical value of chemiluminescence and colloidal gold methods for the detection of viral hepatitis A and viral hepatitis E[J].Chin J Mod Drug Appl,2025,19(6):55-58.(in Chinese)
[14] YANG M,CHENG X Q,ZHAO Z Y,et al.Feasibility of controlling hepatitis E in Jiangsu Province,China:a modelling study[J/OL].Infect Dis Poverty,2021,10(1)[2025-08-19].https://doi.org/10.1186/s40249-021-00873-w.
[15] FENG Y,CUI X Y,LYU J J,et al.Deep learning models for hepatitis E incidence prediction leveraging meteorological factors[J].PLoS One,2023,18(3):1-15.
[16] 唐莹,管文齐,王凤双,等.2005—2019年北京市顺义区戊型肝炎流行病学特征及危险因素分析[J].华南预防医学,2021,47(7):926-929.
TANG Y,GUAN W Q,WANG F S,et al.Epidemiological characteristics and risk factors of hepatitis E in Shunyi District of Beijing from 2005 to 2019[J].South China J Prev Med,2021,47(7):926-929.(in Chinese)
[17] 章伟,周印.2013—2022年镇江市戊型病毒性肝炎流行病学特征[J].江苏预防医学,2024,35(5):646-647,650.
ZHANG W,ZHOU Y.Epidemiological characteristics of viral hepatitis E in Zhenjiang City from 2013 to 2022[J].Jiangsu J Prev Med,2024,35(5):646-647,650.(in Chinese) |
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