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预防医学  2022, Vol. 34 Issue (8): 788-793    DOI: 10.19485/j.cnki.issn2096-5087.2022.08.007
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职业性铝暴露对视空间建构能力的影响研究
弓宇娟, 李娟, 张靖琦, 孙宇涵, 何璐阳, 王林平
山西医科大学公共卫生学院,山西 太原 030001
Effect of occupational aluminum exposure on the visuospatialconstruction ability
GONG Yujuan, LI Juan, ZHANG Jingqi, SUN Yuhan, HE Luyang, WANG Linping
School of Public Health, Shanxi Medical University, Taiyuan, Shanxi 030001, China
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摘要 目的 探讨铝作业工人视空间建构能力与铝暴露的关系,为铝作业工人职业损害的早期防护提供依据。方法 采用整群抽样方法抽取山西省某铝厂442名作业工人为调查对象,收集人口学信息和职业史;采用电感耦合等离子体质谱法检测血铝浓度;采用蒙特利尔认知评估量表(MoCA)中文版的复制立方体测试(CCT)评估视空间建构能力;采用多因素logistic回归模型分析视空间建构能力与血铝浓度的关联。结果 调查铝作业工人442人,均为男性,年龄为(43.40±7.31)岁,工龄为(22.64±8.35)年,血铝浓度均值为33.87 µg/L。视空间建构能力受损206人,占46.61%;其中血铝浓度>33.87 µg/L 127人,占61.65%;受教育年限6~<10年190人,占92.23%;电解工118人,占57.28%;轮班114人,占55.34%;睡眠质量很好123人,占59.71%。多因素logistic回归分析结果显示,血铝浓度>33.87 μg/L(OR=2.490,95%CI:1.531~4.052)、受教育年限≥6年(OR:0.075~0.246,95%CI:0.015~0.622)、工种为非电解工(OR=0.838,95%CI:0.425~0.987)、轮班(OR=1.179,95%CI:1.078~1.435)和睡眠质量很好(OR=0.104,95%CI:0.012~0.896)与视空间建构能力受损存在统计学关联。结论 作业工人视空间建构能力受损与铝暴露相关。
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关键词 铝暴露复制立方体视空间建构能力职业损害    
AbstractObjective To examine the correlation between visuospatial construction ability and occupational aluminum exposure among aluminum workers, so as to provide the evidence for early protection of occupational injury among aluminum workers. Methods A total of 442 workers in an aluminum factory in Shanxi Province were selected using a cluster sampling method, and participants' demographic features and occupational history were collected. The blood aluminum concentration was measured using inductively coupled plasma mass spectrometry (ICP-MS), and the visuospatial construction ability was evaluated with the Cube Copying Test (CCT) of the Chinese version of the Montreal Cognitive Assessment (MoCA). The correlation between the visuospatial construction ability and blood aluminum concentration was examined using a multivariable logistic regression model. Results A total of 442 aluminum workers were enrolled, and all participants were male, with a mean age of (43.40±7.31) years, labor service duration of (23.64±8.35) years and a mean blood aluminum concentration of 33.87 µg/L. Of all participants, there were 206 workers with impaired visuospatial construction ability (46.61%), including 127 workers with blood aluminum concentrations of >33.87 µg/L (61.65%); 190 workers with educational duration of 6 to 9 years (92.23%), 118 electrolytic aluminum workers (57.28%), 114 workers with work shifts (55.34%), and 123 workers with a very good sleep quality (59.71%). Multivariable logistic regression analysis revealed that blood aluminum concentrations of >33.87 µg/L (OR=2.490, 95%CI: 1.531-4.052), educational duration of 6 years or more (OR: 0.075-0.246, 95%CI: 0.015-0.622), work type as a non-electrolytic aluminum worker (OR=0.838, 95%CI: 0.425-0.987), work shift (OR=1.179, 95%CI: 1.078-1.435) and a very good sleep quality (OR=0.104, 95%CI: 0.012-0.896) significantly correlated with impaired visuospatial construction ability among aluminum worker. Conclusion Impaired visuospatial construction ability correlates with occupational aluminum exposure among aluminum workers.
Key wordsaluminum exposure    cube copying test    visuospatial construction ability    occupational injury
收稿日期: 2022-04-08      修回日期: 2022-06-14      出版日期: 2022-08-10
中图分类号:  R135  
基金资助:国家自然科学基金项目(81302410); 山西医科大学博士启动基金项目(03201520)
作者简介: 弓宇娟,硕士研究生在读
通信作者: 王林平,E-mail:sxwlp5945@sxmu.edu.cn   
引用本文:   
弓宇娟, 李娟, 张靖琦, 孙宇涵, 何璐阳, 王林平. 职业性铝暴露对视空间建构能力的影响研究[J]. 预防医学, 2022, 34(8): 788-793.
GONG Yujuan, LI Juan, ZHANG Jingqi, SUN Yuhan, HE Luyang, WANG Linping. Effect of occupational aluminum exposure on the visuospatialconstruction ability. Preventive Medicine, 2022, 34(8): 788-793.
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