Serotype and drug resistance of Salmonella from foodborne diseases in Longwan District
ZHOU Shanhui1, HU Yuqin2, ZHENG Qiongqiong1, WANG Xiaohong1, LI Yi2, XIANG Guangxin3
1. Longwan District Center for Disease Control and Prevention (Longwan District Institute of Public Health Supervision), Wenzhou, Zhejiang 325024, China; 2. Wenzhou Center for Disease Control and Prevention (Wenzhou Institute of Public Health Supervision), Wenzhou, Zhejiang 325000, China; 3. School of Laboratory Medicine, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China
Abstract：Objective To analyze the serotypes and drug resistance of Salmonella isolated from food-borne disease surveillance samples in Longwan District, Wenzhou City, Zhejiang Province, so as to provide evidence for the prevention and treatment of Salmonella infection. MethodsSalmonella strains isolated from feces or anal swabs of patients with foodborne diarrhea in Longwan District People's Hospital from 2018 to 2024 were collected. After re-identification, slide agglutination test was used to identify serotypes. The drug susceptibility test of live Salmonella strains was performed using the broth microdilution method, and the resistance patterns were analyzed. Results A total of 2 293 samples were collected, and 186 strains of Salmonella were isolated, with a detection rate of 8.11%. The detection rate was higher from May to October. A total of 28 Salmonella serotypes were identified, with S. typhimurium (72 isolates, 38.71%), S. enteritidis (31 isolates, 16.67%), and S. London (30 isolates, 16.13%) being dominant. Among the 121 Salmonella live strains, 20 strains were susceptible to 14 antibacterial drugs. A total of 101 strains were resistant to antibacterial drugs, and the drug resistance rate was 1.65%-67.77%, with the drug resistance rate of ampicillin being the highest, and the drug resistance rate of imipenem was the lowest. S. typhimurium had the highest resistance rate to tetracycline (78.26%). S. enteritidis had the highest resistance rate to ampicillin (100.00%). S. London had the highest resistance rate to tetracycline (66.67%). Fifty-five types of drug resistance patterns were detected, showing a number of drug resistance of 1-10, of which 76 strains were multi-drug resistant, accounting for 75.25%. The predominant multidrug resistance patterns were ampicillin/sulbactam-cefazolin-ampicillin-nalidixic acid (10.53%), tetracycline-ampicillin-nalidixic acid (9.21%), and ampicillin/sulbactam-ampicillin-nalidixic acid (7.89%). ConclusionsSalmonella strains isolated from foodborne diseases in Longwan District were mainly detected in summer and autumn. S. typhimurium, S. enteritidis, and S. London were the predominant serotypes. The drug resistance of Salmonella to different antibacterial drugs was different, and the drug resistance spectrum showed diversity.
周珊慧, 胡玉琴, 郑琼琼, 王晓红, 李毅, 项光新. 龙湾区食源性疾病沙门菌血清型及耐药性分析[J]. 预防医学, 2025, 37(7): 697-700,704.
ZHOU Shanhui, HU Yuqin, ZHENG Qiongqiong, WANG Xiaohong, LI Yi, XIANG Guangxin. Serotype and drug resistance of Salmonella from foodborne diseases in Longwan District. Preventive Medicine, 2025, 37(7): 697-700,704.
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