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预防医学  2020, Vol. 32 Issue (5): 478-482    DOI: 10.19485/j.cnki.issn2096-5087.2020.05.011
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常见儿童自身免疫性脑炎临床表现及防治进展
骆晓莹(综述), 江佩芳(审校)
浙江大学医学院附属儿童医院神经内科,浙江 杭州 310052
Research progress in clinical manifestations,prevention and treatment of common autoimmune encephalitis in children
LUO Xiaoying, JIANG Peifang
Department of Neurology,The Children's Hospital affiliated to Zhejiang University School of Medicine,Hangzhou, Zhejiang 310052,China
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摘要 自身免疫性脑炎是由自身免疫机制所介导的大脑炎症。近年来随着检测手段的精进和相关认知水平的提高,自身免疫性脑炎检出率增加,早期诊断和早期治疗是改善其预后的关键。儿童自身免疫性脑炎的临床表现不如成人典型,国内的自身免疫性脑炎专家共识并不完全适用于儿童,给临床诊断和防治带来极大挑战。本文对国内外儿童自身免疫性脑炎的流行情况、临床表现、诊断和防治等研究进行综述,为儿童自身免疫性脑炎诊断和防治提供参考。
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骆晓莹
江佩芳
关键词 自身免疫性脑炎抗N-甲基-D-天冬氨酸受体脑炎儿童抗体识别免疫治疗    
Abstract:Autoimmune encephalitis is a kind of brain inflammation mediated by immune mechanism. Recent years have witnessed its higher incidence with the improvement of detection technologies and knowledge. Early diagnosis and treatment are the key to improve the prognosis of autoimmune encephalitis. However,the clinical manifestations of autoimmune encephalitis in children is not as typical as those in adults,and our expert consensus on autoimmune encephalitis is not fully applicable to children,which brings great challenge to clinical diagnosis and prevention. This article reviews the research into the prevalence,clinical manifestations,diagnosis,prevention and treatment of autoimmune encephalitis in children at home and aboard,so as to provide reference for its diagnosis and prevention.
Key wordsautoimmune encephalitis    anti-N-methyl-D-aspartate receptor encephalitis    children    antibody detection    immunotherapy
收稿日期: 2019-11-15      修回日期: 2020-01-02      出版日期: 2020-05-10
中图分类号:  R512.3  
通信作者: 江佩芳,E-mail:jiangpeifang@zju.edu.cn   
作者简介: 骆晓莹,硕士,主要从事儿童神经系统疾病研究工作
引用本文:   
骆晓莹, 江佩芳. 常见儿童自身免疫性脑炎临床表现及防治进展[J]. 预防医学, 2020, 32(5): 478-482.
LUO Xiaoying, JIANG Peifang. Research progress in clinical manifestations,prevention and treatment of common autoimmune encephalitis in children. Preventive Medicine, 2020, 32(5): 478-482.
链接本文:  
http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2020.05.011      或      http://www.zjyfyxzz.com/CN/Y2020/V32/I5/478
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