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| Serotype and drug resistance of 815 Salmonella isolates in Hunan Province |
| LIU Fang, WANG Lan, ZHAN Zhifei, ZHANG Linqing, YUAN Qing, CHEN Shuai
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| Department of Microbiology, Hunan Provincial Center for Disease Control and Prevention, Changsha, Hunan 410000, China |
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Abstract Objective To investigate the serotype and drug resistance of 815 Salmonella isolates from Hunan Province, so as to provide insights into management of Salmonella infections. Methods Salmonella isolates were collected from stool samples of foodborne diarrheal patients and food samples in Hunan Province from 2020 to 2021, and serotyped. Antimicrobial susceptibility test was performed using the broth microdilution method. Results A total of 10 groups and 39 serotypes were characterized in 815 Salmonella isolates. Among the 646 Salmonella isolates of human sources, 388 isolates were identified as serogroup B (60.06%), with S. typhimurium and its variants aspredominant serotypes (364 isolates, 56.35%), and among 169 foodborne isolates, 61 isolates were characterized as serogroup B (36.09%) with S. london as the predominant serotype (26 isolates, 15.38%). There were 597 antimicrobial resistant Salmonella isolates of human sources, with a drug resistance rate of 92.41%, and the percentage of ampicillin resistance was 81.58%. There were 140 foodborne antimicrobial resistant isolates, with a drug resistance rate of 82.84%, and the proportion of tetracycline resistance was 72.78%. However, Salmonella isolates from both humans and foods were sensitive to imipenem. In addition, there were 577 multidrug resistant Salmonella isolates, including 490 multidrug resistant isolates of human sources and 87 foodborne multidrug resistant isolates. Conclusions S. typhimurium and its variants and S. london were predominant serotypes of Salmonella isolates from 815 foodborne diarrheal patients and food samples in Hunan Province from 2020 to 2021, and a high rate of multidrug resistance was detected.
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Received: 20 September 2022
Revised: 22 November 2022
Published: 21 February 2023
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[1] 周建松,简洁,蒋家俊,等.食源性沙门氏菌血清分型及分子分型分析[J].四川生理科学杂志,2022,44(5):753-756.
[2] 邹颜秋硕,杨祖顺,田云屏,等.2014—2018年云南省食源性沙门氏菌耐药监测分析[J].食品安全质量检测学报,2019,10(22):7601-7605.
[3] 苏良,杨柳青,宋迎春,等.2015—2019年长沙市食源性疾病沙门菌血清分型和耐药情况分析[J].实用预防医学,2022,29(1):82-84.
[4] 中华人民共和国国家卫生和计划生育委员会.食品安全国家标准食品微生物学检验沙门氏菌检验:GB 4789.4—2016[S].北京:中国标准出版社,2016:3-15.
[5] Clinical and Laboratory Standards Institute.Performance standards for antimicrobial susceptibility testing;twenty-first informational supplement:M100-S21[S].2011.
[6] 彭淑萍,李波,廖国东,等.广东省茂名市儿童食源性沙门菌感染的血清型分型和耐药特征[J].中国热带医学,2020,20(7):661-665.
[7] 曾献莹,吕素玲,杜悦,等.2016年广西壮族自治区食源性沙门菌的耐药性与耐药谱研究[J].中国食品卫生杂志,2018,30(1):22-27.
[8] 王岚,贾华云,张红,等.湖南省食源性沙门菌血清型分布及耐药性研究[J].实用预防医学,2011,18(6):994-997.
[9] 胡玉琴,章乐怡,李毅,等.温州市沙门菌血清型,耐药性和PFGE指纹图谱研究[J].预防医学,2019,31(6):640-642.
[10] 穆玉姣,张白帆,李懿,等.2011—2013年河南省沙门菌污染分布状况及其耐药研究[J].中国人兽共患病学报,2018,34(8):748-752.
[11] 张伟,金雪.细菌抗生素耐药机制和控制策略[J].现代医药卫生,2021,37(Suppl.1):16-17.
[12] 杨翊,贾华云,任国峰,等.2013—2017年湖南省沙门菌耐药状况及其分布[J].中国抗生素杂志,2020,45(6):621-626.
[13] 程古月,李俊,谷宇锋,等.世界卫生组织,欧盟和中国抗生素耐药性监测现状[J].中国抗生素杂志,2018,43(6):665-674.
[14] 陈建辉,欧剑鸣,陈伟伟,等.1984—2016年福建省人源与食品源沙门菌血清分型和耐药特征研究[J].疾病监测,2019,34(4):316-321.
[15] The National Antimicrobial Resistance Monitoring System.2015 integrated report[R/OL].Food and Drug Administration,2015[2022-11-22].https://www.cdc.gov/narms.
[16] European Food Safety Authority,European Centre for Disease Prevention and Control.The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans,animals and food in 2016[J/OL].EFSA J,2016(2)[2022-11-22].http://doi.org/10.2903/j.efsa.2018.5182.
[17] 刘跃华,韩萌,冉素平,等.欧洲应对抗生素耐药问题的治理框架及行动方案[J].中国医院药学杂志,2019,39(3):219-223. |
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