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Factors affecting osteoporosis among physical examination populations aged over 35 years in urban areas of Hangzhou City |
CHEN Yan, CHEN Jiali, ZHANG Zhishuang, GUO Shaoqiang
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Wenhui Street Community Health Service Center of Gongshu District, Hangzhou, Zhejiang 310014, China |
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Abstract Objective To investigate the development of osteoporosis (OS) and its influencing factors among physical examination populations aged over 35 years in urban areas of Hangzhou City, so as to provide insights into OP prevention. Methods Subjects aged over 35 years that underwent physical examinations in Wenhui Street Community Health Service Center of Gongshu District, Hanghzhou City during the period between April and July, 2022 were enrolled. Subjects' demographic characteristics and physical examination data were collected, and the bone mineral density and serum vitamin D levels were measured. The factors affecting the development of OP were identified using a logistic regression model. Results A total of 1 561 subjects were recruited, including 616 males (39.46%) with a median (interquartile range) age of 62 (18) years, and 945 females (60.54%) with a median (interquartile range) age of 62 (19) years. The prevalence of OP was 43.69% among the study subjects. Multivariable logistic regression analysis identified women (OR=1.367, 95%CI: 1.105-2.979) and increased age (OR=1.057, 95%CI: 1.044-1.069) as risk factors for OP and elevated serum 25-hydroxy-vitamin D levels as a protective factor for OP (OR=0.969, 95%CI: 0.954-0.985). Conclusions The prevalence of OP was 43.69% among physical examination populations aged over 35 years in urban areas of Hangzhou City, and gender, age and serum 25-hydroxy-vitamin D were factors affecting the development of OP.
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Received: 01 November 2022
Revised: 15 January 2023
Published: 21 February 2023
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[1] 中华医学会骨质疏松和骨矿盐疾病分会.中国骨质疏松症流行病学调查及“健康骨骼”专项行动结果发布[J].中华骨质疏松和骨矿盐疾病杂志,2019,12(4):317-318. [2] 陈婷,唐文革,丁贤彬,等.重庆市40岁及以上城市居民骨质疏松现状调查[J].中国慢性病预防与控制,2019,26(5):338-342. [3] 孙鑫鑫,杨斌,喻荣彬.南京市鼓楼区40岁及以上社区居民骨质疏松流行现状及与常见慢性病的关系[J].职业与健康,2020,31(23):3266-3268. [4] 谢兴文,林德民,李鼎鹏,等.维生素D相关信号通路干预对骨质疏松的影响[J].中国骨质疏松杂志,2021,27(9):1384-1387,1399. [5] DE MARTINIS M,ALLEGRA A,SIRUFO M M,et al.Vitamin D deficiency,osteoporosis and effect on autoimmune diseases and hematopoiesis:a review[J/OL].Int J Mol Sci,2021,22(16)[2023-01-15].https://doi.org/10.3390/ijms22168855. [6] 周柳娇,李吉,雷钧.中老年人群骨质疏松症影响因素分析[J].预防医学,2021,33(2):188-191. [7] 杨燕,杨琛,奚冬梅,等.陆家嘴社区老年人骨质疏松状况及影响因素分析[J].预防医学,2017,29(11):1104-1108. [8] 中华医学会骨质疏松和骨矿盐疾病分会.原发性骨质疏松症诊疗指南(2017)[J].中华骨质疏松和骨矿盐疾病杂志,2017,10(5):413-443. [9] 周影,潘卫民,肖欢,等.海口地区各年龄段人群骨密度变化及中老年骨质疏松患病率调查[J].中国骨质疏松杂志,2020,26(7):1054-1058. [10] 赵兰芳,王俊,王雪君.城市社区居民骨质疏松症影响因素分析[J].预防医学,2016,28(10):984-986. [11] 高玉婕,陈晓云,沙艳梅,等.大理白族自治州女性绝经后骨质疏松的影响因素分析[J].预防医学,2022,34(4):419-423. [12] 张礼超,薛青,周奕.不同类型维生素D3对原发性骨质疏松患者的影响[J].新疆医学,2019,49(7):690-693. [13] 裴育,董进,李梅.维生素D与骨质疏松[J].中华骨质疏松和骨矿盐疾病杂志,2018,11(1):44-50. [14] 何雪冬,王芳,廖顺琪,等.中国成人血清25羟维生素D水平与骨密度相关性的Meta分析[J].中国骨质疏松杂志,2021,27(6):808-812. [15] 郁静嘉,赵点点,王筱婧,等.血清25-羟维生素D和甲状旁腺激素水平与2型糖尿病患者骨密度的关系[J].中华内分泌代谢杂志,2015,31(4):306-310. [16] 何祺,黄定贵,范锲,等.维生素D、骨密度与颈椎不稳的相关性研究[J].微创医学,2022,17(4):481-483,525. |
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