|
|
|
| Pevalence of colorectal cancer in Yongjia County |
| ZHENG Pei, LU Liwei, ZHU Fugan, DAI Shujie
|
| Department of Chronic Diseases, Yongjia Center for Disease Control and Prevention, Yongjia, Zhejiang 325100, China |
|
|
|
|
Abstract Objective To investigate the prevalence of colorectal cancer in Yongjia County, Zhejiang Province from 2020 to 2021, so as to provide insights into colorectal cancer control. Methods Residents registered in Yongjia County at ages of 50 to 74 years were sampled, and positive populations were screened using Zhejiang Provincial Questionnaires for Assessment of Risk of Colorectal Cancer Screening among High-risk Populations and fecal occult blood test, and those positive for questionnaires or fecal occult blood test served as a positive screening. Residents with a positive screening underwent colonoscopy, and the detection of high-risk lesions (colorectal cancer and pericancer lesions) was analyzed among those positive for questionnaires, fecal occult blood test and screening. Results Totally 102 504 residents were tested, and 46 138 (45.01%) residents completed questionnaire surveys and fecal occult blood tests. The rate of positive screening was 21.10%, and the rate of positive questionnaire surveys was 7.13%, while the positive rate of fecal occult blood test was 15.16%. The rate of positive screening was significantly higher in men than in women (27.06% vs. 17.14%; (χ2=654.747, P<0.001), and there was an age-specific proportion of positive screening (χ2=418.264, P<0.001), with high prevalence seen in residents at ages of 65 to 69 years (26.43%) and 70 to 74 years (24.98%). Colonoscopy was performed among 2 966 residents, with a compliance rate of 30.47%, and colonoscopy detected 348 residents with high-risk lesions, including 317 cases with pericancer lesions and 31 cases with colorectal cancer, with 11.73% detection of high-risk lesions and 1.05% detection of colorectal cancer. The prevalence of high-risk lesions was significantly higher in men with positive screening than in women with positive screening (15.77% vs. 7.59%; χ2=47.915, P<0.001), and there was a significant difference in the detection of high-risk lesions among residents with positive screening at different age groups (χ2=25.909, P<0.001), with a high detection in residents at ages of 65 to 69 years (14.32%) and 70 to 74 years (15.49%). Conclusions The prevalence of high-risk lesions of colorectal cancer is 11.73% among residents living in Yongjia County at ages of 50 to 74 years, and men and the elderly at ages of 65 years and older are high-risk populations for colorectal cancer. Improving the awareness of colorectal cancer prevention knowledge and the compliance of colorectal cancer screening is recommended.
|
|
Received: 11 March 2022
Revised: 08 April 2022
Published: 19 July 2022
|
|
|
|
|
|
[1] 吴春晓,顾凯,龚杨明,等.2015年中国结直肠癌发病和死亡情况分析[J].中国癌症杂志,2020,30(4):241-245.
WU C X,GU K,GONG Y M,et al.Analysis of incidence and mortality of colorectal cancer in China,2015[J].China Oncol,2020,30(4):241-245.
[2] 刘宗超,李哲轩,张阳,等.2020全球癌症统计报告解读[J].肿瘤综合治疗电子杂志,2021,7(2):1-13.
LIU Z C,LI Z X,ZHANG Y,et al.Interpretation on the report of global cancer statistics 2020[J].J Multidiscipl Cancer Manag(Electron Version),2021,7(2):1-13.
[3] 朱陈,龚巍巍,钟节鸣,等.浙江省重点人群结直肠癌筛查项目设计和实施方案[J].中国肿瘤,2020,29(12):899-903.
ZHU C,GONG W W,ZHONG J M,et al.Zhejiang colorectal cancer screening program:overview and study design[J].China Cancer,2020,29(12):899-903.
[4] 国家癌症中心中国结直肠癌筛查与早诊早治指南制定专家组.中国结直肠癌筛查与早诊早治指南(2020,北京)[J].中华肿瘤杂志,2021,43(1):16-38.
National Cancer Center,Expert Group of the Development of China Guideline for the Screening,Early Detection and Early Treatment of Colorectal Cancer.China guideline for screening,early detection and early treatment of colorectal cancer(2020,Beijing)[J].Cnina J Oncol,2021,43(1):16-38.
[5] 柏愚,杨帆,马丹,等.中国早期结直肠癌筛查及内镜诊治指南(2014年,北京)[J].胃肠病学,2015,20(6):345-365.
BAI Y,YANG F,MA D,et al.Guidelines for early screening and endoscopic diagnosis and treatment of colorectal cancer in China(Beijing,2014)[J].Chin J Gastroenterol,2015,20(6):345-365.
[6] 马铭骏,李延青.探索中国结直肠癌筛查新模式[J].中国医刊,2021,56(12):1281-1284.
MA M J,LI Y Q.Explore new models of colorectal cancer screening in China[J].Chin J Med,2021,56(12):1281-1284.
[7] 王露尧,张鹭鹭.中国结直肠癌发病和死亡情况及防控策略[J].解放军医院管理杂志,2021,28(12):1195-1197.
WANG L Y,ZHANG L L.Incidence and mortality of colorectal cancer and prevention-control strategies in China[J].Hosp Adm J Chin PLA,2021,28(12):1195-1197.
[8] 宋洁,王静,张晓岚.《2021年美国胃肠病学会结直肠癌筛查指南》解读[J].临床荟萃,2021,36(9):828-831.
SONG J,WANG J,ZHANG X L.The guidelines for colorectal cancer screening by the American College of Gastroenterology in 2021-an interpretation[J].Clin Focus,2021,36(9):828-831.
[9] 王颖,潘峰,陈泽琨,等.北京市大兴区农村地区结直肠癌筛查结果及不同筛检工具比较[J].中国公共卫生,2020,36(1):41-46.
WANG Y,PAN F,CHEN Z K,et al.Colorectal cancer screening with questionnaire survey and fecal occult blood test among rural adults in Daxing district of Beijing:a comparison analysis[J].Chin J Public Health,2020,36(1):41-46.
[10] 覃勇军. 结直肠癌的发病因素及高危人群的预防对策[J].吉林医学,2021,42(6):1350-1352.
QIN Y J.The risk factors of colorectal cancer and the prevention strategies of high risk population[J].Jilin Med J,2021,42(6):1350-1352.
[11] 顾芳慧,杨雷,张希,等.北京市结直肠癌高危人群内镜筛查依从性分析及对策探讨[J].中国预防医学杂志,2021,22(6):428-433. GU F H,YANG L,ZHANG X,et al.Analysis on the compliance with endoscopic screening for colorectal cancer among high-risk population in Beijing[J].Chin Prev Med,2021,22(6):428-433.
[12] 师金,梁迪,李道娟,等.中国城市癌症早诊早治项目筛查依从性及影响因素研究[J].中国肿瘤,2021,30(8):591-599.
SHI J,LIANG D,LI D J,et al.Research on the screening compliance and influencing factors of cancer screening program in urban China[J].China Cancer,2021,30(8):591-599.
[13] 郑亦青. 老年人大肠癌筛查的动态分析及依从性研究[D].上海:上海交通大学,2016.
ZHENG Y Q.Dynamic observation and analysis on colorectal cancer screening in the elderly[D].Shanghai:Shanghai Jiao Tong University,2016.
[14] 杨金华,沈飞琼,薛峰,等.2007—2016年浙江省嘉善县结直肠癌筛查方案应用评价[J].中国肿瘤,2020,29(12):919-924.
YANG J H,SHEN F Q,XUE F,et al.Evaluation of colorectal cancer screening program in Jiashan County of Zhejiang Province,2007-2016[J].China Cancer,2020,29(12):919-924.
[15] 陈奇峰,陈康康,李金,等.2011—2019年绍兴市结直肠癌发病趋势分析[J].预防医学,2021,33(11):1146-1148.
CHEN Q F,CHEN K K,LI J,et al.Incidence trend of colorectal cancer in Shaoxing from 2011 to 2019[J].Prev Med,2021,33(11):1146-1148. |
|
|
|
