Abstract：Hyperhomocysteinemia has been recognized as a risk factor for cardiovascular and cerebrovascular diseases,which is involved in the occurrence and development of the diseases. It has been found recently that the increase of homocysteine is closely related to recurrent pregnancy loss,gestational hypertension,gestational diabetes mellitus and the success rate of assisted reproductive technology. Homocysteine is concerned as a controllable factor for pregnancy-associated diseases. This article reviews the studies into the relationship between homocysteine and pregnancy-associated diseases,so as to provide evidence for future research on pathogenesis and prognosis of pregnancy-associated diseases.
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