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| The application of breast blood oxygen functional imaging combined with mammography examination in breast cancer screening |
| WANG Hong-yan,SONG Yong-mao,XIE Pei-pei,WU Hai-yan,WEI Jing
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| The Affiliated Hospital of Hangzhou Normal University ,Hangzhou,Zhejing,310015,China |
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Abstract Objective To evaluate the effect of breast blood oxygen functional imaging combined with mammography on breast cancer screening in women aged over 40 years. Methods A total of 10 076 cases of women in our hospital underwent breast blood oxygen functional imaging and mammography X-ray examination. The breast imaging report and data system (BI-RADS) III level of women performed on the biopsy pathology were used as the gold standard. The effect of different inspection methods were compared and analyzed. Results Among 10 076 cases, 235 cases were diagnosed as BI-RADS, which was diagnosed by blood oxygen functional imaging system and a molybdenum target X-ray diagnosis of III. Thirteen cases with early breast cancer were diagnosed by needle biopsy. And 222 cases were diagnosed benign lesions. The sensitivity of the blood oxygen functional imaging system was 69.23% (9/13) and 85.58% (190/222), respectively. The sensitivity of molybdenum target X-ray was 76.92% (10/13), and the specificity was 82.88% (184/222). The sensitivity of combined detection was 100.0% (13/13) and the specificity was 82.88% (184/222). The accuracy index of combined molybdenum target X-ray (0.829) was significantly higher than that of single detection (0.548 and 0.598) (U=2.117, 2.501, P<0.05). Conclusion Breast blood oxygen functional imaging instrument combined with molybdenum target examination could effectively improve the accuracy of diagnosis in breast cancer screening among women over 40 years.
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Published: 25 December 2017
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