|
|
|
| Self-reported chronic disease prevalence among HIV/AIDS patients aged 50 years and above receiving antiretroviral therapy in Wuxi City |
| LI Qian, YANG Bolin, CHEN Jibiao, YIN Hanlu, XU Zhuping, MENG Xiaojun
|
| The Affiliated Wuxi Center for Disease Control and Prevention of Nanjing Medical University, Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu 214023, China |
|
|
|
|
Abstract Objective To investigate the prevalence of hypertension, diabetes and hyperlipidemia among HIV/AIDS patients aged 50 years and above receiving antiretroviral therapy (ART) in Wuxi City, Jiangsu Province, so as to provide insights into the prevention and intervention of chronic diseases for these populations. Methods The HIV/AIDS patients aged 50 years and above receiving ART were recruited at designated HIV/AIDS medical institutions in Wuxi City using the convenient sampling method from March to June 2024. Demographic information, treatment status and self-reported prevalence of hypertension, diabetes and hyperlipidemia were collected through questionnaire surveys. Factors affecting the prevalence of chronic diseases were analyzed using a multivariable logistic regression model. Results A total of 830 HIV/AIDS patients receiving ART were surveyed, including 656 males (79.04%) and 375 patients aged 50 to <60 years (45.18%). Among them, 366 patients reported having at least one type of chronic disease, including hypertension, diabetes and hyperlipidemia, with a self-reported prevalence rate of 44.10%. Specifically, 280, 114 and 61 patients reported having hypertension, diabetes and hyperlipidemia, with the self-reported prevalence rates of 33.73%, 13.73% and 7.35%, respectively. Multivariable logistic regression analysis showed that male patients (OR=1.725, 95%CI: 1.187-2.507), those with monthly income less than 3 000 yuan (OR=1.521, 95%CI: 1.122-2.063), those with body mass index of 24 kg/m2 and above (OR=1.577, 95%CI: 1.168-2.130), those who initiated ART at ages of 50 years and above (50 to <60 years, OR=1.535, 95%CI: 1.052-2.238; ≥60 years, OR=3.322, 95%CI: 2.191-5.038), those with ART duration of 10 years and above (OR=2.069, 95%CI: 1.419-3.017), and those who received non-first-line regimens (OR=1.776, 95%CI: 1.304-2.418) had higher risks of developing at least one type of chronic disease, including hypertension, diabetes and hyperlipidemia. Conclusions The self-reported prevalence of at least one type of chronic disease, including hypertension, diabetes and hyperlipidemia among HIV/AIDS patients aged 50 years and above receiving ART in Wuxi City was 44.10%. Gender, monthly income, body mass index and ART status are the main influencing factors for the risk of chronic diseases.
|
|
Received: 03 December 2024
Revised: 20 February 2025
Published: 16 April 2025
|
|
|
|
|
|
[1] 蒋均,罗明宇,杨介者,等.2015—2019年浙江省新确证50岁及以上HIV/AIDS病例流行特征分析[J].预防医学,2020,32(8):762-766,773.
JIANG J,LUO M Y,YANG J Z,et al.Epidemiological characteristics of newly diagnosed HIV/AIDS cases aged 50 years or over in Zhejiang Province from 2015 to 2019[J].China Prev Med J,2020,32(8):762-766,773.(in Chinese)
[2] 张晗希,韩孟杰,周郁,等.我国50岁及以上人群HIV感染率的Meta分析[J].中华流行病学杂志,2020,41(1):96-102.
ZHANG H X,HAN M J,ZHOU Y,et al.HIV infection rate in people aged 50 years and older in China:a meta-analysis[J].Chin J Epidemiol,2020,41(1):96-102.(in Chinese)
[3] 杨锦,李晓晗,唐仁海,等.云南省德宏州接受抗病毒治疗的HIV感染者多病共患情况分析[J].上海预防医学,2024,36(9):846-853.
YANG J,LI X H,TANG R H,et al.Prevalence of multimorbidity among the HIV-infected individuals receiving anti-viral therapy in Dehong Prefecture,Yunnan Province[J].Shanghai J Prev Med,2024,36(9):846-853.(in Chinese)
[4] 叶荣,顾菁.HIV/AIDS患者常见慢性病患病情况[J].中国艾滋病性病,2023,29(12):1371-1375.
YE R,GU J.A review of the disease frequency to chronic noncommunicable diseases common among HIV/AIDS[J].Chin J AIDS STD,2023,29(12):1371-1375.(in Chinese)
[5] 严翔. 安徽省老年HIV/AIDS患者慢性病患病现况研究[D].合肥:安徽医科大学,2021.
YAN X.Cross-sectional study on prevalence of chronic noncommunicable diseases among people living with HIV/AIDS aged over fifty in Anhui Province[D].Hefei:Anhui Medical University,2021.(in Chinese)
[6] 徐小慧,何春燕,何纳,等.HIV感染者高血压患病率及其影响因素研究近况[J].上海预防医学,2021,33(12):1166-1175.
XU X H,HE C Y,HE N,et al.A systematic review of the prevalence and influence factors of hypertension among HIV-infected individuals[J].Shanghai J Prev Med,2021,33(12):1166-1175.(in Chinese)
[7] 李智慧,沙敏,杨磊,等.HIV/AIDS患者血脂异常、高血糖患病率及影响因素分析[J].中国性科学,2024,33(12):135-139.
LI Z H,SHA M,YANG L,et al.Analysis of the prevalence rate of dyslipidemia and hyperglycemia in human immunodeficiency virus/acquired immunodeficiency syndrome patients and its influencing factors[J].Chin J Hum Sexuality,2024,33(12):135-139.(in Chinese)
[8] 张洁,费方荣,胡如英,等.浙江省慢性病主要危险因素的归因疾病负担研究[J].预防医学,2022,34(6):541-546,554.
ZHANG J,FEI F R,HU R Y,et al.Burden of disease attributable to main risk factors of chronic diseases in Zhejiang Province[J].China Prev Med J,2022,34(6):541-546,554.(in Chinese)
[9] 马茹,贾清,马雨馨,等.基于结构方程模型的青海省西宁市HIV感染者和AIDS患者高血压患病影响因素分析[J].中国慢性病预防与控制,2024,32(4):254-259.
MA R,JIA Q,MA Y X,et al.Analysis on influencing factors of hypertension among HIV infected cases/AIDS cases in Xining city of Qinghai Province based on structural equation model[J].Chin J Prev Contr Chron Dis,2024,32(4):254-259.(in Chinese)
[10] 贾皇超,姜琦,金艳涛,等.中老年人类免疫缺陷病毒和获得性免疫缺陷综合征患者血脂异常的相关危险因素分析[J].中华老年心脑血管病杂志,2022,24(5):456-459.
JIA H C,JIANG Q,JIN Y T,et al.Risk factors for dyslipidemia in middle-aged and elderly HIV-infected and AIDS patients[J].Chin J Geriatr Heart Brain Ves Dis,2022,24(5):456-459.(in Chinese)
[11] 黄满秀,陈根秀,谢满.老年HIV/AIDS病人共病的研究进展[J].全科护理,2023,21(31):4367-4371.
HUANG M X,CHEN G X,XIE M.Research advances in comorbidities among elderly patients with HIV/AIDS[J].Chin Gen Pract Nurs,2023,21(31):4367-4371.(in Chinese)
[12] MAGGI P,DE SOCIO G V,MENZAGHI B,et al.Growing old with antiretroviral therapy or elderly people in antiretrov iral therapy:two different profiles of comorbidity?[J].BMC Infect Dis,2022,22(1):745-752.
[13] 翟优,赵英强,刘亚楠,等.河南某地区经性传播途径感染艾滋病患者高脂血症患病率及影响因素分析[J].中国皮肤性病学杂志,2021,35(8):897-903.
ZHAI Y,ZHAO Y Q,LIU Y N,et al.Prevalence and influencing factors of hyperlipidemia in sexually transmitted AIDS patients in a district of Henan Province[J].Chin J Dermatovenereol,2021,35(8):897-903.(in Chinese)
[14] LAGATHU C,BÉRÉZIAT V,GORWOOD J,et al.Metabolic complications affecting adipose tissue,lipid and glucose me tabolism associated with HIV antiretroviral treatment[J].Expert Opin Drug Saf,2019,18(9):829-840.
[15] 刘宇丹,张彩云,郭明媚,等.慢性病共病患者服药依从性影响因素的Meta分析[J].预防医学,2024,36(9):790-795,800.
LIU Y D,ZHANG C Y,GUO M M,et al.Influencing factors for medication compliance in patients with comorbidities of chronic diseases:a meta-analysis[J].China Prev Med J,2024,36(9):790-795,800.(in Chinese)
[16] 杨红红,余庆,李梅,等.抗反转录病毒治疗对HIV/AIDS患者代谢综合征影响的研究进展[J].中国艾滋病性病,2024,30(11):1206-1210.
YANG H H,YU Q,LI M,et al.Research progress on the impact of antiretroviral therapy on metabolic syndrome in people living with HIV[J].Chin J AIDS STD,2024,30(11):1206-1210.(in Chinese) |
|
|
|
