|
|
Factors affecting lumbar disc herniation among elderly patients with osteoporosis |
MEN Xin, LIU Mingming, WANG Hui
|
Department of Spine Surgery, Beijing Jishuitan Hospital Affiliated to Capital Medical University, Beijing 100035, China |
|
|
Abstract Objective To investigate the influencing factors of lumbar disc herniation (LDH) among elderly patients with osteoporosis (OP), so as to provide the basis for early prevention of LDH in OP patients. Methods The patients aged 60 years and above with OP who were treated in the clinic of Beijing Jishuitan Hospital from December 2022 to December 2023 were recruited as the study subjects. The data of demographic and clinical information were collected through the hospital medical record system. LDH was diagnosed according to the LDH Diagnosis and Treatment Guidelines. Factors affecting LDH among elderly patients with OP were identified using a multivariable logistic regression model. Results A total of 500 patients with OP were included, with 188 males (37.60%) and 312 females (62.40%). The mean age was (69.05±3.28) years, and the course of OP was (6.37±2.11) years. There were 196 patients living alone, accounting for 39.20%. LDH among elderly patients with OP were detected in 78 cases, accourcing for 15.60%. Multivariable logistic regression analysis showed that the patients who were at ages of 70 years and above (OR=1.465, 95%CI: 1.197-1.793), lived alone (OR=1.777, 95%CI: 1.093-2.889), had a history of fracture (OR=1.799, 95%CI: 1.070-3.023) and scored higher in quality of life (OR=1.405, 95%CI: 1.230-1.605) were at higher risks of LDH, while the patients who had a history of taking calcium supplements (OR=0.562, 95%CI: 0.345-0.915) were at lower risks of LDH. Conclusion Age, living situation, history of fracture, history of taking calcium supplements and quality of life were influencing factors for LDH among elderly patients with OP.
|
Received: 06 May 2024
Revised: 21 September 2024
Published: 14 November 2024
|
|
|
|
|
[1] 杨波,陈任,潘阳,等.蚌埠市蚌山区老年人群骨质疏松症流行病学调查及对跌倒风险和认知功能的影响[J].现代生物医学进展,2023,23(1):113-117. [2] 卢建峰,王志超,卢廷胜,等.老年腰椎间盘突出症特点与开放减压椎间盘切除[J].中国矫形外科杂志,2022,30(6):563-565. [3] EKRAM S,KHALID S,BASHIR I,et al.Human umbilical cord-derived mesenchymal stem cells and their chondroprogenitor derivatives reduced pain and inflammation signaling and promote regeneration in a rat intervertebral disc degeneration model[J].Mol Cell Biochem,2021,476(8):3191-3205. [4] 方明,陆建猛,王兴武,等.老年女性骨质疏松椎体压缩骨折与下腰椎多裂肌椎间盘退变及腰椎-骨盆参数的关系[J].中华老年医学杂志,2021,40(5):628-631. [5] 魏戌,刘宁,章轶立,等.骨质疏松症的共病研究与早期筛查[J].中国全科医学,2022,25(35):4369-4374. [6] LI H Q,WALLIN M,BARREGARD L,et al.Smoking-induced risk of osteoporosis is partly mediated by cadmium from tobacco smoke:the MrOS Sweden Study[J].J Bone Miner Res,2020,35(8):1424-1429. [7] 熊绪,刘家明,陈伟文,等.江西地区骨质疏松性椎体骨折的诊疗现状调查[J].中国骨质疏松杂志,2023,29(8):1135-1140. [8] 中华医学会骨质疏松和骨矿盐疾病分会.原发性骨质疏松症诊疗指南(2017)[J].中国实用内科杂志,2018,38(2):127-150. [9] 李明晖,罗南.欧洲五维健康量表(EQ-5D)中文版应用介绍[J].中国药物经济学,2009(1):49-57. [10] 中华医学会骨科学分会脊柱外科学组,中华医学会骨科学分会骨科康复学组.腰椎间盘突出症诊疗指南[J].中华骨科杂志,2020,40(8):477-487. [11] 韩涛,孙凯,孙传睿,等.骨质疏松症与腰椎间盘突出症共病调查及影响因素分析[J].中国全科医学,2022,25(35):4375-4380. [12] 高玉婕,陈晓云,沙艳梅,等.大理白族自治州女性绝经后骨质疏松的影响因素分析[J].预防医学,2022,34(4):419-423,428. [13] 朱换平,石敏,张维平,等.杜仲腰痛丸调控p53对老年骨质疏松症患者骨密度,骨代谢及骨形成影响的作用机制[J].中国骨质疏松杂志,2021,27(2):257-262. [14] 赵永凯. 年龄对经皮椎间孔镜治疗腰椎间盘突出症疗效的影响[J].临床骨科杂志,2023,26(2):177-181. [15] 林凤绣,李志敏,赖智君.肌内效贴结合核心稳定性训练对老年腰椎间盘突出症患者疼痛和功能恢复的影响[J].中国老年学杂志,2023,43(5):1097-1100. [16] 沈晓君,蔡文玮,荀雪琴,等.上海市老西门街道社区60岁以上老年人跌倒的现状及危险因素分析[J].中国临床保健杂志,2020,23(6):770-773. [17] 崔庆同,曹艺萌,王平.中医药联合疗法治疗腰4椎体压缩性骨折合并腰椎间盘突出症验案1例[J].天津中医药,2020,37(8):925-928. [18] 刘树华,王若琳,陈桐莹,等.骨质疏松慢性疼痛的分类及其与溶酶体-VNUT-ATP的关系[J].中国骨质疏松杂志,2022,28(5):713-717. [19] 张露,江流,曹慧,等.60岁及以上人群骨质疏松症的影响因素分析[J].预防医学,2024,36(3):235-238. |
[1] |
LIU Yudan, ZHANG Caiyun, GUO Mingmei, ZHENG Yujuan, JIA Ming, YANG Jiale, HOU Jianing, ZHAO Hua. Influencing factors for medication compliance in patients with comorbidities of chronic diseases: a meta-analysis[J]. Preventive Medicine, 2024, 36(9): 790-795,800. |
|
|
|
|