|
|
HIV infection and influencing factors in spouses of HIV/AIDS |
CHEN Hai-yan,MA Gong-yan,CHEN Dong
|
Department of STD and AIDS Prevention and Control,Lu'an Center for Disease Control and Prevention,Lu'an,Anhui 237000,China |
|
|
Abstract Objective To learn the HIV infection status and related factors among spouses of HIV/AIDS. Methods We recruited HIV/AIDS cases diagnosed between January 2000 and August 2016 in Lu'an and their spouses to collect the demographic information and sexual behavior characteristics. For HIV sero-accordant spouses,we analyzed influencing factors for HIV infection by logistic regression model; while for HIV sero-discordant spouses,we followed up until December 31,2016 and detected their HIV antibody periodically. Results The HIV infection rate of spouses was 20.35%(47/231). Forty-five of the spouses had been infected with HIV before our investigation,with a infection rate of 19.48%(45/231). Two of the spouses developed positive HIV antibody during the follow-up with a positive conversion rate of 0.39/100 person-years. Multivariate logistic regression analysis indicated that high frequency of sexual contacts before confirmed as HIV positive(OR≥1/week= 6.268,95%CI:2.313-16.985;OR1/half a month=3.760,95%CI:1.268-11.150)and diagnosis during 2011-2014(OR=3.079,95%CI:1.209-7.841)were the risk factors for HIV transmission between couples; under the age of 25(OR=0.042,95%CI:0.004-0.467)when confirmed as HIV positive and early viral load<300 copies/mL(OR=0.115,95%CI:0.045-0.295)were protective factors. Conclusion HIV transmission of spouses is associated with frequency of sexual contacts,time of diagnosis,age when confirmed as HIV positive and early viral load.
|
Published: 06 July 2018
|
|
|
|
|
[1] 郝阳,崔岩,孙新华,等. “四免一关怀”政策实施十年来中国艾滋病疫情变化及特征分析[J]. 中华疾病控制杂志,2014, 18(5):369-374. [2] 中国疾病预防控制中心. 2016年12月全国艾滋病性病疫情[J]. 中国艾滋病性病,2017,23(2):93. [3] 惠珊,许艳,王璐,等. 部分省市艾滋病异性性传播方式构成及特征分析[J]. 疾病监测,2011,26(6):42-46. [4] 王丽艳,丁正伟,秦倩倩,等. 2008—2014年中国艾滋病经异性性途径传播的流行特征分析[J]. 中华流行病学杂志,2015, 36(12):1332-1335. [5] UNAIDS. AIDS epidemic update[EB/OL].(2007-11-15)[2017-10-09].http://data.unaids.org/pub/EPISlides/2007/2007- epiu-pdate-en.pdf. [6] KUMARASAMY N,VENKATESH K K,SRIKRISHNAN A K,et al.Risk factors for HIV transmission among heterosexual discordant couples in South India[J].HIV Med,2010,11(3):178-186. [7] 陈琳,潘晓红,杨介者,等. 浙江省2009—2013年单阳家庭配偶HIV血清学阳转率分析[J]. 中华流行病学杂志,2015, 36(8):857-861. [8] 徐智贤,王志苏,李春梅. 232例HIV/AIDS配偶/固定性伴HIV抗体检测结果分析[J]. 中国卫生检验杂志,2013,23(5):1245-1247. [9] 马功燕,陈海燕,陈进.艾滋病夫妻传播队列研究[J]. 公共卫生与预防医学,2013,24(5):54-56. [10]李洁,马彦民,孙定勇,等. 河南省2006—2010年艾滋病单方阳性配偶阳转状况分析[J]. 中华流行病学杂志,2012,33(1):71-74. [11]朱琳,王岚,刘慧鑫,等. 2012年河南省驻马店市HIV单阳家庭阴性配偶阳转情况及其影响因素分析[J]. 中国艾滋病性病,2013,19(11):798-801. [12]WALL K M,KILEMBE W,VWALIKA B,et al. Sustained effect of couples' HIV counselling and testing on risk reduction among Zambian HIV serodiscordant couples[J]. Sex Transm Infect,2017, 93(4):259-266. [13]QUINN T C,WAWER M J,SEWANKAMBO N,et al. Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group[J]. N Engl J Med,2000,342(13):921-929. [14]卢巧玲,杨作凯,方益荣,等. 绍兴市15~24岁青少年HIV/AIDS特征分析[J]. 预防医学,2017,29(10):987-990. [15]杨兵,沈云峰,俞素芬,等. 湖州市吴兴区老年人群艾滋病流行特征分析[J]. 预防医学,2017,29(10):1041-1043. [16]明帅,王岚,王璐,等. 驻马店市抗病毒治疗“单阳家庭”夫妻间性传播HIV影响因素分析[J]. 中国艾滋病性病,2012,18(5):276-280. |
|
|
|