|
|
|
| Influencing factors for anxiety symptoms among human papilloma virus-infected women |
| BAI Maochao1, LI Fen2, Dilinuer Tuerxun2, Remila Rezhake2, WANG Yan2
|
1. School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830011, China;
2. Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830011, China |
|
|
|
|
Abstract Objective To investigate the influencing factors for anxiety symptoms among human papilloma virus (HPV)-infected women, so as to provide the evidence to improve the mental health of HPV-infected women. Methods HPV-infected women visiting the gynecology department of a tertiary hospital in Urumqi from September to December 2024 were selected using a convenience sampling method. Basic information of HPV-infected women and information related to HPV infection were collected through a self-designed questionnaire. Anxiety symptoms was assessed by using the Generalized Anxiety Disorder-7 (GAD-7), with a GAD-7 score of ≥5 determined to be the presence of anxiety symptoms. Factors affecting anxiety symptoms in HPV-infected women were analyzed using a multivariable logistic regression model. Results A total of 436 HPV-infected women were investigated. Among them, 361 (82.80%) were aged 30-<60 years old, 286 (65.60%) had a high school/technical secondary school or above, 361 (82.80%) had a spouse, 389 (89.22%) had given birth, and 234 (53.67%) had a family monthly income of less than 5 000 yuan. There were 90 HPV-infected women with multiple HPV infections, accounting for 20.64%. The sexual life of 155 people was affected, accounting for 35.55%. A total of 165 HPV-infected women with anxiety symptoms were detected, with a detection rate of 37.84%. Multivariable logistic regression analysis showed that multiple HPV infections (OR=1.776, 95%CI: 1.068-2.954), HPV infection time <3 months (OR=1.858, 95%CI: 1.132-3.050), lack of HPV-related knowledge (OR=1.742, 95%CI: 1.045-2.905), sexual life was affected (OR=3.480, 95%CI: 2.146-5.642), and monthly family income was less than 5 000 yuan (OR=1.815, 95%CI: 1.119-2.946) had a higher risk of anxiety symptoms. Conclusions The detection rate of anxiety symptoms in HPV-infected women is high. The type of HPV infection, the duration of HPV infection, the understanding of HPV-related knowledge, the impact on sexual life, and the monthly family income are influencing factors of anxiety symptoms among HPV-infected women.
|
|
Received: 23 January 2025
Revised: 15 May 2025
Published: 24 June 2025
|
|
|
|
|
|
[1] FASHEDEMI O,OZOEMENA O C,PETENI S,et al.Advances in human papillomavirus detection for cervical cancer screening and diagnosis:challenges of conventional methods and opportunities for emergent tools[J].Anal Methods,2025,17(7):1428-1450.
[2] FONTHAM E T H,WOLF A M D,CHURCH T R,et al.Cervical cancer screening for individuals at average risk:2020 guideline update from the American cancer society[J].CA Cancer J Clin,2020,70(5):321-346.
[3] 史学艳,王志莲.HPV感染对女性心理健康的影响[J].中国计划生育和妇产科,2022,14(12):65-68.
SHI X Y,WANG Z L.Impact of HPV infection on women's mental health[J].Chin J Fam Plann Gynecotokol,2022,14(12):65-68.(in Chinese)
[4] DODD R H,MAC O,BROTHERTON J M L,et al.Levels of anxiety and distress following receipt of positive screening tests in Australia's HPV-based cervical screening programme:a cross-sectional survey[J].Sex Transm Infect,2020,96(3):166-172.
[5] 王福媛,王朝霞,赵乐,等.生物钟节律相关因素对女性HPV转阴影响的前瞻性队列研究[J].中国癌症防治杂志,2022,14(5):552-557.
WANG F Y,WANG Z X,ZHAO L,et al.A prospective cohort study on the effect of circadian clock rhythm related factors on female HPV negative conversion[J].Chin J of Oncol Prev and Treat,2022,14(5):552-557.(in Chinese)
[6] 杨瑞,马晓艳,陆柔君,等.HPV感染女性不良社会心理状态及影响因素研究综述[J].医学与社会,2024,37(12):97-104.
YANG R,MA X Y,LU R J,et al.Reasearch review of adverse sociopsychological status and influencing factors in women infected with HPV[J].Med Soc,2024,37(12):97-104.(in Chinese)
[7] SPITZER R L,KROENKE K,WILLIAMS J B,et al.A brief measure for assessing generalized anxiety disorder:the GAD-7[J].Arch Intern Med,2006,166(10):1092-1097.
[8] 刘婷婷,孔为民,胡晓頔,等.HPV感染患者焦虑现状及相关影响因素分析[J].国际妇产科学杂志,2020,47(2):236-240.
LIU T T,KONG W M,HU X D,et al.Anxiety status and related influencing factors in patients with HPV infection[J].J Int Obstet Gynecol,2020,47(2):236-240.(in Chinese)
[9] 马燕娟,徐沛琳,古力努尔·艾比不拉,等.乌鲁木齐市焦虑障碍现况调查[J].中国心理卫生杂志,2022,36(12):1005-1009.
MA Y J,XU P L,AIBIBULA G L N E,et al.A cross-sectional study of anxiety disorder in Urumqi[J].Chin Ment Health J,2022,36(12):1005-1009.(in Chinese)
[10] ARTHUR A W,El-ZEIN M,BURCHELL A N,et al.Detection and clearance of type-specific and phylogenetically related genital human papillomavirus infections in young women in new heterosexual relationships[J].J Infect Dis,2024,229(3):691-706.
[11] MBOUMBA BOUASSA R S,PÉRÉ H,JENABIAN M A,et al.Natural and vaccine-induced B cell-derived systemic and mucosal humoral immunity to human papillomavirus[J].Expert Rev Anti Infect Ther,2020,18(6):579-607.
[12] 徐冬冬,韩月欣,纪红玉.高危型人乳头瘤病毒感染者心理健康状况调查及影响因素分析[J].中国计划生育学杂志,2022,30(7):1491-1495.
XU D D,HAN Y X,JI H Y.Investigation of psychological health status of patients with high-risk human papillomavirus infection and its influencing factors analysis[J].Stud J Fam Plann,2022,30(7):1491-1495.(in Chinese)
[13] 罗潇,乔孔明.互联网+模式下宫颈癌合并HPV感染现状及心理影响因素调查分析[J].贵州医药,2024,48(4):574-576.
LUO X,QIAO K M.Investigation and analysis of the current situation of cervical cancer combined with HPV infection and psychological influencing factors under the Internet+ model[J].Guizhou Medical J,2024,48(4):574-576.(in Chinese)
[14] KIM M,PARK N J,JEONG J Y,et al.Multiple human papilloma virus(HPV)infections are associated with HSIL and persistent HPV infection status in korean patients[J].Viruses,2021,13(7):1342-1352.
[15] NICK N,TORABIZADEH C,GHAHARTARS M,et al.Adaptation of patients diagnosed with human papillomavirus:a grounded theory study[J/OL].Reprod Health,2021,18(1)[2025-05-15].https://doi.org/10.1186/s12978-021-01264-y.
[16] 刘芳. 宫颈HPV阳性患者焦虑现状及其与社会支持的相关性分析[D].大连:大连医科大学,2021.
LIU F.Correlation analysis of anxiety status and social support in cervical HPV-positive patients[D].Dalian:Dalian Medical University,2021.(in Chinese)
[17] 刘艳梅,施桑桑,吴聪泉,等.HPV感染者的心理现状及相关影响因素研究[J].中国妇幼健康研究,2023,34(6):75-81.
LIU Y M,SHI S S,WU C Q,et al.Study on psychological status and related influencing factors of HPV-infected patients[J].Chin J Woman Child Health Res,2023,34(6):75-81.(in Chinese) |
|
|
|
