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| Assessment and intervention of frailty in the elderly：a review |
| GUO Liangmei, SONG Wenjuan, ZENG Qiang
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| The Second Medical Center&National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100039, China |
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Abstract Frailty is a clinical state characterized by increased vulnerability due to the decline of multiple organ functions. It is clinically manifested as slow movement, reduced activity, low energy level and involuntary weight loss. Frailty heightens the risk of disability, long-term hospitalization and mortality in the elderly when they face stressful events. Early assessment of frailty and personalized interventions can prevent and delay its progression, thereby reducing the occurrence of adverse events. This article reviews the literature on frailty published both domestically and internationally from January 2015 to January 2024. It provides an overview of the tools for assessing frailty in the elderly, such as the Clinical Frailty Scale, Frailty Index, Fried Frailty Phenotype, FRAIL Scale, and biological markers, and the management of frailty, including exercise, nutritional interventions, oral health management, and medication management, so as to provide the evidence for early assessment and intervention of frailty.
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Received: 12 October 2024
Revised: 27 January 2025
Published: 17 March 2025
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