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| Regulatory function of long noncoding RNA MAGI2-AS3 in tumor development: a review |
| GU Simeng1, LI Yahui2, WANG Xiaofeng1, MO Zhe1
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1. Department of Environmental Health, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051, China;
2. Hangzhou Medical College, Hangzhou, Zhejiang 310012, China;
3. Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051, China |
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Abstract Long noncoding RNA (lncRNA) is closely related to the pathogenesis of cancer,representing a burgeoning field in tumor research in recent years. MAGI2-AS3, a tumor-associated lncRNA, exerts pivotal roles in epigenetics, transcription and post-transcriptional regulation. Studies have suggested that MAGI2-AS3 may be involved in multiple stages of tumor development, and has potential applications for tumor diagnosis, therapy and prognosis. This review summarizes the expression, regulatory mechanism and clinical application value of MAGI2-AS3 in common malignant tumrs, providing the reference for tumor prevention and treatment.
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Received: 22 March 2024
Revised: 25 May 2024
Published: 19 July 2024
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