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| Research progress on ecotoxicological effects of antidepressants |
| NIU Huixia1, WANG Xiaofeng2, LOU Xiaoming2
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1. School of Medicine, Ningbo University, Ningbo, Zhejiang 315000, China;
2. Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051, China |
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Abstract With the increasing rise in antidepressant consumption, more and more antidepressants and their metabolic products enter into water and soil environments. This will cause toxicity to animals living in these environments, and antidepressants may be transferred to humans via food chain, leading to human health risks. Based on national and international publications pertaining to environmental pollution and toxic effects of antidepressants during the period between 2005 and 2021, this review summarizes the biological accumulation, acute toxicity, reproductive and developmental toxicity, metabolic effects and biological behavior changes of antidepressants, so as to provide insights into the elucidation of the impact of antidepressants on human health risks.
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Received: 26 April 2022
Revised: 16 June 2022
Published: 08 September 2022
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