Abstract：Objective To study the effect of comprehensive prehospital management for patients with emergency trauma treatment.Methods Fifty emergency patients who were admitted to the emergency department were investigated respectively before and after the implementation of the comprehensive prehospital management of the people's hospital of Gaozhou City，with the service satisfaction questionnaire，the Anxiety Self-assessment Scale（SAS）and the Depression Self-rating Scale（SDS）. The time of admission，first aid time，emergency treatment effect，satisfaction and mental status change of the two groups were compared.Results There was no statistically significant difference in age，gender，cause of injury and distribution of injury in the two groups（P>0.05）. The admission time and first aid time of the patients in the observation group respectively were（15.6±4.2）and（33.5±8.4）minutes，which were shorter than the control group of（24.3±5.0）and（60.5±10.2）minutes（P<0.05）. The emergency effect and satisfaction of the observation group were superior to the control group（P<0.05）. The difference between SAS and SDS scores in the observation group was 21.3 ±3.4 and 20.4±3.1，both of them were higher than the control group（12.1±2.7 and 12.8±2.5）（P<0.05）.Conclusion The comprehensive pre-hospital management can shorten the time of admission and first aid，and effectively improve the clinical treatment effect and satisfaction of emergency trauma patients.