Abstract：Objective To explore the prevalence and trend of premature delivery in Shaoxing Maternal and Child Health Care Hospital from 2007 to 2018, so as to provide evidence for prevention of premature birth and promotion of perinatal health care. Methods The data of live births in Shaoxing Maternal and Child Health Care Hospital from 2007 to 2018 were collected,and premature birth rate,proportion of premature infants in different gestational weeks,as well as the trend of gender ratio,asphyxia and birth weight with gestational weeks were analyzed. Results From 2007 to 2018,there were 10 506 premature infants born in Shaoxing Maternal and Child Health Care Hospital. The preterm birth rate increased year by year （P<0.05）,and the annual average was 9.09%. The rate of multiple premature birth was 57.80%,which was higher than that of single premature birth （7.26%,P<0.05）. There were 110 cases of extremely preterm birth （1.05%）,2 997 cases of early preterm birth （28.53%）,and 7 399 cases of mild preterm birth （70.43%）. The proportions of extremely and early preterm birth increased year by year （P<0.05）. The asphyxia rate of premature infants was 9.70% （1 019 cases）,which decreased with the increase of gestational weeks （P<0.05）. The birth weight of premature infants decreased with the increase of gestational weeks （P<0.05）. The ratio of male to female in preterm infants was 1.22∶1,which was higher than 1.10∶1 in term infants （P<0.05）.Conclusion From 2007 to 2018,the preterm birth rate of Shaoxing Maternal and Child Health Care Hospital increased year by year,especially in extremely and early preterm birth.