Regulatory function of long noncoding RNA MAGI2-AS3 in tumor development: a review
GU Simeng1, LI Yahui2, WANG Xiaofeng1, MO Zhe1
1. Department of Environmental Health, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051, China; 2. Hangzhou Medical College, Hangzhou, Zhejiang 310012, China; 3. Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051, China
Abstract：Long noncoding RNA (lncRNA) is closely related to the pathogenesis of cancer,representing a burgeoning field in tumor research in recent years. MAGI2-AS3, a tumor-associated lncRNA, exerts pivotal roles in epigenetics, transcription and post-transcriptional regulation. Studies have suggested that MAGI2-AS3 may be involved in multiple stages of tumor development, and has potential applications for tumor diagnosis, therapy and prognosis. This review summarizes the expression, regulatory mechanism and clinical application value of MAGI2-AS3 in common malignant tumrs, providing the reference for tumor prevention and treatment.
顾思萌, 李雅晖, 王晓峰, 莫哲. MAGI2-AS3在肿瘤发生发展中的调控机制研究进展[J]. 预防医学, 2024, 36(7): 594-597.
GU Simeng, LI Yahui, WANG Xiaofeng, MO Zhe. Regulatory function of long noncoding RNA MAGI2-AS3 in tumor development: a review. Preventive Medicine, 2024, 36(7): 594-597.
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