Epidemiological characteristics of pertussis in Huzhou City from 2012 to 2022
LIU Yan1, SHEN Jianyong2, ZHANG Chao2, SUN Xiuxiu1, WANG Yuda1, ZHENG Jiayi1, ZHANG Zizhe1
1. Department of Infectious Disease Control and Prevention, Huzhou Center for Disease Control and Prevention, Huzhou, Zhejiang 313000, China; 2. Huzhou Center for Disease Control and Prevention, Huzhou, Zhejiang 313000, China
Abstract：Objective To analyze the epidemiological characteristics of pertussis in Huzhou City, Zhejiang Province from 2012 to 2022, so as to provide insights into formulation of pertussis control measures. Methods The data of reported pertussis cases in Huzhou City from 2012 to 2022 were collected through the Infectious Disease Report Information System of Chinese Disease Prevention and Control Information System. The temporal, spatial and population distributions of pertussis cases in Huzhou City from 2012 to 2022 were analyzed using a descriptive epidemiological method. Results A total of 499 pertussis patients were reported in Huzhou City from 2012 to 2022, with mean annual reported incidence of 1.508/105, and no death was reported. The reported incidence of pertussis remained at a low level in Huzhou City from 2012 to 2021, all below 1/105, and increased to 12.625/105 in 2022. The reported incidence of pertussis appeared an overall tendency towards a rise in Huzhou City from 2012 to 2021 (Z=-29.261, P<0.001). The incidence of pertussis peaked from June to July, and a relatively higher incidence rate of pertussis was reported in Deqing (6.359/105) and Anji counties (1.725/105), while higher incidence was found among children at ages of <1 year (30.566/105), 4 years (31.896/105) and 5 years (29.485/105). Conclusions The reported incidence of pertussis was at a low level in Huzhou City from 2012 to 2021, and increased sharply in 2022. The incidence of pertussis peaked from June to July, was concentrated in Deqing and Anji counties and higher among infants under one year of age and preschool children at ages of 4 to 5 years.
[1] SEALEY K L,BELCHER T,PRESTON A.Bordetella pertussis epidemiology and evolution in the light of pertussis resurgence[J].Infect Genet Evol,2016,40:136-143. [2] 张梦,吴丹,李艺星,等.全球百日咳防控面临的挑战[J].中华流行病学杂志,2023,44(3):491-497. [3] 符剑,王跃芳,徐宝祥,等.浙江省1954—2004年百日咳流行病学分析[J].中国计划免疫,2005,11(4):279-280. [4] 刘铁诚,何寒青,周洋,等.2005—2017年浙江省百日咳流行病学分析[J].中国疫苗和免疫,2019,25(1):54-58. [5] 中华人民共和国卫生部. 百日咳诊断标准:WS 274—2007 [S]. 北京:人民卫生出版社, 2007. [6] 吴丹,郑徽,李明爽,等.中国2018—2021年百日咳流行病学特征[J].中国疫苗和免疫,2022,28(6):638-643. [7] 刘新利,樊永军.2012年陕西省铜川市百白破疫苗免疫成功率监测分析[J].疾病监测,2013,28(2):109-111. [8] DEWAN K K,LINZ B,DEROCCO S E,et al.Acellular pertussis vaccine components:today and tomorrow[J/OL].Vaccines, 2020,8(2)[2023-05-21].https://doi.org/10.3390/vaccines8020217. [9] 唐学雯,周洋,汪颖,等.浙江省百日咳报告病例流行特征分析[J].预防医学,2020,32(7):712-714. [10] 刘小乖,李亚绒,王增国,等.百日咳抗体及核酸检测技术在百日咳诊断中的作用[J].中国妇幼保健,2018,33(15):3553-3556. [11] 孙喜望,边长玲.枣庄市2013—2018年百日咳流行病学特征分析[J].中国公共卫生,2021,37(6):1008-1011. [12] 田红霞,任重,刘兰,等.2005—2019年株洲市百日咳流行特征分析[J].预防医学,2021,33(4):395-397. [13] PAIREAU J,GUILLOT S,EL-BELGHITI F A,et al.Effect of change in vaccine schedule on pertussis epidemiology in France:a modelling and serological study[J].Lancet Infect Dis,2022,22(2):265-273. [14] 张肖肖,姬艳芳,杨凯朝,等.2017—2021年河南省百日咳流行特征分析[J].河南预防医学杂志,2023,34(1):38-41. [15] HUANG H,ZHU T,GAO C,et al.Epidemiological features of pertussis resurgence based on community populations with high vaccination coverage in China[J].Epidemiol Infect,2015,143(9):1950-1956. [16] 赵薛飞,叶硕,马瑞,等.宁波市2019年健康人群百日咳血清流行病学调查[J].中华流行病学杂志,2021,42(4):638-642. [17] 黄海涛,张颖.中国百日咳的监测现状及其流行特征[J].中华实用儿科临床杂志,2017,32(22):1685-1688.
