Willingness to receive measles-containing vaccine among healthcare workers
YAN Rui1, LIN Naiheng2, LI Zhi3, SUN Xiang4, WANG Binbing5, ZHU Yao1, HE Hanqing1, LÜ Huakun1
1. Department of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051, China; 2. Xiamen University, Xiamen, Fujian 361100, China; 3. Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China; 4. Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu 210009, China; 5. Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui 230601, China
Abstract：Objective To investigate the willingness to receive measles-containing vaccine (MCV) and its influencing factors among healthcare workers in the Yangtze River Delta region, so as to provide the evidence for improving the measles-containing vaccination rate. Methods Healthcare workers were sampled from 19 medical institutions in each of Shanghai Municipality, Jiangsu Province, Zhejiang Province and Anhui Province for questionnaire surveys using a multi-stage stratified convenience sampling methods from July 2020 to March 2021. Participants' gender, age, educational level, professional title, measles-containing vaccination, awareness of MCV and willingness to receive MCV were collected, and the factors affecting the willingness to receive MCV were identified among healthcare workers using a multivariable logistic regression model. Results Totally 1 403 questionnaires were allocated, and 1 394 valid questionnaires were recovered, with an effective recovery rate of 99.36%. The respondents included 327 men and 1 067 women, with a male to female ratio of 1∶3.26, and 64.35% (897) were at ages of 31 to 50 years. There were 1 005 respondents with a bachelor degree (72.09%), 765 with middle and senior professional titles (54.88%), 676 with a history of measles-containing vaccination (48.49%), 1 176 with willingness to receive MCV (84.36%) and 218 without willingness to receive MCV due to convenience of vaccination (30.73%) and cost (19.27%). Multivariable logistic regression analysis showed that region (Zhejiang, OR=1.613, 95%CI: 1.054-2.470; Anhui, OR=2.058, 95%CI: 1.259-3.363), and no history of measles (OR=2.219, 95%CI: 1.302-3.781) were factors improving the willingness to receive MCV among healthcare workers, and hospital level (secondary, OR=0.483, 95%CI: 0.306-0.763; tertiary, OR=0.251, 95%CI: 0.160-0.394), history of measles-containing vaccination (no, OR=0.262, 95%CI: 0.172-0.399; unknown, OR=0.386, 95%CI: 0.266-0.559), and unawareness of MCV knowledge (OR=0.208, 95%CI: 0.081-0.536) were factors inhibiting the willingness to receive MCV among healthcare workers. Conclusions The willingness to receive MCV correlates with region, history of measles, hospital level, history of measles-containing vaccination and awareness of MCV knowledge among healthcare workers in the Yangtze River Delta region.
 MOSS W J.Measles[J].Lancet,2017,390(10111):2490-2502.  卢亦愚,董红军.麻疹[M].北京:人民卫生出版社,2016:121-150. LU Y Y,DONG H J.Measles[M].Beijing:People's Medical Publishing House,2016:121-150.  COHEN B,HYMAN S,ROSENBERG L,et al.Frequency of patient contact with health care personnel and visitors:implications for infection prevention[J].Jt Comm J Qual Patient Saf,2012,38(12):560-565.  NUZZO J B,MEYER D,SNYDER M,et al.What makes health systems resilient against infectious disease outbreaks and natural hazards?Results from a scoping review[J/OL].BMC Public Health,2019,19(1)[2022-07-25].https://doi.org/10.1186/s12889-019-7707-z.  苏琪茹,徐爱强,STREBEL P,等.中国消除麻疹的关键技术问题:专家解读共识[J].中国疫苗和免疫,2014,20(3):264-270,283. SU Q R,XU A Q,STREBEL P,et al.National and international experts' consensus on key technical issues of measles elimination in China[J].Chin J Vaccines Immunization,2014(3):264-270,283.  马超,郝利新,温宁,等.中国2019年麻疹流行病学特征[J].中国疫苗和免疫,2020,26(5):493-497. MA C,HAO L X,WEN N,et al.Epidemiology of measles in China,2019[J].Chin J Vaccines Immunization,2020,26(5):493-497.  严睿,周洋,邓璇,等.浙江省居民麻疹抗体水平调查[J].预防医学,2022,34(5):496-502. YAN R,ZHOU Y,DENG X,et al.Serum anti-measles antibody levels among residents in Zhejiang Province[J].Prev Med,2022,34(5):496-502.  刘艳,许二萍,张小平,等.杭州市医护人员接种麻疹疫苗的影响因素分析[J].预防医学,2018,30(1):50-54. LIU Y,XU E P,ZHANG X P,et al.Influencing factors for measles vaccine immunization among health care workers in Hangzhou[J].Prev Med,2018,30(1):50-54.  王晶晶,李淑华,汤喜红,等.上海市金山区健康成人麻疹抗体水平及含麻疹成分疫苗接种意愿分析[J].公共卫生与预防医学,2021,32(6):55-58. WANG J J,LI S H,TANG X H,et al.Analysis of measles antibody level in healthy adults in Jinshan District,Shanghai and their willingness to inoculate measles containing vaccines[J].J Public Health Prev Med,2021,32(6):55-58.  张朱佳子,李娟,索罗丹,等.北京市医务人员含麻疹成分疫苗接种率调查[J].中国疫苗和免疫,2017,23(5):580-583. ZHANG Z J Z,LI J,SUO L D,et al.Measles vaccine coverage among healthcare workers in Beijing[J].Chin J Vaccines Immunization,2017,23(5):580-583.  PATEL M K,GOODSON J L,ALEXANDER Jr.J P,et al.Progress toward regional measles elimination-worldwide,2000-2019[J].MMWR,2020,69(45):1700-1705.  BAXI R,MYTTON O T,ABID M,et al.Outbreak report:nosocomial transmission of measles through an unvaccinated healthcare worker-implications for public health[J].J Public Health,2014,36(3):375-381.  毛雯雯,王中战.北京市丰台区医务人员麻疹知信行调查研究[J].中国全科医学,2017,20(8):974-979. MAO W W,WANG Z Z.Investigation on KAP about measles among healthcare workers in Fengtai District in Beijing[J].Chin Gen Pract,2017,20(8):974-979.  马小敏,王芳,史东文,等.上海市金山区居民麻疹认知调查及疫苗接种意愿影响因素分析[J].中国初级卫生保健,2021,35(3):58-61. MA X M,WANG F,SHI D W,et al.A survey of measles awareness and influencing factors of vaccination willingness among residents in Jinshan District,Shanghai[J].Chin Prim Health Care,2021,35(3):58-61.  刘艳,许二萍,张小平,等.杭州市医护人员接种麻疹疫苗的影响因素分析[J].预防医学,2018,30(1):50-54. LIU Y,XU E P,ZHANG X P,et al.Influencing factors for measles vaccine immunization among health care workers in Hangzhou[J].Prev Med,2018,30(1):50-54.  黄振宇,朱奕,李苑,等.医务人员甲型H1N1流感疫苗接种率及其影响因素调查[J].中国热带医学,2012,12(2):230-231,234. HUANG Z Y,ZU Y,LI Y,et al.Survey of inoculation rate of influenza A(H1N1)vaccine and related factors in medical workers in Shenzhen[J].China Trop Med,2012,12(2):230-231,234.  张杭杰,丁林玲,潘雪娇,等.浙江省医疗卫生人员新型冠状病毒疫苗接种意愿和影响因素调查[J/OL].中国疫苗和免疫,2021(2021-02-18)[2022-07-25].https://doi.org/10.19914/j.CJVI.2021030. ZHANG H J,DING L L,PAN X J,et al.Willingness to receive novel coronavirus vaccine and factors influencing willingness among healthcare workers in Zhejiang province[J/OL].Chin J Vaccines Immunization,2021(2021-02-18)[2022-07-25].https://doi.org/10.19914/j.CJVI.2021030.