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预防医学  2020, Vol. 32 Issue (10): 992-995    DOI: 10.19485/j.cnki.issn2096-5087.2020.10.005
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湖州市HIV/AIDS分子网络传播簇的影响因素研究
金玫华1, 李婧1, 刘小琦1, 陈琳2, 杨中荣1
1.湖州市疾病预防控制中心,浙江 湖州 313000;
2.浙江省疾病预防控制中心
Influencing factors of molecular network transmission clusters of HIV/AIDS in Huzhou
*JIN Meihua, LI Jing, LIU Xiaoqi, CHEN Lin, YANG Zhongrong
*Huzhou Center for Disease Control and Prevention, Huzhou, Zhejiang 313000, China
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摘要 目的 分析艾滋病病毒感染者/艾滋病患者(HIV/AIDS)分子网络传播簇的影响因素,为艾滋病精准防控提供依据。方法 采用病例对照研究方法,以2017年1月―2019年6月湖州市新报告且HIV分子网络传播簇聚集性强(成簇)的HIV/AIDS病例为病例组,按照1∶4匹配同期、同社区、性别相同、年龄相近(±3岁)且HIV抗体检测阴性的居民为对照组。采用自行设计的问卷调查人口学特征、艾滋病防治知识知晓情况和艾滋病相关行为等。采用Cox回归模型分析HIV/AIDS分子网络传播簇的影响因素。结果 病例组100例,对照组400人,两组的年龄、性别、婚姻状况、户籍地和文化程度差异均无统计学意义(P>0.05)。多因素Cox回归分析结果显示,知晓艾滋病防治知识(HR=0.145,95%CI:0.059~0.352)是发生HIV/AIDS分子网络传播簇的保护因素;男男性行为者(HR=9.614,95%CI:4.645~19.901)、曾经通过网络认识同性性伴(HR=16.321,95%CI:7.016~32.968)和现患梅毒(HR=3.314,95%CI:1.073~10.232)是发生HIV/AIDS分子网络传播簇的危险因素。结论 艾滋病防治知识知晓水平、男男性行为者、通过网络认识同性性伴和现患梅毒是发生HIV/AIDS分子网络传播簇的影响因素。
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金玫华
李婧
刘小琦
陈琳
杨中荣
关键词 艾滋病分子网络传播簇男男性行为者病例对照研究    
AbstractObjective To analyze the influencing factors for the molecular network transmission clusters of HIV/AIDS, and to provide scientific evidence for the precise prevention and control of AIDS. Methods A case-control study was conducted. The HIV/AIDS cases reported from January 2017 to June 2019 in Huzhou with strong clustering of HIV molecular transmission were recruited as the case group, and the residents with same gender, similar age ( ±three years ) and HIV negative in the same community and period were matched ( 1∶4 ) as the control group. Demographic characteristics, AIDS related knowledge and sexual behaviors were collected by a questionnaire survey. The Cox regression model was used to analyze the influencing factors for HIV/AIDS molecular network transmission cluster. Results There was 100 people in the case group and 400 people in the control group, the differences between them in age, sex, marital status, place of residence and educational level were not statistically significant ( P>0.05 ) . The results of multivariate Cox regression analysis showed that awareness of AIDS related knowledge ( HR=0.145, 95%CI: 0.059-0.352 ) was a protective factor for molecular network transmission clusters of HIV/AIDS; men who have sex wth men ( MSM, HR=9.614, 95%CI: 4.645-19.901) , seeking homosexual partners through the internet (HR=16.321, 95%CI: 7.016-32.968) and having syphilis ( HR=3.314, 95%CI: 1.073-10.232 ) were risk factors for molecular network transmission clusters of HIV/AIDS. Conclusions The awareness of AIDS related knowledge, MSM, seeking homosexual partners through the internet and suffering from syphilis are the influencing factors for molecular network transmission clusters of HIV/AIDS.
Key wordsacquired immune deficiency syndrome    molecular network transmission cluster    men who have sex with men    case-control study
收稿日期: 2020-05-08      出版日期: 2020-09-30
ZTFLH:  R512.91  
基金资助:浙江省医药卫生科技计划项目(2020KY943); 湖州市科技计划项目(2019GZB04)
通信作者: 杨中荣,E-mail:yzhr91@126.com   
作者简介: 金玫华,本科,主任医师,主要从事传染病预防控制工作
引用本文:   
金玫华, 李婧, 刘小琦, 陈琳, 杨中荣. 湖州市HIV/AIDS分子网络传播簇的影响因素研究[J]. 预防医学, 2020, 32(10): 992-995.
JIN Meihua, LI Jing, LIU Xiaoqi, CHEN Lin, YANG Zhongrong. Influencing factors of molecular network transmission clusters of HIV/AIDS in Huzhou. Preventive Medicine, 2020, 32(10): 992-995.
链接本文:  
http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2020.10.005      或      http://www.zjyfyxzz.com/CN/Y2020/V32/I10/992
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