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预防医学  2023, Vol. 35 Issue (2): 93-98    DOI: 10.19485/j.cnki.issn2096-5087.2023.02.001
  论著 本期目录 | 过刊浏览 | 高级检索 |
耶尔森菌病危险因素的病例对照研究
韩俊丽1, 刘洋2, 高大维2, 孙婕2, 徐鹏鹏2, 龚天麒2, 胡颉颖2, 曹艳宏3, 吕勇1,2
1.安徽医科大学公共卫生学院,安徽 合肥 230032;
2.六安市疾病预防控制中心,安徽 六安 237010;
3.中国科学技术大学附属第一医院西区,安徽 合肥 230031
Risk factors for yersiniosis: a case-control study
HAN Junli1, LIU Yang2, GAO Dawei2, SUN Jie2, XU Pengpeng2, GONG Tianqi2, HU Jieying2, CAO Yanhong3, LÜ Yong1,2
1. School of Public Health, Anhui Medical University, Hefei, Anhui 230032, China;
2. Lu'an Center for Disease Control and Prevention, Lu'an, Anhui 237010, China;
3. West District, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui 230031, China
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摘要 目的 分析耶尔森菌病的危险因素,为预防耶尔森菌病提供依据。方法 选择2013—2021年六安市金安区城北乡和裕安区城南镇监测点诊治的耶尔森菌病病例纳入病例组,匹配病例的正常家庭成员纳入家庭对照组,并按照1∶2匹配同村、同性别和年龄相差5岁以内的居民纳入社区对照组。通过问卷调查收集人口学信息、洗手行为、饮食习惯、居住环境卫生和家禽家畜饲养情况等资料;采用条件logistic回归模型分析耶尔森菌病发病的影响因素。结果 病例组43例,年龄MQR)为45(34)岁;家庭对照组91人,年龄MQR)为36(36)岁;社区对照组86人,年龄MQR)为46(34)岁。多因素条件logistic回归分析结果显示:病例组与家庭对照组比较,习惯喝生水(OR=6.721,95%CI:1.765~25.588)和直接进食冰箱储存食物(OR=7.089,95%CI:1.873~26.829)是耶尔森菌病发病的危险因素;病例组与社区对照组比较,接触家禽家畜后不洗手(OR=50.592,95%CI:2.758~927.997)、习惯生吃蔬菜水果(OR=5.340,95%CI:1.022~27.887)、直接进食冰箱储存食物(OR=19.973,95%CI:2.118~188.336)和冰箱不清洁(OR=12.692,95%CI:1.992~80.869)是耶尔森菌病发病的危险因素;病例组与对照组(家庭+社区)比较,接触家禽家畜后不洗手(OR=4.075,95%CI:1.427~11.637)、习惯喝生水(OR=4.153,95%CI:1.331~12.957)、习惯生吃蔬菜水果(OR=4.744,95%CI:1.609~13.993)和直接进食冰箱储存食物(OR=5.051,95%CI:1.773~14.395)是耶尔森菌病发病的危险因素。结论 生吃蔬菜水果、喝生水、直接进食冰箱储存食物、冰箱不清洁和接触家禽家畜后不洗手等不良卫生习惯增加耶尔森菌病的发病风险。
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韩俊丽
刘洋
高大维
孙婕
徐鹏鹏
龚天麒
胡颉颖
曹艳宏
吕勇
关键词 耶尔森菌病病例对照研究影响因素    
AbstractObjective To investigate the risk factors for yersiniosis, so as to provide insights into prevention of yersiniosis. Methods The patients with yersiniosis admitted to the clinics in the surveillance site of Chengbei Township of Jin'an District and Chengnan Township of Yu'an District in Lu'an City from 2013 to 2021 were included as the case group, and the healthy family members matched to cases were selected as the family control group, while normal residents with a 1︰2 match in the same village, gender, and age difference within 5 years were included in the community control group. Participants' demographics, hand-washing and eating habits, living environment hygiene, poultry and livestock feeding were collected using questionnaire surveys, and factors affecting yersiniosis were identified using a multivariable conditional logistic regression model. Results There were 43 cases in the case group, with a median (interquartile range) age of 45 (34) years, 91 cases in the family control group, with a median (interquartile range) age of 36 (36) years and 86 cases in the community control group, with a median (interquartile range) age of 46 (34) years. Multivariable conditional logistic regression analysis showed that compared with the family control group, the habit of drinking unboiled water (OR=6.721, 95%CI: 1.765-25.588), and direct consumption of food stored in the refrigerator (OR=7.089, 95%CI: 1.873-26.829) were risk factors for yersiniosis in the case group; and compared with the community control group, not washing hands after contacting with poultry and livestock (OR=50.592, 95%CI: 2.758-927.997), habit of eating raw vegetables and fruits (OR=5.340, 95%CI: 1.022-27.887), direct consumption of food stored in the refrigerator (OR=19.973, 95%CI: 2.118-188.336), and unclean refrigerator (OR=12.692, 95%CI: 1.992-80.869) were risk factors for yersiniosis in the case group. Compared with the family and community control groups, not washing hands after contacting with poultry and livestock (OR=4.075, 95%CI: 1.427-11.637), habit of drinking unboiled water (OR=4.153, 95%CI: 1.331-12.957), habit of eating raw vegetables and fruits (OR=4.744, 95%CI: 1.609-13.993), and direct consumption of food stored in the refrigerator (OR=5.051, 95%CI: 1.773-14.395) were risk factors for yersiniosis in the control group. Conclusion Unhealthy habits such as eating raw vegetables and fruits, drinking unboiled water, direct consumption of food stored in the refrigerator, unclean refrigerator, and not washing hands after contacting poultry and livestock may increase the risk of yersiniosis.
Key wordsyersiniosis    case-control study    influencing factor
收稿日期: 2022-10-31      出版日期: 2023-02-21
中图分类号:  R515  
基金资助:国家科技重大专项课题(2013ZX10004-203-002)
通信作者: 吕勇,E-mail:lyong@lacdc.com.cn   
作者简介: 韩俊丽,硕士研究生在读
引用本文:   
韩俊丽, 刘洋, 高大维, 孙婕, 徐鹏鹏, 龚天麒, 胡颉颖, 曹艳宏, 吕勇. 耶尔森菌病危险因素的病例对照研究[J]. 预防医学, 2023, 35(2): 93-98.
HAN Junli, LIU Yang, GAO Dawei, SUN Jie, XU Pengpeng, GONG Tianqi, HU Jieying, CAO Yanhong, LÜ Yong. Risk factors for yersiniosis: a case-control study. Preventive Medicine, 2023, 35(2): 93-98.
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http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2023.02.001      或      http://www.zjyfyxzz.com/CN/Y2023/V35/I2/93
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