Epidemiological characteristics of coronavirus disease 2019 in Huzhou
JIN Meihua*, SHEN Jianyong, FU Yun, LIU Guangtao, LIU Yan, YANG Zhongrong, REN Feilin, XU Deshun, CHEN Liqiang, ZOU Yong, DONG Xiaolian, SHAO Bin, LIU Bin
Huzhou Center for Disease Control and Prevention,Huzhou,Zhejiang 313000,China
Abstract:Objective To learn the epidemiological characteristics of coronavirus disease 2019(COVID-19)in Huzhou,so as to provide reference for prevention and control of COVID-19. Methods All the confirmed cases of COVID-19 in Huzhou,diagnosed according to the COVID-19 Diagnosis and Treatment Plan(Sixth Version Trial)and reported from January 25 to February 7,2020,were recruited. The process of diagnosis and treatment,clinical manifestation,exposure history and close contacts were collected to analyze the epidemiological characteristics. Results On January 25,the first confirmed cases of COVID-19 in Huzhou was reported. By February 7,totally 10 confirmed cases were reported and no asymptomatic infection was found. They were all imported,including three Wuhan residents,two with a trip to Wuhan,three with a trip to Suizhou,one with a trip to Hangzhou and one with a trip to Thailand(two Wuhan passengers on the same flight). The ratio of male to female cases was 1∶1. The median age was 32 years old. Seven cases were found when they went to a doctor by themselves,and three cases were found during the quarantine. The main clinical manifestations were fever,dry cough and fatigue. The median time from onset to diagnosis was 3 days. By March 3,all the cases were discharged,with median course of 24 days. There were 312 close contacts,and all of them were released after 14 days of quarantine. Conclusions To prevent imported cases from outside and stop spread inside taken by Huzhou government was proved to be effective. All the COVID-19 cases in Huzhou were imported,mostly from Wuhan. No local cases were reported.
ZHAO S, LIN Q, RAN J, et al.Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020:A data-driven analysis in the early phase of the outbreak[J]. Int J Infect Dis,2020(92):214-217.
[4]
CHAN J F, KOK K H, ZHU Z, et al. Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan [J]. Emerg Microbes Infect, 2020, 9(1):221-236.
[5]
ZHU N, ZHANG D, WANG W, et al.A novel coronavirus from patients with pneumonia in China, 2019[J]. N Engl J Med,2020,382(8):727-733.
ZHANG J J, DONG X, CAO Y Y, et al. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan,China [J]. Allergy,2020[2020-03-26]. https://www.ncbi.nlm.nih.gov/pubmed/32077115 .DOI:10.1111/all.14238.
[11]
YANG W, CAO Q, QIN L, et al.Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19): a multi-center study in Wenzhou city, Zhejiang, China[J]. J Infect,2020,80(4):388-393.
[12]
KOORAKI S, HOSSEINY M, MYERS L,et al. Coronavirus (COVID-19) outbreak: what the department of radiology should know [J]. J Am Coll Radiol,2020[2020-03-26]. https://www.ncbi.nlm.nih.gov/pubmed/ term=Coronavirus+(COVID-19)+Outbreak%3A+What+the+Department+of+Radiology+Should+Know.DOI:10.1016/j.jacr.2020.02.008.
World Health Organization. Coronavirus disease2019(COVID-19)Situation Report-37 [EB/OL].(2020-02-26)[2020-03-26].https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200226sitrep-37-covid-19.pdf?sfvrsn=2146841e_2.
[17]
KAPATA N, IHEKWEAZU C, NTOUMI F, et al.Is the Africa prepared for tackling the COVID-19 (SARS-CoV-2) epidemic - lessons from past outbreaks, ongoing pan-African public health efforts, and implications for the future[J]. Int J Infect Dis,2020(93):233-236.
[18]
LILLIE P J, SAMSON A, LI A, et al. Novel coronavirus disease (Covid-19): the first two patients in the UK with person to person transmission[J]. J Infect,2020[2020-03-26]. https://www.ncbi.nlm.nih.gov/pubmed/ term=Novel+coronavirus+disease+(Covid-19 )%3A+the+first+two+patients+in+the+UK+with+person+to+person+transmission.DOI:10.1016/j.jinf.2020.02.020.
[19]
SPINA S, MARRAZZO F, MIGLIARI M, et al.The response of Milan's Emergency Medical System to the COVID-19 outbreak in Italy[J]. Lancet, 2020,395(10227):e49-e50.