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| Trend in disease burden of gastric cancer in Wenzhou City from 2014 to 2023 |
| WU Lihao, YE Zhenmiao, LIN Dewei, CHEN Haidong
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| Wenzhou Center for Disease Control and Prevention (Wenzhou Institute of Public Health Supervision), Wenzhou, Zhejiang 325000, China |
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Abstract Objective To investigate the trend of gastric cancer disease burden in Wenzhou City, Zhijiang Province from 2014 to 2023, so as to providing evidence for prevention and control strategies. Methods Data on incidence and mortality of gastric cancer among household registered residents in Wenzhou City from 2014 to 2023 were collected through the Wenzhou Chronic Disease Monitoring and Management Information System, and the crude incidence and crude mortality were calculated. The disease burden of gastric cancer was evaluated by calculating years of life lost (YLL), years lived with disability (YLD), and disability-adjusted life years (DALY) using the World Health Organization's disease burden methodology. Trends in YLL rate, YLD rate and DALY rate of gastric cancer from 2014 to 2023 were analyzed using the average annual percent change (AAPC). Results A total of 28 122 cases of gastric cancer and 17 080 deaths were reported in Wenzhou City from 2014 to 2023. The crude incidence and crude mortality were 34.13/105 and 20.73/105, respectively. The YYL, YLD and DALY caused by gastric cancer were 181 816.78, 53 198.41, and 235 015.198 person-years, and the YLL rate, YLD rate and DALY rate were 2.21, 0.64 and 2.85 person-years per 1 000 people, respectively. The YLL rate and DALY rate showed a downward trend (AAPC=-4.608% and -2.552%,both P<0.05), while the YLD rate showed an upward trend (AAPC=4.657%, P<0.05). The DALY rate of gastric cancer in men was 3.82 person-years per 1 000 people, and that in women was 1.83 person-years per 1 000 people, with a downward trend (AAPC=-2.924% and -1.647%, both P<0.05). The DALY rate of gastric cancer was relatively low in the 15 to <45 years age group, increased starting from the age of 45 years, and peaked in the ≥70 years age group, reaching 14.09 person-years per 1 000 peoples. The DALY rate of gastric cancer among residents aged 15 to <45 years, 45 to <70 years and ≥70 years showed a downward trend (AAPC=-3.626%, -5.450% and -4.404%, all P<0.05). Conclusions From 2014 to 2023, the DALY rate of gastric cancer in Wenzhou City demonstrated a sustained decline, primarily driven by a the loss of life years due to premature death. Males and older people continue had a heavier disease burden. It is recommended to implement targeted prevention and control measures to reduce the disease burden of gastric canceron among residents.
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Received: 14 April 2025
Revised: 13 June 2025
Published: 23 July 2025
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[1] BRAY F,LAVERSANNE M,SUNG H,et al.Global cancer statistics 2022:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA Cancer J Clin,2024,74(3):229-263.
[2] 李茁钰,刘凯,张维汉,等.全球及中国胃癌的流行病学特点及趋势:2018—2022《全球癌症统计报告》解读[J].中国普外基础与临床杂志,2024,31(10):1236-1245.
LI Z Y,LIU K,ZHANG W H,et al.Epidemiologic features and trends of gastric cancer in the world and China:interpretation of the GLOBOCAN 2018-2022[J].Chin J Bases Clin Gen Surg,2024,31(10):1236-1245.(in Chinese)
[3] HE F F,WANG S M,ZHENG R S,et al.Trends of gastric cancer burdens attributable to risk factors in China from 2000 to 2050[J/OL].Lancet Reg Health West Pac,2024,44[2025-06-13].https://doi.org/10.1016/j.lanwpc.2023.101003.
[4] HAN B F,ZHENG R S,ZENG H M,et al.Cancer incidence and mortality in China,2022[J].J Natl Cancer Cent,2024,4(1):47-53.
[5] 温州市疾病预防控制中心(温州市卫生监督所).温州市2023年癌谱报告[EB/OL].[2025-06-13].https://wjw.wenzhou.gov.cn/art/2024/4/15/art_1229419335_58916863.html.
[6] 王超. 中国生物医学文献数据库中罕见疾病数据回顾性研究[D].济南:济南大学,2015.
WANG C.Retrospective study on rare disease data in Chinese biomedical literature database[D].Jinan:University of Jinan,2015.(in Chinese)
[7] 葛阳,汪俞威,宇传华.利用DisMod软件分析江干区三种癌症的疾病负担[J].中国卫生统计,2013,30(6):910-912.
GE Y,WANG Y W,YU C H.Using DisMod software to analyze the disease burden of three kinds of cancers in Jianggan District[J].Chin J Health Stat,2013,30(6):910-912.(in Chinese)
[8] KRUIJSHAAR M E,BARENDREGT J J,HOEYMANS N.The use of models in the estimation of disease epidemiology[J].Bull World Health Organ,2002,80(8):622-628.
[9] 阎月明,刘阳,江国虹,等.基于DisMod校正法对天津市2007—2015年发病监测系统中急性心肌梗死发病报告完整性判断[J].中国公共卫生,2019,35(7):861-865.
YAN Y M,LIU Y,JIANG G H,et al.Completeness of acute myocardial infarction incidence reports in Chronic Disease Incidence Surveillance System of Tianjin city,2007 to 2015:an evaluation using DisMod software[J].Chin J Public Health,2019,35(7):861-865.(in Chinese)
[10] 曾令乾. 慢性病疾病负担的计算及应用[D].合肥:中国科学技术大学,2019.
ZENG L Q.Calculation and application of chronic disease burden[D].Hefei:University of Science and Technology of China,2019.(in Chinese)
[11] YANG W J,ZHAO H P,YU Y,et al.Updates on global epidemiology,risk and prognostic factors of gastric cancer[J].World J Gastroenterol,2023,29(16):2452-2468.
[12] 赵琳,蒋龙艳,徐斌,等.南宁市五种主要恶性肿瘤发病率分析[J].预防医学,2025,37(2):135-138.
ZHAO L,JIANG L Y,XU B,et al.Incidence characteristics of five major malignant tumors in Nanning City[J].China Prev Med J,2025,37(2):135-138.(in Chinese)
[13] 郑纲,张沛绮,陈茜,等.温州市鹿城区居民慢性病相关行为危险因素现况调查[J].中国农村卫生事业管理,2018,38(11):1447-1449.
ZHENG G,ZHANG P Q,CHEN X,et al.Risk factors of chronic disease behavior among residents in Lucheng District,Wenzhou[J].Chin Rural Health Serv Adm,2018,38(11):1447-1449.(in Chinese)
[14] 杜君彦,潘杰,周晴接,等.2013—2020年浙江温州地区幽门螺杆菌耐药情况分析[J].中国全科医学,2023,26(7):825-829.
DU J Y,PAN J,ZHOU Q J,et al.The Helicobacter Pylori antibiotic resistance in Wenzhou,Zhejiang from 2013 to 2020[J].Chin Gen Pract,2023,26(7):825-829.(in Chinese)
[15] 曾玲,胥馨尹,谭大华,等.2015—2019年四川省肿瘤登记地区胃癌发病与死亡变化趋势分析[J].中国肿瘤,2024,33(7):535-541.
ZENG L,XU X Y,TAN D H,et al.Trends in incidence and mortality of gastric cancer in Sichuan cancer registration areas from 2015 to 2019[J].China Cancer,2024,33(7):535-541.(in Chinese)
[16] 浙江省民政厅. 2023年浙江省老年人口和老龄事业统计公报[EB/OL].[2025-06-13].https://mzt.zj.gov.cn/art/2024/8/20/art_1229776733_5351453.html. |
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