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| Analysis of thyroid hormone indicators among interventionaland diagnostic radiologists |
| ZHANG Qun1, WANG Aihong1, YU Xiaopin2, YING Zhengju1, QU Lingyan1, ZHANG Dandan1
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1. Department of Enironmental and Occupational Health Promotion, Ningbo Center for Disease Control and Prevention, Ningbo, Zhejiang 315010, China;
2. Ningbo First Hospital, Ningbo, Zhejiang 315000, China |
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Abstract Objective To learn the levels of thyroid hormone indicators among interventional and diagnostic radiologists, so as to provide insights into occupational health monitoring of radiologists. Methods Demographic information, body mass index (BMI), thyroid hormone indicators and cumulative individual doses over 5 years among interventional and diagnostic radiologists were collected through the personal dosimetry monitoring database of Ningbo Center for Disease Control and Prevention and the Occupational Health Examination Center of a tertiary hospital in Ningbo City. The thyroid hormone indicators of different job types and cumulative individual doses over 5 years were analyzed, and factors affecting the thyroid hormone indicators were identified using a multivariable ordinal logistic regression model. Results There were 159 interventional and 159 diagnostic radiologists included, and the proportions of abnormal thyroid hormone indicators were 9.43% and 12.26%, respectively, with no statistically significant difference (P>0.05). The levels of triiodothyronine and free triiodothyronine in interventional radiologists were lower than those in diagnostic radiologists [(1.54±0.41) vs. (1.68±0.34) nmol/L, (5.13±1.07) vs. (5.55±0.87) pmol/L; both P<0.05]. The levels of triiodothyronine and free triiodothyronine were significantly different among radiologists with cumulative individual doses over 5 years of <1.5 mSv, 1.5-<3.0 mSv and ≥3.0 mSv [(1.69±0.31), (1.69±0.40) vs. (1.52±0.41) nmol/L, (5.60±0.83), (5.32±0.94) vs. (5.14±1.09) pmol/L; both P<0.05]. Multivariable ordinal logistic regression analysis identified BMI (<18.5 kg/m2, OR=0.111, 95%CI: 0.028-0.436) and cumulative individual doses over 5 years (<1.5 mSv, OR=6.259, 95%CI: 2.368-16.547) as the factors affecting triiodothyronine, and job types (diagnostic radiologists, OR=3.171, 95%CI: 1.529-6.574), BMI (18.5-<24.0 kg/m2, OR=0.393, 95%CI: 0.184-0.842), and gender (men, OR=3.449, 95%CI: 1.294-9.190) as the factors affecting free triiodothyronine. Conclusion Occupational exposure has a certain impact on the thyroid hormone indicators among interventional and diagnostic radiologists, and the main influencing factors include BMI, radiation dose, job type and gender.
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Received: 07 September 2023
Revised: 30 November 2023
Published: 21 February 2024
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[1] 石瑞芬,董雪梅,陈松根,等.某市医用放射工作人员甲状腺功能调查与分析[J].中国辐射卫生,2018,27(1):28-30.
[2] 吕扬阳,王志斌,张洋,等.医用电离辐射对放射工作人员甲状腺功能及结节的影响[J].职业与健康,2018,34(4):446-449.
[3] 高锦,瞿述根,沈月平,等.低剂量电离辐射对放射工作人员甲状腺功能影响的Meta分析[J].中华放射医学与防护杂志,2017,37(10):777-785.
[4] CHAKER L,BIANCO A C,JONKLAAS J,et al.Hypothyroidism[J].Lancet,2017,390(10101):1550-1562.
[5] ALAWNEH K,ALSHEHABAT M,AL-EWAIDAT H,et al.Asymptomatic effect of occupational radiation exposure on thyroid gland hormones and thyroid gland ultrasonographic abnormalities[J].J Clin Med,2018,7(4):1-5.
[6] LUNA-SÁNCHEZ S,CAMPO M D,MORÁN J V,et al.Thyroid function in health care workers exposed to ionizing radiation[J].Health Phys,2019,117(4):403-407.
[7] LITTLE M P,LIM H,FRIESEN M C,et al.Assessment of thyroid cancer risk associated with radiation dose from personal diagnostic examinations in a cohort study of US radiologic technologists,followed1983-2014[J/OL].BMJ Open,2018,8(5)[2023-11-30].https://doi.org/10.1136/bmjopen-2018-021536.
[8] 郭佳娣,郦依华,俞顺飞,等.2011—2019年浙江省11家省级医院放射工作人员外照射个人剂量监测结果分析[J].预防医学,2021,33(9):948-950.
[9] WONG Y S,CHENG Y Y,CHENG T J,et al.The relationship between occupational exposure to low-dose ionizing radiaton and changes in thyroid hormones in hospital workers[J].Epidemiology,2019,30(Suppl.1):S32-S38.
[10] GUO Q S,RUAN P,HUANG W X,et al.Occupational radiation exposure and changes in thyroid hormones in a cohort of Chinese medical radiation workers[J].Biomed Environ Sci,2021,34(4):282-289.
[11] 杨勇,王强,杨陆婷,等.某市部分放射工作人员甲状腺情况及影响因素分析[J].中华劳动卫生职业病杂志,2022,40(2):113-116.
[12] 戴霞云,罗永斌,刘安生,等.武汉市放射工作人员甲状腺功能的影响因素分析[J].预防医学,2023,35(5):406-409.
[13] CIOFFI D L,FONTANA L,LESO V,et al.Low dose ionizing radiation exposure and risk of thyroid functional alterations in healthcare workers[J/OL].Eur J Radiol,2020,132[2023-11-30].https://doi.org/10.1016/j.ejrad.2020.109279.
[14] 王莉莉,刘继文.低剂量电离辐射对放射工作人员甲状腺功能的影响[J].中国工业医学杂志,2021,34(2):147-148.
[15] 中华人民共和国国家卫生健康委员会.职业性放射性甲状腺疾病诊断:GBZ 101—2020[S/OL].[2023-11-30].https://max.book118.com/html/2020/1202/6130120234003030.shtm. |
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