|
|
|
| Factors affecting thyroid nodules among residents in Dinghai District |
| XU Haodi1, CHEN Yan1, LI Peng2, WANG Yuchao2
|
1. Department of Food Safety and Nutrition Hygiene, Zhoushan Center for Disease Control and Prevention, Zhoushan, Zhejiang 316021, China;
2. Zhoushan Center for Disease Control and Prevention,Zhoushan, Zhejiang 316021, China |
|
|
|
|
Abstract Objective To investigate the detection of thyroid nodules and its influencing factors among residents in Dinghai District, Zhoushan City, Zhejiang Province, so as to provide insights into formulation of thyroid nodule control measures. Methods Residents who were at ages of 18 years and older and had lived for 5 years or more in Dinghai District were sampled using a multi-stage stratified random sampling method from July to September 2022. Basic information was collected using a basic personal information registration form, the height, body weight, waist circumference and blood pressure were measured, and fasting blood glucose, low-density lipoprotein cholesterol (LDL-C) and urinary iodine were detected. Ultrasound examination of the thyroid gland in the neck was performed using a color ultrasound device; and the detection of thyroid nodules was analyzed and standardized by the population of the Sixth National Population Census in 2010. Factors affecting thyroid nodules using a multivariable logistic regression model. Results A total of 434 residents were included, with a mean age of (49.97±14.74) years. There were 151 males (34.79%) and 283 females (65.21%). Thyroid nodules were detected in 232 cases, with a crude detection rate of 53.46% and a standardized detection rate of 35.69%, and the crude detection rate was 19.82% for solitary nodules and 33.64% for multiple nodules. Multivariable logistic regression analysis identified gender (female, OR=2.355, 95%CI: 1.520-3.647), age (40 to 59 years, OR=2.344, 95%CI: 1.416-3.878; 60 years and older, OR=5.157, 95%CI: 2.869-9.272), high level of LDL-C (OR=1.706, 95%CI: 1.065-2.734) as factors affecting thyroid nodules. Conclusion The risk of thyroid nodules is higher among residents who are female, are 40 years and older and have high levels of LDL-C in Dinghai District.
|
|
Received: 07 October 2023
Revised: 08 January 2024
Published: 21 February 2024
|
|
|
|
|
|
[1] LI Y H,JIN C,LI J,et al.Prevalence of thyroid nodules in China:a health examination cohort-based study[J].Front Endocrinol(Lausanne),2021,12:1-9.
[2] ALEXANDER E K,CIBAS E S.Diagnosis of thyroid nodules[J].Lancet Diabetes Endocrinol,2022,10(7):533-539.
[3] 赖晓英,欧阳平,朱宏,等.甲状腺结节检出情况及影响因素:10年309 576例体检人群分析[J].南方医科大学学报,2020,40(2):268-273.
[4] ZHOU J Q,YIN L X,WEI X,et al.2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules:the C-TIRADS[J].Endocrine,2020,70(2):256-279.
[5] 范佳莹,李向明,陈长喜,等.宁波市中老年人甲状腺结节患病状况调查[J].预防医学,2016,28(5):495-497.
[6] SHIN J,KIM M H,YOON K H,et al.Relationship between metabolic syndrome and thyroid nodules in healthy Koreans[J].Korean J Intern Med,2016,31(1):98-105.
[7] 中华人民共和国国家卫生和计划生育委员会.尿中碘的测定第1部分:砷铈催化分光光度法:WS/T 107.1—2016[S].2016.
[8] 中华人民共和国国家卫生计划和计划生育委员会.成人体重判定:WS/T 428—2013[S].2013.
[9] 李晓慧,徐岐山,王卫芳.太原地区健康体检人群甲状腺结节患病率及危险因素分析[J].中国地方病防治杂志,2018,33(2):121-124.
[10] 郭才娟,沈平.护理干预对中老年临界高血压患者的效果分析[J].中国社区医师,2015(29):123-124.
[11] ZHU Y,TONG M K,WANG Y Y,et al.Prevalence of thyroid nodules and its association with water iodine among Chinese men and women[J].Environ Res,2022,212:1-6.
[12] ITO Y,AMINO N,MIYAUCHI A.Thyroid ultrasonography[J].World J Surg,2010,34(6):1171-1180.
[13] 易井萍,戴亚欣,张永利,等.舟山市居民碘营养水平及甲状腺结节患病率调查[J].预防医学,2018,30(6):600-602.
[14] 中华人民共和国国家卫生健康委员会.碘缺乏地区和适碘地区的划定:WS/T 669—2020[S].2020.
[15] 林启,周晶耀,张永利.舟山市海岛人群碘营养状况调查[J].预防医学,2012,24(8):42-43,51.
[16] 闫艳芳. 雌、雄激素和维生素D及其受体在甲状腺结节患者血清及甲状腺组织中的水平[D].石家庄:河北医科大学,2015.
[17] 杨波,曹冰,韩飞舟.军事飞行人员甲状腺结节检出情况及其与血脂水平的相关性分析[J].空军航空医学,2023,40(3):233-237.
[18] 姚玲. 甲状腺结节发生与糖脂代谢水平的相关性[J].当代医学,2021,27(35):12-15.
[19] OBRADOVIC M,SUDAR-MILOVANOVIC E,SOSKIC S,et al.Leptin and obesity:role and clinical implication[J].Front Endocrinol(Lausanne),2021,12:1-14.
[20] 段荣华. 脑梗死患者血清瘦素水平及意义[J].吉林医学,2014,35(14):2987-2989.
[21] LIU J F,WANG C G,TANG X L,et al.Correlation analysis of metabolic syndrome and its components with thyroid nodules[J].Diabetes Metab Syndr Obes,2019,30(12):1617-1623. |
|
|
|
