|
|
|
| Risk factors for cardiometabolic multimorbidity: a meta-analysis |
| JIA Ming1, PENG Juyi2, LIU Xingyu1, LIU Yudan1, ZHAO Hua1
|
1. School of Nursing, Shanxi University of Chinese Medicine, Jinzhong, Shanxi 030619, China;
2. Shanxi Bethune Hospital, Taiyuan, Shanxi 030032, China |
|
|
|
|
Abstract Objective To systematically evaluate risk factors for cardiometabolic multimorbidity (CMM), so as to provide the evidence for formulating CMM prevention and control strategies. Methods Publications pertaining to the risk factors for CMM were retrieved from databases, including SinoMed, CNKI, Wanfang Data, VIP, PubMed and Cochrane Library from inception to March 31, 2023. Meta-analysis was performed using the software RevMan 5.4 and Stata 16.0, and sensitivity analysis was performed using the leave-one-out method. The publication bias was evaluated using Egger's test. Results Totally 494 publications were screened, and 20 publications were included in the final analysis, including 13 cohort studies (covering 1 940 000 participants) and 7 cross-sectional studies (covering 13 000 000 participants). Meta-analysis revealed that female (OR=1.54, 95%CI: 1.40-1.71), middle age (OR=3.80, 95%CI: 3.33-4.34), elderly (OR=2.82, 95%CI: 1.48-5.37), urban resident (OR=1.41, 95%CI: 1.27-1.57), higher education level (OR=2.01, 95%CI: 1.35-3.01), higher economic level (OR=1.21, 95%CI: 1.16-1.25), overweight (OR=1.92, 95%CI: 1.64-2.26), obesity (OR=3.01, 95%CI: 2.30-3.93), central obesity (OR=1.70, 95%CI: 1.12-2.56), smoking (OR=1.27, 95%CI: 1.07-1.51), alcohol consumption (OR=1.27, 95%CI: 1.01-1.59), irregular diet (OR=1.10, 95%CI: 1.02-1.18), insufficient intake of vegetables and fruits (OR=1.12, 95%CI: 1.07-1.17), lack of sleep at night (OR=1.17, 95%CI: 1.08-1.27), and depression (OR=1.50, 95%CI: 1.33-1.69) were risk factors for CMM. Sensitivity analysis of effects of central obesity and alcohol consumption were not robust. No publication bias was examined by Egger's test. Conclusion Female, middle age, elderly, urban resident, higher education level, higher economic level, overweight, obesity, central obesity, smoking, alcohol consumption, irregular diet, insufficient intake of vegetables and fruits, lack of sleep at night and depression are risk factors for CMM.
|
|
Received: 16 June 2023
Revised: 21 July 2023
Published: 06 September 2023
|
|
|
|
|
|
[1] 韩雨廷,孙至佳,吕筠,等.生活方式与心血管代谢性共病关联研究进展[J].中华疾病控制杂志,2021,25(3):266-270.
[2] CHENG X J,MA T Q,OUYANG F Y,et al.Trends in the prevalence of cardiometabolic multimorbidity in the United States,1999-2018[J/OL].Int J Environ Res Public Health,2022,19(8)[2023-07-21].https://doi.org/10.3390/ijerph19084726.
[3] DOVE A,GUO J,MARSEGLIA A,et al.Cardiometabolic multimorbidity accelerates cognitive decline and dementia progression[J].Alzheimers Dement,2023,19(3):821-830.
[4] FAN J N,SUN Z J,YU C Q,et al.Multimorbidity patterns and association with mortality in 0.5 million Chinese adults[J].Chin Med J(Engl),2022,135(6):648-657.
[5] STANG A.Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses[J].Eur J Epidemiol,2010,25(9):603-605.
[6] 曾宪涛,刘慧,陈曦,等.Meta分析系列之四:观察性研究的质量评价工具[J].中国循证心血管医学杂志,2012,4(4):297-299.
[7] KIVIMAKI M,KUOSMA E,FERRIE J E,et al.Overweight,obesity,and risk of cardiometabolic multimorbidity:pooled analysis of individual-level data for 120 813 adults from 16 cohort studies from the USA and Europe[J].Lancet Public Health,2017,2(6):277-285.
[8] SINGH-MANOUX A,FAYOSSE A,SABIA S,et al.Clinical,socioeconomic,and behavioural factors at age 50 years and risk of cardiometabolic multimorbidity and mortality:a cohort study[J/OL].PLoS Med,2018,15(5)[2023-07-21].https://doi.org/10.1371/journal.pmed.1002571.
[9] FENG L,JEHAN I,DE SILVA H A,et al.Prevalence and correlates of cardiometabolic multimorbidity among hypertensive individuals:a cross-sectional study in rural South Asia-Bangladesh,Pakistan and Sri Lanka[J/OL].BMJ Open,2019,9(9)[2023-07-21].http://dx.doi.org/10.1136/bmjopen-2019-030584.
[10] SAKAKIBARA B M,OBEMBE A O,ENG J J.The prevalence of cardiometabolic multimorbidity and its association with physical activity,diet,and stress in Canada:evidence from a population-based cross-sectional study[J].BMC Public Health,2019,19(1):1-9.
[11] JEONG D,KIM J,LEE H,et al.Association of cardiometabolic multimorbidity pattern with dietary factors among adults in South Korea[J].Nutrients,2020,12(9):2730-2745.
[12] HAN Y,HU Y,YU C,et al.Lifestyle,cardiometabolic disease,and multimorbidity in a prospective Chinese study[J].Eur Heart J,2021,42(34):3374-3384.
[13] LU Y Q,LIU S Y,QIAO Y N,et al.Waist-to-height ratio,waist circumference,body mass index,waist divided by height0.5 and the risk of cardiometabolic multimorbidity:a national longitudinal cohort study[J].Nutr Metab Cardiovasc Dis,2021,31(9):2644-2651.
[14] SEWPAUL R,MBEWU A D,FAGBAMIGBE A F,et al.Prevalence of multimorbidity of cardiometabolic conditions and associated risk factors in a population-based sample of South Africans:a cross-sectional study[J/OL].Public Health Pract(Oxf),2021,2[2023-07-21].https://doi.org/10.1016/j.puhip.2021.100193.
[15] 黄紫婷,罗颜,苏鹤轩,等.中国老年心血管代谢性共病与抑郁症状的关系[J].中国慢性病预防与控制,2021,29(9):644-648.
[16] GONG L,MA T Q,HE L F,et al.Association between single and multiple cardiometabolic diseases and depression:a cross-sectional study of 391 083 participants from the UK Biobank[J/OL].Front Public Health,2022[2023-07-15].https://doi.org/10.3389/fpubh.2022.904876.
[17] LUO H,ZHANG Q,YU K,et al.Long-term exposure to ambient air pollution is a risk factor for trajectory of cardiometabolic multimorbidity:a prospective study in the UK Biobank[J/OL].EBioMedicine,2022,84[2023-07-21].https://doi.org/10.1016/j.ebiom.2022.104282.
[18] QIAO Y N,DING Y,LI G C,et al.Role of depression in the development of cardiometabolic multimorbidity:findings from the UK Biobank study[J].J Affect Disord,2022,319:260-266.
[19] YANG L,LUO Y,HE L F,et al.Shift work and the risk of cardiometabolic multimorbidity among patients with hypertension:a prospective cohort study of UK Biobank[J/OL].J Am Heart Assoc,2022,11(17)[2023-07-21].https://doi.org/10.1161/JAHA.122.025936.
[20] ZHANG H H,DUAN X Y,RONG P X,et al.Effects of potential risk factors on the development of cardiometabolic multimorbidity and mortality among the elders in China[J/OL].Front Cardiovasc Med,2022,9[2023-07-21].https://doi.org/10.3389/fcvm.2022.966217.
[21] OTIENO P,ASIKI G,WEKESAH F,et al.Multimorbidity of cardiometabolic diseases:a cross-sectional study of patterns,clusters and associated risk factors in Sub-Saharan Africa[J/OL].BMJ Open,2023,13(2)[2023-07-21].http://dx.doi.org/10.1136/bmjopen-2022-064275.
[22] QIN K,BAI S G,CHEN W Q,et al.Association of comorbid depression and obesity with cardiometabolic multimorbidity among middle-aged and older Chinese adults:a cohort study[J/OL].Arch Gerontol Geriatr,2023,107[2023-07-21].https://doi.org/10.1016/j.archger.2022.104912.
[23] ZHEN S,LI Q,LIAO J,et al.Associations between household solid fuel use,obesity,and cardiometabolic health in China:a cohort study from2011 to 2018[J/OL].Int J Environ Res Public Health,2023,20(4)[2023-07-21].https://doi.org/10.3390/ijerph20042826.
[24] ZOU H T,ZHANG S Y,CAI M,et al.Ambient air pollution associated with incidence and progression trajectory of cardiometabolic diseases:a multi-state analysis of a prospective cohort[J/OL].Sci Total Environ,2023,862[2023-07-21].https://doi.org/10.1016/j.scitotenv.2022.160803.
[25] 郭丹,丁若溪,何平.中国老年人心血管代谢性共病的患病情况及影响因素研究[J].中国慢性病预防与控制,2023,31(2):101-105.
[26] LUO Y,HE L F,MA T Q,et al.Associations between consumption of three types of beverages and risk of cardiometabolic multimorbidity in UK Biobank participants:a prospective cohort study[J].BMC Med,2022,20:1-13.
[27] CANOY D,TRAN J,ZOTTOLI M,et al.Association between cardiometabolic disease multimorbidity and all-cause mortality in 2 million women and men registered in UK general practices[J].BMC Med,2021,19:1-10.
[28] ADEDINSEWO D A,POLLAK A W,PHILLIPS S D,et al.Cardiovascular disease screening in women:leveraging artificial intelligence and digital tools[J].Circ Res,2022,130(4):673-690.
[29] DI ANGELANTONIO E,KAPTOGE S,WORMSER D,et al.Association of cardiometabolic multimorbidity with mortality[J].JAMA,2015,314(1):52-60.
[30] HE L F,MA T Q,CHENG X J,et al.The association between sleep characteristics and the risk of all-cause mortality among individuals with cardiometabolic multimorbidity:a prospective study of UK Biobank[J].J Clin Sleep Med,2023,19(4):651-658. |
|
|
|
