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| Association, pathological mechanisms, prevention and control strategies of diabetes and vascular dementia: a review |
| ZHANG Danping, XU Lingmiao
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| Dementia Rehabilitation Center, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang 310012, China |
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Abstract The incidence rate of vascular dementia is increasing year by year, and there is still no effective treatment at present, so it is very important to reduce the risk of developing vascular dementia. Research shows that diabetes is associated with vascular dementia. Based on the research literature related to diabetes and vascular dementia from January 1995 to April 2023, This article reviews the relationship between diabetes and vascular dementia, pathological mechanism and prevention and control strategies. It is found that diabetes can promote the occurrence and development of vascular dementia by inducing cerebrovascular disease, oxidative stress and inflammatory reaction, using hypoglycemic drugs, removing the incentives of cerebrovascular disease, maintaining the stability of blood-brain barrier and adhering to a healthy lifestyle are the main measures for the prevention and control of vascular dementia at this stage. Future research needs to further explore the mechanism of vascular dementia induced by diabetes, and seek economic and effective prevention targets.
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Received: 24 April 2023
Revised: 28 June 2023
Published: 17 July 2023
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