|
|
|
| Predictive value of lipid accumulation product and visceral fat index for metabolic syndrome among middle-aged and elderly populations |
| WANG Qianqian, QU Shuna, YU Shaoyi, ZHANG Hongjie
|
| Department of Non-communicable Disease Control and Prevention, Yantai Center for Disease Control and Prevention, Yantai, Shandong 264003, China |
|
|
|
|
Abstract Objective To investigate the value of lipid accumulation product (LAP) and visceral fat index (VAI) for prediction of metabolic syndrome (MS). Methods Based on the 2018 Survey on Chronic Diseases and Risk Factors in Yantai City of Shandong Province, residents at ages of 45 years and older were sampled, and subjects' age, disease history, waist circumstance (WC), body mass index (BMI), blood pressure and blood lipid were collected to calculate LAP and VAI. MS was diagnosed with the a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity (JIS definition) and the recommended criteria proposed by the Chinese Diabetes Society (CDS) of Chinese Medical Association (CDS criteria), and the values of LAP and VAI for MS screening were evaluated using the receiver operating characteristic (ROC) curve analysis. Results Totally 9 366 subjects were enrolled, including 4 340 men (46.34%) and 5 026 women (53.66%), and had a mean age of (54.49±9.73) years. According to the CDS criteria, the prevalence of MS was 24.58%, and LAP and VAI showed areas under the ROC curve (AUC) of 0.837 (95%CI: 0.828-0.846) and 0.751 (95%CI: 0.739-0.762), sensitivities of 78.82% and 63.31% and optimal cut-off values of 44.64 and 1.86 for screening of MS. According to the JIS definition, the prevalence of MS was 35.26%, and LAP and VAI showed AUC values of 0.842 (95%CI: 0.834-0.850) and 0.790 (95%CI: 0.780-0.800), sensitivities of 75.73% and 68.42% and optimal cut-off values of 42.01 and 1.67 for screening of MS. Conclusions Both LAP and VAI are effective for screening MS among middle-aged and elderly residents, and LAP presents a higher accuracy than VAI.
|
|
Received: 28 April 2022
Revised: 23 June 2022
Published: 08 September 2022
|
|
|
|
|
|
[1] 何宇纳,赵文华,赵丽云,等.中国2010—2012年成年人代谢综合征流行特征[J].中华流行病学杂志,2017,38(2):212-215.
HE Y N,ZHAO W H,ZHAO L Y,et al.Prevalence of metabolic syndrome in Chinese adults in 2010-2012[J].Chin J Epidemiol,2017,38(2):212-215.
[2] 李文敏,高凯.2014—2017年我国居民代谢综合征患病率的meta分析[J].慢性病学杂志,2018,19(11):1476-1480.
LI W M,GAO K.The prevalence of metabolic syndrome in China from 2014 to 2017:a meta-analysis[J].Chronic Pathematol J,2018,19(11):1476-1480.
[3] 孙焕珍,金来润,左翔,等.社区体检人群代谢综合征患病情况及相关影响因素的调查分析[J].中华疾病控制杂志,2017,21(5):465-468.
SUN H Z,JIN L R,ZUO X,et al.Study on the prevalence of metabolic syndrome and its influencing factors in a community medical check-up crowd[J].Chin J Dis Control Prev,2017,21(5):465-468.
[4] 朱雯,李辉,王永,等.宁波市居民代谢综合征现况调查[J].预防医学,2017,29(7): 653-659.
ZHU W,LI H,WANG Y,et al.A study on the prevalence of metabolic syndrome and related factors among residents in Ningbo[J].Prev Med,2017,29(7):653-659.
[5] 刘晨,张黎军.新型体脂指数脂质蓄积指数和内脏脂肪指数的相关研究进展[J].中国糖尿病杂志,2016,24(11):1032-1035.
LIU C,ZHANG L J.Research progress of new type body fat indexes of lipid accumulation product index and visceral adiposity index[J].Chin J Diabetes,2016,24(11):1032-1035.
[6] 蔡瑞雪,巢健茜,孔玲燕,等.四种代谢综合征诊断标准在老年人中的适用性比较[J].中华疾病控制杂志,2019,23(2):146-149.
CAI R X,CHAO J X,KONG L Y,et al.Comparison of four different metabolic syndrome diagnostic criteria among the elderly in Nanjing[J].Chin J Dis Control Prev,2019,23(2):146-149.
[7] ALBERTI K G,ECKEL R H,GRUNDY S M,et al.Harmonizing the metabolic syndrome:a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute;American Heart Association; World Heart Federation; International Atherosclerosis Society;and International Association for the Study of Obesity[J].Circulation,2009,120(16):1640-1645.
[8] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2020 年版)[J].中华糖尿病杂志,2021,13(4):315-409.
Chinese Diabetes Society.Guidelines for the prevention and control of type 2 diabetes in China (2020 editon)[J].Chin J Diabetes Mellit,2021,13(4):315-409.
[9] 中国成人血脂异常防治指南制订联合委员会.中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-419.
Joint Committee for Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults.Chinese guidelines on prevention and treatment of dyslipidemia in adults[J].Chin J Cardiol,2007,35(5):390-419.
[10] 王超伟,张洁,梁屹,等.石家庄市中老年代谢综合征现状及其相关因素分析的调查研究[J].中国糖尿病杂志,2013,21(5):398-401.
WANG C W,ZHANG J,LIANG Y,et al.Epidemiological investigation on metabolic syndrome in middle-aged and old people in Shijiazhuang and analysts on its influence factors[J].Chin J Diabetes,2013,21(5):398-401.
[11] 李望. 成都市中老年人代谢综合征患病情况及其危险因素分析[J].中国公共卫生,2021,37(1):40-43.
LI W.Prevalence and risk factors of metabolic syndrome among middle-aged and elderly people in Chengdu city[J].Chin J Public Health,2021,37(1):40-43.
[12] 黄长珍,卢章云,胡引闹,等.东阳市居民代谢综合征患病现况调查[J].预防医学,2016,28(5):490-492.
HUANG C Z,LU Z Y,HU Y N,et al.The prevalence of metabolic syndrome among residents in Dongyang City[J].Prev Med,2016,28(5):490-492.
[13] MOTAMED N,KHONSARI M R,RABIEE B,et al.Discriminatory ability of visceral adiposity index(VAI)in diagnosis of metabolic syndrome:a population based study[J].Exp Clin Endocrinol Diabetes,2017,125(3):202-207.
[14] CHENG Y L,WANG Y J,LAN K H,et al.Fatty liver index and lipid accumulation product can predict metabolic syndrome in subjects without fatty liver disease[J/OL].Gastroenterol Res Pract,2017[2022-06-23].https://doi.org/10.1155/2017/9279836.
[15] 陆春华,仇琦,董爱丽,等.上海郊县社区中老年人代谢综合征调查及影响因素分析[J].中华老年心脑血管病杂志,2021,23(10):1095-1096.
LU C H,QIU Q,DONG A L,et al.Prevalence of metabolic syndrome and its influencing factors among the middle aged and old populations in suburban communities of Shanghai[J].Chin J Geriatr Heart Brain Vessel Dis,2021,23(10):1095-1096.
[16] 蒋剑波,林玲萍,杜丽云,等.杭州市中年人群三种膳食模式与代谢综合征的关系研究[J].预防医学,2018,30(12): 1222-1226.
JIANG J B,LIN L P,DU L Y,et al.Association of three dietary patterns with metabolic syndrome in the middle-aged population in Hangzhou[J].Prev Med,2018,30(12):1222-1226.
[17] 喻森海,潘飞霞,顾杭杰,等.农村代谢综合征患者强化生活方式干预效果评价[J].预防医学,2017,29(12):1193-1198.
YU S H,PAN F X,GU H J,et al.Effectiveness evaluation of intensive lifestyle intervention on rural residents with metabolic syndrome[J].Prev Med,2017,29(12):1193-1198. |
|
|
|
