|
|
|
| Association between frailty and lifestyle factors among middle-aged and elderly populations |
| LIN Jingjing1, DU Yushan2, LIANG Mingbin1, CHEN Xiangyu1, HE Qingfang1, XU Hui3, QIN Jiasheng3, LU Feng1, WANG Lixin1, ZHONG Jieming1, FANG Le1
|
1. Department of Non-communicable Disease Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051, China;
2. Peking University, Beijing 100191, China;
3. Changxing Center for Disease Control and Prevention, Changxing, Zhejiang 313199, China |
|
|
|
|
Abstract Objective To examine the correlation between frailty and lifestyle factors among middle-aged and elderly populations, so as to provide insights into the management of frailty among middle-aged and elderly populations. Methods Middle-aged and elderly residents at ages of 45 ot 69 years were recruited using the convenient sampling method from seven townships in Changxing County of Zhejiang Province from 2019 to 2020. The demographic characteristics and lifestyle factors were collected using questionnaires, and the frailty was measured using the Chinese version of Tilburg Frailty Indicator ( TFI ). Factors affecting frailty were identified among middle-aged and elderly populations using the multivariable logistic regression model. Results A total of 7 170 residents were surveyed, including 2 780 males ( 38.77% ) and 4 390 females ( 61.23% ), which had a median age of 56 (interquartile range, 10) years. The median frailty score was 2 (interquartile range, 3 ) among the study subjects, and the median frailty score was 2 ( interquartile range, 2 ) among residents at ages of 45 to 59 years, and 2 (interquartile range, 3) among residents at ages of 60 to 69 years. The overall detection of frailty was 16.07%, and the detection of frailty was 13.52% among subjects at ages of 45 to 59 years and 21.01% among subjects at ages of 60 to 69 years. Multivariable logistic regression analysis identified physical activity ( OR=0.826, 95%CI: 0.719-0.949 ) and sleep quality ( OR: 3.376-11.493, 95%CI: 2.907-15.808 ) as factors affecting frailty among middle-aged and elderly residents. Following age stratification, physical activity ( OR=0.817, 95%CI: 0.681-0.981 ) and sleep quality ( OR: 3.076-11.566, 95%CI: 2.518-18.216 ) as factors affecting frailty among subjects at ages of 45 to 59 years, while sleep quality ( OR: 3.777-11.827, 95%CI: 3.002-18.547 ) significantly correlated with frailty among residents at ages of 60 to 69 years. Conclusion Physical activity and sleep quality are associated with the risk of frailty among middle-aged and elderly populations.
|
|
Received: 30 August 2021
Revised: 31 December 2021
Published: 14 March 2022
|
|
|
|
|
|
[1] HOOGENDIJK E O,AFILALO J,ENSRUD K E,et al.Frailty:implications for clinical practice and public health[J].Lancet,2019,394(10206):1365-1375.
[2] 尹佳慧,曾雁冰,周鼒,等.中国老年人衰弱状况及其影响因素分析[J].中华流行病学杂志,2018,39(9):1244-1248.
YIN J H,ZENG Y B,ZHOU Z,et al.Study on the status of frailty and related determinants among the elderly in China[J].Chin J Epidemiol,2018,39(9):1244-1248.
[3] 阮晔,郭雁飞,孙双圆,等.上海市50岁及以上人群衰弱状况研究[J].中华疾病控制杂志,2019,23(4):445-451.
RUAN Y,GUO Y F,SUN S Y,et al.Evaluation of frailty in people aged 50 years and above in Shanghai[J].Chin J Dis Control Prev,2019,23(4):445-451.
[4] GOBBENS R J,UCHMANOWICZ I.Assessing frailty with the Tilburg Frailty Indicator(TFI):a review of reliability and validity[J].Clin Interv Aging,2021,16:863-875.
[5] 奚兴,郭桂芳,孙静.中文版Tilburg衰弱评估量表的信效度研究[J].护理学报,2013,20(16):1-5.
XI X,GUO G F,SUN J.Reliability and validity of Chinese version of Tilburg Frailty Indicator[J].J Nurs,2013,20(16):1-5.
[6] 路桃影,李艳,夏萍,等.匹兹堡睡眠质量指数的信度及效度分析[J].重庆医学,2014,43(3):260-263.
LU T Y,LI Y,XIA P,et al.Analysis on reliability and validity of the Pittsburgh Sleep Quality Index[J].Chongqing Med,2014,43(3):260-263.
[7] World Health Organization.Global Physical Activity Questionnaire(GPAQ)analysis guide[EB/OL].[2021-12-31].http://www.who.int/chp/steps/resources/GPAQ_Analysis_Guide.pdf.
[8] FAN J,LIU Y,WANG Q,et al.Association of insomnia and multidimensional frailty in community-dwelling older adults:a cross-sectional survey[J].J Clin Nurs,2021,31(1/2):167-173.
[9] 樊少仪,徐福平,裴中,等.广州地区老年人睡眠障碍与衰弱的相关性[J].实用医学杂志,2020,36(14):1908-1912.
FAN S Y,XU F P,PEI Z,et al.Relationship between frailty and sleep disturbances of the elderly in Guangzhou province[J].J Pract Med,2020,36(14):1908-1912.
[10] GARBARINO S,LANTERI P,DURANDO P,et al.Co-morbidity,mortality,quality of life and the healthcare/welfare/social costs of disordered sleep:a rapid review[J/OL].Int J Environ Res Public Health,2016,13(8)(2016-08-18)[2021-12-31].https://doi.org/10.3390/ijerph13080831.
[11] 张斯蒙,田沛茹,倪萍,等.脑出血患者不同出血部位与睡眠的相关性研究[J].预防医学,2019,31(4):346-350.
ZHANG S M,TIAN P R,NI P,et al.Association between bleeding sites and sleeping status in patients with cerebral hemorrhage[J].Prev Med,2019,31(4):346-350.
[12] ÁLVAREZ-SATTA M,BERNA-ERRO A,CARRASCO-GARCIA E,et al.Relevance of oxidative stress and inflammation in frailty based on human studies and mouse models[J].Aging(Albany NY),2020,12(10):9982-9999.
[13] ANGULO J,EL ASSAR M,ÁLVAREZ-BUSTOS A,et al.Physical activity and exercise:strategies to manage frailty[J/OL].Redox Biol,2020,35(2020-03-20)[2021-12-31].https://doi.org/10.1016/j.redox.2020.101513.
[14] TARAZONA-SANTABALBINA F J,GÓMEZ-CABRERA M C,PÉREZ-ROS P,et al.A multicomponent exercise intervention that reverses frailty and improves cognition,emotion,and social networking in the community-dwelling frail elderly:a randomized clinical trial[J].J Am Med Dir Assoc,2016,17(5):426-433.
[15] KYU H H,BACHMAN V F,ALEXANDER L T,et al.Physical activity and risk of breast cancer,colon cancer,diabetes,ischemic heart disease,and ischemic stroke events:systematic review and dose-response meta-analysis for the Global Burden of Disease Study2013[J/OL].BMJ,2016,354(2016-08-09)[2021-12-31].https://doi.org/10.1136/bmj.i3857.
[16] KOJIMA G,LILJAS A,ILIFFE S,et al.A systematic review and meta-analysis of prospective associations between alcohol consumption and incident frailty[J].Age Ageing,2018,47(1):26-34. |
|
|
|
