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| A study on the inducing factors of type 2 diabetic ketosis among type 2 diabetes mellitus patients |
| WANG Li-jun, SONG Ying-xiang, YE Xiao, ZHANG Wei, ZHAO Yu, MA Jiang-bo, XING Yu-bo, HUA Yan-yin
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Department of Endocrinology in Zhejiang Provincial People'
s Hospital, Hangzhou, Zhejiang, 310014,China |
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Abstract Objective To investigate the inducing factors of diabetic ketosis(DK) in type 2 diabetes mellitus(T2DM) patients for more effective prevention. Methods A total of 545 T2DM patients with DK who received treatment in Zhejiang Provincial Diabetes Prevention and Treatment Center from June 2011 to June 2015 were enrolled, which contains 297 newly-diagnosed ketosis-prone diabetic(KPD)patients (KPD group) and 248 T2DM patients with DK(T2DM group), the etiological factors and clinical characteristics were analyzed retrospectively. Results The leading causes of DK were long term nonintervetion(71.71%)and infection(15.15%)in KPD group,while unadjusted therapeutic regimen(39.91%)and break-off(22.98%)and infection(20.97%) were the leading cause in T2DM group. Compared with T2DM group, patients in KPD group were younger(P<0.01), and had lower BMI index(P<0.01), higher HbA1c level(P<0.01), more serious ketosis patients(urine ketone≥++, P<0.05) and more DKA patients(P<0.05).Conclusion T2DM patients with ketosis could not be ignored, especially the KPD patients.More attention should be paid to diabetes health education, and screening of high-risk group and long term follow-up in patients with T2DM are effective means to reduce the incidence of DK in T2DM.
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Received: 10 May 2016
Published: 21 November 2017
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