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| Association between chronic hepatitis B virus infection anddiabetes among adults |
| WANG Hao*, CHEN Lingli, XIE Kaixu, WANG Chunmei, CAO Yuan, SHEN Dun, ZHANG Xiaoyi, ZHU Shuiqing, HU Ruying, BIAN Zheng, GUO Yu, YU Min, CHEN Zhengming, LI Liming
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| * Department of Non-communicable Diseases Control and Prevention, Zhejiang Provincial Center for Diseases Control and Prevention, Zhejiang, Hangzhou 310051, China |
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Abstract Objective To explore the association between chronic hepatitis B virus infection and diabetes among adults. Methods The baseline data of China Kadoorie Biobank ( CKB ) study from Tongxiang of Zhejiang Province was used for analysis. Community residents were investigated in the study from August 2004 to May 2008, including questionnaire survey, physical measurement and biological sample test. Univariate and multivariate logistic regression models were used to estimate the association of chronic hepatitis B virus infection with diabetes. Results Totally 52 888 participants were included in the final analysis. The overall prevalence of HBsAg-positive was 3.55% ( N=1 877 ). The overall prevalence of diabetes was 5.17% ( N=2 733 ). The prevalence of HBsAg-positive in diabetic patients was 3.51% ( N=96 ). Both univariate and multivariate logistic regression models indicated that there was no association between chronic hepatitis B virus infection and diabetes（ P>0.05 ）. Conclusion No significant association has been found between chronic hepatitis B virus infection and diabetes among adults.
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Received: 27 July 2020
Revised: 28 September 2020
Published: 14 January 2021
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