|
|
Incidence and influencing factors for HIV infection among men who have sex with men in Hangzhou |
LI Xi-ting,LUO Yan,ZHANG Xing-liang,JIN Jie,XU Ke,LUO Wen-jie,LI Qing-chun
|
Department of HIV/AIDS and STDs Control and Prevention,Hangzhou Center for Disease Control and Prevention,Hangzhou,Zhejiang 310021,China |
|
|
Abstract Objective To study HIV incidence and related factors among men who have sex with men(MSM)in Hangzhou. Methods We conducted a prospective cohort study consisted of 523 HIV-negative MSM in Hangzhou.We collected their sociodemographic and behavior information by questionnaire and blood samples for HIV and syphilis detection at baseline and during follow-up period. HIV seroconversion was defined as the end point to calculate the HIV incidence. We analyzed the influencing factors for HIV infection among MSM by cox regression. Results We observed a total of 374 participants for 12 months,accounting for 71.51%. There were 16 HIV positive cases and the HIV incidence rate was 6.57/100 person-years. Multivariate cox regression analysis showed that less than 30 years old(HR=10.050,95%CI:2.576-39.212),living in Hangzhou for more than 2 years(HR=0.082,95%CI:0.020-0.341)and having unprotected anal intercourse with casual male partners in the past 3 months(HR=0.060,95%CI:0.019-0.188)were associated with HIV incidence. Conclusio HIV incidence among MSM in Hangzhou was relatively high. The MSM who were less than 30 years old,living in Hangzhou for less than 2 years and having unprotected anal intercourse with casual male partners have higher risk of HIV infection.
|
Published: 26 September 2018
|
|
|
|
|
[1] Ministry of Health. China 2010 UNGASS Country Progress Report[R/OL] .(2010-04-01)[2018-04-25] . http://data.unaids.org/ pub/Report/2010/china_ 2010_country_progress_report_en.pdf. [2] 中国疾病预防控制中心性病艾滋病预防控制中心性病控制中心. 2016年第3季度全国艾滋病性病疫情[J] . 中国艾滋病性病,2016,22(11):849. [3] 蔡于茂,宋亚娟,刘惠,等. 2011—2016年深圳市男男性行为人群梅毒和HIV感染情况及影响因素[J] . 中华预防医学杂志,2017,51(11):994-1000. [4] DONG Z,XU J,ZHANG H,et al. HIV incidence and risk factors in Chinese young men who have sex with men-a prospective cohort study[J] . PLoS One,2014,9(5):e97527. [5] LIU G W,LU H Y,WANG J,et al. Incidence of HIV and syphilis among men who have sex with men(MSM)in Beijing:an open cohort study[J] . PLoS ONE,2015,10(10):e0138232. [6] JIA Z,HUANG X,WU H,et al. HIV burden in men who have sex with men:a prospective cohort study 2007-2012[J] . Scientific Reports,2015,5(2):11205. [7] LI D,YANG X,ZHANG Z,et al. Incidence of co-infections of HIV,herpes simplex virus type 2 and syphilis in a large cohort of men who have sex with men in Beijing,China[J] . PLoS One,2016,11(1):e0147422. [8] 惠珊,李一,闫红梅,等. 哈尔滨市男男性行为人群HIV新发感染及失访影响因素分析[J] . 中华流行病学杂志,2015,36(12):1381-1383. [9] WANG Q Q,CHEN X S,YIN Y P,et al. HIV prevalence,incidence and risk behaviours among men who have sex with men in Yangzhou and Guangzhou,China:a cohort study[J] . Journal of the International AIDS Society,2014,17(4):18849. [10] PENG Z H,YANG H T,NORRIS J,et al. HIV incidence and predictors associated with retention in a cohort of men who have sex with men in Yangzhou,Jiangsu Province,China[J] . PLoS One,2012,7(12):e52731. [11] GAROFALO R,HOTTON A L,KUHNS L M,et al. Incidence of HIV infection and sexually transmitted infections and related risk factors among very young men who have sex with men[J] . Journal of Acquired Immune Deficiency Syndromes,2016,72(1):79-86. [12] THIENKRUA W,TODD C S,CHONWATTANA W,et al. Incidence of and temporal relationships between HIV,herpes simplex II virus,and syphilis among men who have sex with men in Bangkok,Thailand:an observational cohort[J] . BMC Infectious Diseases,2016,16(1):340. [13] MULHALL B P,WRIGHT S T,DE LA MATA N,et al. Risk factors associated with incident sexually transmitted infections in HIV-positive patients in the Australian HIV Observational Database:a prospective cohort study[J] . HIV Medicine,2016,17(8):623-630. [14] ZHANG J F,GUO Z,PAN X,et al. Highlighting the crucial role of Hangzhou in HIV-1 transmission among men who have sex with men in Zhejiang,China[J] . Scientific Reports,2017,7(1):13892. [15] LI D L,LI S M,LIU Y J,et al. HIV incidence among men who have sex with men in Beijing:a prospective cohort study[J] . BMJ Open,2012,2(6):e001829. [16] 陈胜林,吴文杰. 男男性行为人群HIV感染率及影响因素分析[J] . 浙江预防医学,2015,27(10):992-994. [17] 周娓,元国平,岑焕新. 男男性行为人群HIV抗体定期检测及其影响因素分析[J] . 浙江预防医学,2016,28(1):28-31. [18] 贺淑芳,李桂英,孙燕鸣,等.2010—2013年北京市男性流动人口艾滋病哨点监测结果分析[J] .中国艾滋病性病,2014, 20(9):668-671. [19] 谭文倩,赵俊仕,刘志胜,等.长沙市2012—2014年男男性接触人群HIV感染趋势分析[J] .实用预防医学,2015,22(8):912-914. [20] 魏巍,李立明,曹卫华,等. 北京市海淀区男男性接触者性行为特征及HIV感染影响因素[J] . 首都公共卫生,2015,9(5):198-202. |
|
|
|