|
|
Analysis on adverse events following immunization surveillance among children in Shushan |
JIANG Wei-wei,CUI Guang-hui,LI Yan-yan,SHI Zhao-hua,ZU Ping
|
The Center for Disease Control and Prevention of Shushan,Hefei,Anhui 230031,China |
|
|
Abstract Objective To analyze the occurrence features of adverse event following immunization(AEFI)among children in Shushan,and to evaluate the immunization safety related to vaccines,and the implementation of AEFI information management system.Methods AEFI cases and vaccination data of children in Shushan from 2014 to 2017 were collected by National AEFI Monitoring Information Management system and Vaccination Information system of Anhui Province. Descriptive epidemiological methods were used to analyze the incidence rate of AEFI,the characteristics of cases,the classification and the clinical manifestations.Results 386 cases were reported during 2014 to 2017. The reported incidence rate of AEFI was 30.85 per 100,000 doses,which showed a decreasing trend year by year (P<0.05). The reported incidence rate of AEFI in male and female was 31.54 per 100,000 doses and 30.07 per 100,000 doses,respectively. The reported incidence rate of AEFI between male and female showed no significant difference(P>0.05). The reported incidence rate of AEFI in children aged one to two(two was not included) scored the highest,which was 39.44 per 100,000 doses; the reported incidence rate of AEFI in children aged four to five(five was not included) scored the lowest,which was 4.91 per 100,000 doses. In the group one vaccines,the reported incidence rate of AEFI of Leprosy vaccine(65.12 per 100,000 doses),DT vaccine(53.76 per 100,000 doses) and AC meningitis conjugated vaccine(52.02 per 100,000 doses) ranked first,second and third. In the group two vaccines,the reported incidence rate of AEFI of 23-valent pneumonic polysaccharide vaccine (107.99 per 100,000 doses),DTaP-IPV/Hib combination vaccine(105.03 per 100,000 doses) and DTaP-Hib vaccine(51.42 per 100,000 doses) ranked first,second and third. The main reactions of AEFI were fever and redness. Vaccine reactions were often occurred within 1d after vaccination.Conclusions The AEFI monitoring system in Shushan is in good condition. The reported incidence rate of AEFI varies in age and vaccine varieties. Training and digitalizd construction of vaccination outpatient service should be strengthened in order to further improve the quality of vaccination service and AEFI monitoring.
|
Published: 25 July 2018
|
|
|
|
|
[1] 吴浩飞,孙亨凡,孟胜利,等. 简述疫苗安全性管理[J] . 微生物学免疫学进展,2013,41(5):69-74. [2] 叶家楷,李克莉,许涤沙,等. 中国2015年疑似预防接种异常反应监测分析[J] . 中国疫苗和免疫,2017,23(5):481- 492,511. [3] 陈敏,梁亚琼,徐鹭,等. 2013—2016年南京市疑似预防接种异常反应监测分析[J] . 现代预防医学,2017,44(23):4284- 4288. [4] 王富良,孙向珏,许二萍,等. 杭州市萧山区2010—2016年4起疑似预防接种异常反应死亡案例分析[J] . 中国疫苗和免疫,2017,23(5):593-594,600. [5] 张磊. 二类疫苗短缺的背后[N] . 健康报,2016-07-15(2). [6] 宋开发,王运超,黄继贵. 湖北省荆州市2012—2016年疑似预防接种异常反应监测分析[J] . 中国疫苗和免疫,2017,23(4):458-462. [7] 陈茂芳,吴爱兰. 东阳市疑似预防接种异常反应监测结果分析[J] . 预防医学,2017,29(6):607-609. [8] 庄菱,刘大卫,郭飚,等. 疑似预防接种异常反应个案报告影响因素分析[J] . 中国疫苗和免疫,2008,14(1):55-58. [9] 张驯,刘友全,凡娅,等. 2015—2016年绵阳市疑似预防接种异常反应监测结果[J] . 职业与健康,2017,33(18):2576- 2579. [10] 王涛,杨俊英,范肖肖,等. 2015—2016年北京市昌平区疑似预防接种异常反应监测分析[J] . 中国疫苗和免疫,2017,23(3):317-321. [11] 魏莉延,张宝丹,王伟. 浅释疑似预防接种不良反应发生原因及防范对策[J] . 中国医学创新,2012,9(32):157-158. [12] 常华,许彤. 浅析接种吸附无细胞百白破疫苗儿童出现副反应的原因及护理方法[J] . 当代医药论丛,2014(10):71-72. [13] 陈佳婧,应颖,蒋丽丽. 2009—2015年上海市普陀区疑似预防接种异常反应监测结果分析[J] . 现代预防医学,2017,44(1):174-176,180. [14] 顾晓明. 南通市通州区2014年疑似预防接种异常反应监测情况分析[J] . 中国初级卫生保健,2016,30(3):47-48. [15] 魏瑜梅,杜国明,陆明霞,等. 张家港市2012年疑似预防接种异常反应监测分析[J] . 江苏卫生保健,2014,16(6):8-9. [16] 束方燕,粱峰,潘燕,等. 2015—2016年江苏省江阴市疑似预防接种异常反应监测结果分析[J] . 医学动物防制,2018,34(2):190-193. [17] 高汝琼. 不同剂次百白破接种后不良反应流行病学特征及其预防措施[J] . 临床合理用药杂志,2017,10(33):33-34. |
|
|
|