Screening of Mycobacterium tuberculosis and HIV co-infection in Ningbo City
SANG Guoxin1, CHEN Tong1, CHE Yang1, CHEN Yunpeng2, HE Tianfeng1
1. Department of Tuberculosis Control and Prevention, Ningbo Center for Disease Control and Prevention, Ningbo, Zhejiang 315010, China; 2. School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, China
Abstract：Objective To analyze the screening results of Mycobacterium tuberculosis (MTB) and HIV co-infections in Ningbo City from 2012 to 2020, so as to provide insights into improving the tuberculosis control strategy. Methods Data pertaining to HIV antibody testing among tuberculosis patients, MTB testing among HIV/AIDS patients, treatment of patients with MTB and HIV co-infections and prognosis of anti-tuberculosis therapy were collected from the annual working reports for the management of MTB and HIV co-infections in Ningbo City from 2012 to 2020, and the screening, treatment and prognosis of MTB and HIV co-infections were analyzed. Results A total of 35 385 newly identified tuberculosis patients were reported in Ningbo City from 2012 to 2020, and there were 5 854 cases receiving HIV testing. The annual mean percentage of HIV screening was 17.57%, and the HIV screening rate appeared a tendency towards a rise in Ningbo City from 2012 to 2020 (χ2trend=4 926.309, P<0.001). Eleven patients were tested positive for HIV, with an annual mean HIV positive rate of 0.19%. A total of 26 043 HIV/AIDS patients received MTB screening, with an annual mean screening rate of 95.78%, and the annual screening rate of MTB appeared a tendency towards a rise in Ningbo City from 2012 to 2020 (χ2trend=79.077, P<0.001). A total of 81 tuberculosis patients were detected, with an annual mean detection rate of 0.31%. Among the 92 patients with MTB and HIV co-infections, there were 81 patients receiving anti-tuberculosis and antiviral therapy simultaneously (88.04%), 8 cases receiving anti-tuberculosis therapy alone (8.70%), 2 cases receiving antiviral therapy alone (2.17%) and 1 case without therapy (1.09%). Among the 89 MTB and HIV co-infected patients receiving anti-tuberculosis therapy, 27 cases were cured (30.34%), 53 cases completing the course of treatment (59.55%) and 7 cases died. Conclusions The MTB screening rate among HIV/AIDS patients and the percentage of MTB and HIV co-infected patients with successful anti-tuberculosis treatment were high in Ningbo City from 2012 to 2020; however, the HIV screening rate should be improved among tuberculosis patients.
桑国鑫, 陈同, 车洋, 陈云鹏, 贺天锋. 宁波市结核分枝杆菌和艾滋病病毒双重感染筛查结果[J]. 预防医学, 2022, 34(11): 1121-1124.
SANG Guoxin, CHEN Tong, CHE Yang, CHEN Yunpeng, HE Tianfeng. Screening of Mycobacterium tuberculosis and HIV co-infection in Ningbo City. Preventive Medicine, 2022, 34(11): 1121-1124.
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