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预防医学  2021, Vol. 33 Issue (12): 1220-1222    DOI: 10.19485/j.cnki.issn2096-5087.2021.12.006
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妊娠晚期贫血的影响因素研究
陈晓雯, 姜李媛, 陈亚, 郭利芳, 朱旭红
杭州市妇产科医院妇女保健部,浙江 杭州 310016
Influencing factors for anemia in the third trimester of pregnancy
CHEN Xiaowen, JIANG Liyuan, CHEN Ya, GUO Lifang, ZHU Xuhong
Department of Women's Health, Hangzhou Women's Hospital, Hangzhou, Zhejiang 310016, China
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摘要 目的 分析妊娠晚期贫血的影响因素,为预防妊娠晚期贫血提供依据。方法 选择2019年10—12月在杭州市妇产科医院足月分娩的产妇为调查对象,通过产科电子病历系统收集基本信息,分别于妊娠中期和晚期检测血清铁蛋白、维生素B12、叶酸和血红蛋白;采用多因素Logistic回归模型分析妊娠晚期贫血的影响因素。结果 纳入产妇1 143人,年龄MQR)为29(4)岁;孕前体重正常1 050人,占91.86%;经产267人,占23.36%。发生妊娠晚期贫血74例,发生率为6.92%。多因素Logistic回归分析结果显示,经产(OR=1.714,95%CI:1.032~2.848)、妊娠中期铁缺乏(OR=3.301,95%CI:1.401~7.781)、妊娠晚期铁缺乏(OR=14.134,95%CI:1.944~102.774)和妊娠晚期叶酸不足(OR=2.960,95%CI:1.295~6.766)与妊娠晚期贫血存在统计学关联。结论 妊娠晚期发生贫血与妊娠中期和晚期铁缺乏、妊娠晚期叶酸不足和经产有关。
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陈晓雯
姜李媛
陈亚
郭利芳
朱旭红
关键词 妊娠期贫血血清铁蛋白血清叶酸    
AbstractObjective To explore the influencing factors for maternal anemia during the third trimester of pregnancy, so as to provide the evidence for the effective prevention of anemia. Methods Data of parturients, who received prenatal care and delivered at Hangzhou Women's Hospital from October to December of 2019 were retrospectively collected and analyzed. The obstetric electronic medical record system of this hospital was used to collect general information of the subjects. Serum ferritin, serum vitamin B12, serum folic acid and hemoglobin were determined at the second and third trimester. A multivariate logistic regression model was used to analyze the influencing factors for anemia in the third trimester. Results A total of 1 143 parturients were enrolled, with a median age of 29 ( interquartile range: 4 ) years. Among them, 1 050 cases had normal weight before pregnancy, accounting for 91.86%; 267 cases were multiparas, accounting for 23.36%; 74 cases of anemia occurred during the third trimester of pregnancy, accounting for 6.92%.Multivariate logistic regression analysis indicated that the multipara(OR=1.714,95%CI: 1.032-2.848), iron deficiency duiring the second trimester(OR=3.301,95%CI: 1.401-7.781), iron deficiency during the third trimester (OR=14.134,95%CI: 1.944-102.774)and folate deficiency during the third trimester(OR=2.960,95%CI: 1.295-6.766)were influencing factors for anemia during the third trimester. Conclusion Anemia during the third trimester of pregnancy is related to iron deficiency during the second and third trimesters, folic acid deficiency during the third trimester, and multipara.
Key wordspregnancy    anemia    serum ferritin    serum folic acid
收稿日期: 2021-07-19      出版日期: 2021-12-03
ZTFLH:  R714.14  
基金资助:杭州市卫生科技计划项目(0020190040)
通信作者: 朱旭红,E-mail:1023990898@qq.com   
作者简介: 陈晓雯,硕士,主治医师,主要从事妇女保健工作
引用本文:   
陈晓雯, 姜李媛, 陈亚, 郭利芳, 朱旭红. 妊娠晚期贫血的影响因素研究[J]. 预防医学, 2021, 33(12): 1220-1222.
CHEN Xiaowen, JIANG Liyuan, CHEN Ya, GUO Lifang, ZHU Xuhong. Influencing factors for anemia in the third trimester of pregnancy. Preventive Medicine, 2021, 33(12): 1220-1222.
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http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2021.12.006      或      http://www.zjyfyxzz.com/CN/Y2021/V33/I12/1220
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