Abstract：Objective To explore the association of hypertriglyceridemic waist phenotype ( HTGW ) with impaired fasting glucose ( IFG ) and diabetes, so as to provide reference for the early prevention and control of diabetes. Methods The survey was conducted among 35 to 75-year-old residents in 8 project sites in Jiangsu Province from 2015 to 2019. The information about demography and lifestyle was collected by the general information questionnaire and the primary screening questionnaire from the National Center for Cardiovascular Diseases; waist circumference, height, weight, triglyceride, high-density lipoprotein cholesterol, total cholesterol and fasting plasma glucose were measured. The multinomial logistic regression model was employed to analyze the association of HTGW with IFG and diabetes. Results A total of 118 383 subjects were included, among whom 21 851 cases of HTGW, 27 245 cases of IFG and 22 899 cases of diabetes were identified, with the prevalence of 18.46%, 23.01% and 19.34%. The multinomial logistic regression analysis showed HTGW was statistically associated with IFG ( OR=1.414, 95%CI: 1.343-1.489 ) and diabetes ( OR=2.216, 95%CI: 2.098-2.341 ). Conclusion HTGW is associated with IFG and diabetes, which make it possible to be an indicator for screening and assessment of glucose abnormality in middle-aged and elderly population.
丁有红, 崔岚, 苏健, 陈路路, 陶然, 覃玉. 中老年人群高三酰甘油腰围表型与空腹血糖受损、糖尿病的关系研究[J]. 预防医学, 2021, 33(2): 125-129.
DING Youhong, CUI Lan, SU Jian, CHEN Lulu, TAO Ran, QIN Yu. Association of hypertriglyceridemic waist phenotype with impaired fasting glucose and diabetes in middle-aged and elderly population. Preventive Medicine, 2021, 33(2): 125-129.
[1] 中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2017年版)[J]. 中华糖尿病杂志,2018,10(1):4-67. [2] CHO N H,SHAW J E,KARURANGA S,et al.IDF diabetes atlas:global estimates of diabetes prevalence for 2017 and projections for 2045[J]. Diabetes Res Clin Pract,2018,138(4):271-281. [3] 柳怡莹,程筱玲,邓偲婕,等. 女性2型糖尿病患者高三酰甘油腰围表型与甲状腺激素的相关性研究[J]. 中国全科医学,2020,23(33):4172-4177,4182. [4] 何向阳,刘峥,徐英,等. 肥胖与四种常见慢性病的相关性分析[J]. 预防医学,2020,32(7):692-697. [5] 宋文娟,吴俊杰,李玉涛,等. 2型糖尿病患者肥胖与内分泌指数的关系研究[J]. 预防医学,2020,32(5):508-511. [6] 张文,解为慈,刘文. 高甘油三酯腰围表型与糖尿病发病关系的Meta分析[J]. 海南医学,2016,27(3):490-494. [7] MA C M,LIU X L,LU N,et al.Hypertriglyceridemic waist phenotype and abnormal glucose metabolism:a system review and meta-analysis[J]. Endocrine,2019,64(3):469-485. [8] LU J,XUAN S,DOWNING N S,et al.Protocol for the China PEACE(Patient-centered Evaluative Assessment of Cardiac Events)million persons project pilot[J]. BMJ Open,2016,6(1):e010200. [9] 邓偲婕,万沁,程筱玲. 高三酰甘油腰围表型与糖尿病前期及2型糖尿病发病风险的关系[J]. 天津医药,2019,47(8):824-828. [10] 吴洵,覃玉,苏健,等. 江苏省35~75岁居民血脂异常患病和治疗情况及影响因素分析[J]. 中国慢性病预防与控制,2020,28(4):291-295. [11] ZHAO K,YANG S S,WANG H B,et al.Association between the hypertriglyceridemic waist phenotype and prediabetes in Chinese adults aged 40 years and older[J].J Diabetes Res,2018,2018:1-9. [12] 李宝新,郭淑芹,姚琪,等. 社区中老年人群糖调节受损调查[J]. 预防医学,2019,306(2):62-66. [13] CAI L,LI X,CUI W,et al.Trends in diabetes and pre-diabetes prevalence and diabetes awareness,treatment and control across socioeconomic gradients in rural southwest China[J]. J Public Health,2018,40(2):375-380. [14] WANG L,GAO P,ZHANG M,et al.Prevalence and ethnic pattern of diabetes and prediabetes in China in 2013[J]. JAMA,2017,317(24):2515-2523. [15] 马春明,刘晓丽,高国芹,等. 青少年高甘油三酯血症-腰围表型与心血管危险因素聚集相关[J]. 中华内分泌代谢杂志,2015,31(2):95-98. [16] 申志祥,顾寒寒,郑卉,等. 2017年南京社区老年人群高甘油三酯-腰围表型相关影响因素与心血管危险因素聚集关系分析[J]. 实用老年医学,2019,33(1):44-48. [17] 王晓红,祝爽爽,刘爱群,等. 高三酰甘油血症-腰围表型临床特征及其与糖尿病前期和糖尿病的关系研究[J]. 中国全科医学,2019,22(19):2340-2344. [18] CHEN S,GUO X,YU S,et al.Association between the hypertriglyceridemic waist phenotype,prediabetes,and diabetes mellitus in rural Chinese population:a cross-sectional study[J]. Int J Environ Res Public Health,2016,13(4):368. [19] OLIVEIRA C C D,RORIZ A K C,EICKEMBERG M,et al. Hypertriglyceridemic waist phenotype:association with metabolic disorders and visceral fat in adults[J]. Nutr Hosp,2014,30(1):25-31.
