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预防医学  2017, Vol. 29 Issue (11): 1123-1126    DOI: 10.19485/j.cnki.issn1007-0931.2017.11.010
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副溶血性弧菌散发感染危险因素的病例对照研究
林云, 孙炀明, 罗建勇, 王恒辉
嘉兴市疾病预防控制中心,浙江 嘉兴 314050
A case-control study on risk factors of vibrio parahaemolyticus sporadic infection
LIN Yun, SUN Yang-ming, LUO Jian-yong, WANG Heng-hui
The Center for Disease Control and Prevention of Jiaxing City,Jiaxing,Zhejiang,314050,China
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摘要 目的 了解嘉兴市副溶血性弧菌散发感染的危险因素,为预防和控制食源性疾病提供依据。方法 采用病例对照研究方法,于2013—2016年检索食源性疾病监测报告系统,将全市哨点医院根据 WS 271—2007《感染性腹泻诊断标准》实验室确诊的副溶血性弧菌散发病例纳入病例组;与病例居住同一社区、相同性别、同一年龄段的正常人群按1∶1纳入对照组。采用问卷调查方法收集研究对象基本资料和可疑危险因素。结果 调查副溶血性弧菌散发病例211例,正常对照211人,病例组与对照组在文化程度及职业分布上差异均无统计学意义(P>0.05)。79.62%的病例发病时间集中在7—10月。病例的临床症状主要表现为腹泻(100.00%)、腹绞痛(86.73%)、恶心(56.40%)和呕吐(51.66%)。多因素条件Logistic回归分析结果显示,发病前5 d内在外就餐史(OR=2.11,95%CI:1.15~3.86)、食用海水鱼(OR=2.72,95%CI:1.01~7.37)和海水虾(OR=4.42,95%CI:1.22~15.97)是感染副溶血性弧菌的独立危险因素。结论 嘉兴市居民副溶血性弧菌散发感染的主要危险因素是发病前5 d内在外就餐史以及食用海水鱼和海水虾。需针对危险因素,加强食品安全风险监管,提高居民食品安全意识,以降低副溶血弧菌感染的发生。
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林云
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关键词 副溶血性弧菌散发感染危险因素病例对照研究    
AbstractObjective To understand the risk factors of vibrio parahaemolyticus sporadic infection in Jiaxing,and to provide evidence to prevent and control foodborne diseases. Methods Case-control study was used and the food borne disease surveillance system was retrieved from 2013 to 2016. Based on the diagnostic criteria for infectious diarrhea (WS 271—2007),laboratory confirmed vibrio parahaemolyticus sporadic cases in Jiaxing City were enrolled into the case group. According to the ratio of 1∶1,the healthy population matched by identical community,gender and age was enrolled into control group. Questionnaire survey was used to collect the general information and risk factors of participants. The risk factors were analyzed by conditional multivariate logistic regression. Results A total of 211 vibrio parahaemolyticus sporadic cases and 211 healthy persons were investigated. There were no statistically significant difference about educational level,and the occupational distribution between case group and control group(P>0.05). The onset time of 79.62% cases was primarily from July to October,and the clinical symptoms were mainly diarrhea(100.00%),abdominal pain (86.73%),nausea (56.40%),and vomit (51.66%). Conditional logistic regression analysis showed that eating out 5 days prior to onset (OR=2.11,95%CI:1.15-3.86),eating marine fish (OR=2.72,95%CI:1.01-7.37) and marine shrimps (OR=4.42,95%CI:1.22-15.97) were the independent risk factors. Conclusion The major risk factors of vibrio parahaemolyticus sporadic infection of residents in Jiaxing were eating out 5 days prior to onset,eating marine fish and eating marine shrimps. Food safety supervision and resident awareness of food safety should be strengthened to lower the incidence risk of foodborne diseases such as vibrio parahaemolyticus infection.
Key wordsVibrio Parahaemolyticus    Sporadic infection    Risk factors    Case-control study
收稿日期: 2017-05-08      修回日期: 2017-08-26     
中图分类号:  R155  
通信作者: 林云,E-mail:ly_zyh@163.com   
作者简介: 林云,本科,主任医师,主要从事营养与食品卫生工作
引用本文:   
林云, 孙炀明, 罗建勇, 王恒辉. 副溶血性弧菌散发感染危险因素的病例对照研究[J]. 预防医学, 2017, 29(11): 1123-1126.
LIN Yun, SUN Yang-ming, LUO Jian-yong, WANG Heng-hui. A case-control study on risk factors of vibrio parahaemolyticus sporadic infection. Preventive Medicine, 2017, 29(11): 1123-1126.
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http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn1007-0931.2017.11.010      或      http://www.zjyfyxzz.com/CN/Y2017/V29/I11/1123
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