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预防医学  2018, Vol. 30 Issue (9): 889-892    DOI: 10.19485/j.cnki.issn2096-5087.2018.09.006
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陕西省HIV/AIDS 合并感染HBV病例分析
张超,付钰淋,任强,李华,邹扬帆,张梦妍,常文辉
陕西省疾病预防控制中心艾滋病预防控制所,陕西 西安 710054
Analysis of HIV/AIDS patients co-infected with HBV in Shaanxi Province
ZHANG Chao,FU Yu-lin,REN Qiang,LI Hua,ZOU Yang-fan,ZHANG Meng-yan,CHANG Wen-hui
Department of AIDS Prevention and Control,Shaanxi Provincial Center for Disease Control and Prevention,Xi'an,Shaanxi 710054,China
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摘要 目的 了解陕西省艾滋病病毒感染者和艾滋病患者(HIV/AIDS)合并感染乙型肝炎病毒(HBV)情况。方法 对陕西省2011年6月—2016年6月确证的1 018例HIV/AIDS病例进行乙肝五项检测(HBsAg、HBsAb、HBeAg、HBeAb和HBcAb),对HIV/AIDS病例的HBV感染情况进行描述性分析。结果 1 018例HIV/AIDS病例中,HBsAg阳性112例,阳性率为11.00%。共发现19种血清模式,HBsAb单阳最多,446例,占43.81%;五项全阴307例,占30.16%;“大三阳”16例,占1.57%;“小三阳”30例,占2.95%。彝族HIV/AIDS病例HBsAg阳性率和“大三阳”率分别为18.31%和5.63%,均高于汉族和其他少数民族的10.45%和1.27%(P<0.05)。结论 陕西省HIV/AIDS病例合并HBV感染率高于普通人群,彝族高于汉族和其他少数民族。
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张超,付钰淋,任强,李华,邹扬帆,张梦妍,常文辉
关键词 艾滋病艾滋病病毒乙型肝炎病毒合并感染    
AbstractObjective To investigate the status of HIV/AIDS patients co-infected with HBV and to provide scientific evidence for HBV prevention and control among HIV/AIDS patients in Shaanxi Province. Methods Totally 1 018 blood specimens were collected from HIV infected patients diagnosed by Shaanxi Provincial Center for Disease Control and Prevention from June 2011 to June 2016. The five HBV markers(HBsAg,HBsAb,HBeAg,HBeAb,HBcAb)for HIV/AIDS patients were tested,and a descriptive analysis was conducted for the Hepatitis B infection status of HIV/AIDS patients. Results Of 1 018 HIV/AIDS patients,112 patients(11.00%)were HBsAg positive. A total of 19 kinds of HBV marker's phenotype distribution were found. Of which,the inoculated population(HBsAg-,HBsAb+,HBeAb-,HBeAb-,HBcAb-)were 446 cases(43.81%),followed by the susceptible population(HBsAg-,HBsAb-,HBeAb-,HBeAb-,HBcAb-)which were 307 cases(30.16%) . The great three positive(HBsAg+,HBsAb-,HBeAg+,HBeAb-,HBcAb+)were 16 cases(1.57%)and the small three positive(HBsAg+,HBsAb-,HBeAg-,HBeAb+,HBcAb+)were 30 cases(2.95%) . The rate of HBsAg positive(18.31%)and great three positive(HBsAg+,HBsAb-,HBeAg+,HBeAb-,HBcAb+) (5.63%)in the Yi nationality were higher than that in the Han nationality and others(10.45%,1.27%) (P<0.05). Conclusion The rate of HIV/AIDS patients co-infected with HBV in Shaanxi Province was higher than that in the general population,and the rate for the Yi nationality was higher than that in the Han nationality and others.
Key wordsAIDS    HIV    Hepatitis B virus    Co-infection
     出版日期: 2018-09-04
ZTFLH:  R512.91  
  R512.62  
基金资助:陕西省疾病预防控制重大课题(2014A5)
通信作者: 常文辉,E-mail:changwenhui3@aliyun.com   
作者简介: 张超,硕士,检验师,主要从事艾滋病预防控制工作
引用本文:   
张超,付钰淋,任强,李华,邹扬帆,张梦妍,常文辉. 陕西省HIV/AIDS 合并感染HBV病例分析[J]. 预防医学, 2018, 30(9): 889-892.
ZHANG Chao,FU Yu-lin,REN Qiang,LI Hua,ZOU Yang-fan,ZHANG Meng-yan,CHANG Wen-hui. Analysis of HIV/AIDS patients co-infected with HBV in Shaanxi Province. Preventive Medicine, 2018, 30(9): 889-892.
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