Influencing factors for the willingness to receive pneumococcal vaccine among middle-aged and elderly population in Zhejiang Province
XU Yanping1, YAN Xiaotong2, YAO Dingming2, XU Yue2, ZHANG Xuehai2, SUN Jie3, XU Jinhang2
1. Longyou County Center for Disease Control and Prevention (Longyou County Institute of Public Health Supervision), Longyou, Zhejiang 324400, China; 2. Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051, China; 3. Quzhou Center for Disease Control and Prevention (Quzhou Institute of Public Health Supervision), Quzhou, Zhejiang 324000, China
Abstract：Objective To investigate the willingness to receive the pneumococcal vaccine and its influencing factors among middle-aged and elderly population in Zhejiang Province, so as to provide a basis for increasing the vaccination rate of pueumococcal among middle-aged and elderly population. Methods From March to May 2024, a multi-stage random sampling method was employed to recruit residents aged ≥50 years from 35 counties (cities or districts) in Zhejiang Province. Data on basic information, knowledge of pneumonia, pneumococcal vaccine, and willingness to receive pneumococcal vaccine were collected through questionnaire surveys. A multivariable logistic regression model was used to analyze influencing factors for the willingness to receive pneumococcal vaccine among middle-aged and elderly population. Results A total of 10 500 middle-aged and elderly population were surveyed. Among them, there were 5 202 males, accounting for 49.54%, and 5 298 females, accounting for 50.46%. The mean age was (65.11±9.05) years. Of the participants, 7 732 individuals were aware of pneumonia, accounting for 73.64%. A total of 1 724 individuals had received pneumococcal vaccine, corresponding to a vaccination rate of 16.42%. Furthermore, 5 138 participants expressed willingness to receive pneumococcal vaccine, with a willingness rate of 48.93%. The multivariable logistic regression analysis showed that middle-aged and elderly population aged ≥60 years (60-<70 years, OR=1.577, 95%CI: 1.433-1.736; ≥70 years, OR=2.110, 95%CI: 1.918-2.321), those with a history of chronic diseases (OR=1.250, 95%CI: 1.154-1.353), those who were recommended to receive the pneumonia vaccine by doctors (OR=4.896, 95%CI: 4.507-5.318), those who were aware of pneumonia (OR=1.460, 95%CI: 1.338-1.594), those who were aware that the elderly are prone to pneumonia (OR=1.490, 95%CI: 1.375-1.614), those who were aware of the causes of pneumonia (OR=1.559, 95%CI: 1.434-1.694), those who were aware that vaccination can prevent pneumonia (OR=2.196, 95%CI: 2.031-2.375), and those who were aware of the immunization schedule for pneumonia vaccine (OR=1.897, 95%CI: 1.683-2.124) had a higher willingness to receive pneumonia vaccine. Conclusions The willingness of middle-aged and elderly population in Zhejiang Province to receive pneumonia vaccine is related to age, history of chronic diseases, awareness of pneumonia, and awareness of pneumonia vaccine. It is recommended to strengthen health education on pneumonia and pneumonia vaccine for middle-aged and elderly population, in order to increase the willingness to receive the vaccine and vaccination rate.
徐艳平, 闫晓彤, 姚丁铭, 徐越, 张雪海, 孙洁, 徐锦杭. 浙江省中老年人肺炎疫苗接种意愿的影响因素研究[J]. 预防医学, 2025, 37(9): 881-885.
XU Yanping, YAN Xiaotong, YAO Dingming, XU Yue, ZHANG Xuehai, SUN Jie, XU Jinhang. Influencing factors for the willingness to receive pneumococcal vaccine among middle-aged and elderly population in Zhejiang Province. Preventive Medicine, 2025, 37(9): 881-885.
[1] KONG Z X,XIONG J,CHEN L,et al.The global, regional,national burden of lower respiratory infections caused by streptococcus pneumoniae between1990 and 2021[J/OL].Healthcare,2025[2025-08-21].https://doi.org/10.3390/healthcare13161982. [2] 中华预防医学会,中华预防医学会疫苗与免疫分会.肺炎球菌性疾病免疫预防专家共识(2020版)[J].中国疫苗和免疫,2021,27(1):1-47. Chinese Preventive Medicine Association,Vaccine,Immunology Branch of the Chinese Preventive Medicine Association.Expert consensus on immunoprophylaxis of pneumococcal disease(2020 version)[J].Chin J Vaccines Immunization,2021,27(1):1-47.(in Chinese) [3] 王圆媛,李靖欣,曹嘉倩,等.肺炎球菌结合疫苗免疫学替代终点的研究进展[J].中华预防医学杂志,2019,53(8):851-854. WANG Y Y,LI J X,CAO J Q,et al.Research progress of the surrogate of protection of pneumococcal conjugate vaccine[J].Chin J Prev Med,2019,53(8):851-854.(in Chinese) [4] 李文桂,陈雅棠.肺炎链球菌的免疫预防现状[J].中国病原生物学杂志,2025,20(5):677-682. LI W G,CHEN Y T.The status in the research of immunoprophylaxis of Streptococcus pneumoniae[J].J Pathog Biol,2025,20(5):677-682.(in Chinese) [5] 许玉洋,刘艳,安志杰.老年肺炎球菌多糖疫苗免疫反应和保护效果研究进展[J].中国公共卫生,2021,37(4):584-588. XU Y Y,LIU Y,AN Z J.Immune and protective effect of pneumococcal polysaccharide vaccine in elderly population:a review[J].Chin J Public Health,2021,37(4):584-588.(in Chinese) [6] 老年慢性呼吸系统疾病人群流感疫苗和肺炎球菌疫苗预防接种专家共识意见专家委员会,中华医学会老年医学分会呼吸病学组.老年慢性呼吸系统疾病人群流感疫苗和肺炎球菌疫苗接种专家共识(2024)[J].中华老年医学杂志,2024,43(10):1223-1235. Expert Committee of Consensus Opinion on Influenza Vaccine and Pneumococcal Vaccine Vaccination for Elderly People with Chronic Respiratory Diseases,Respiratory Group of Chinese Geriatrics Society.Expert consensus on influenza vaccine and pneumococcal vaccination in elderly people with chronic respiratory diseases(2024)[J].Chin J Geriatr,2024,43(10):1223-1235.(in Chinese) [7] 朱琳,高静,柏丁兮,等.中国居民肺炎球菌疫苗接种意愿的Meta分析[J].预防医学,2021,33(9):935-939,943. ZHU L,GAO J,BAI D X,et al.A meta-analysis of the vaccination willingness of pneumococcal vaccines in Chinese residents[J].China Prev Med J,2021,33(9):935-939,943.(in Chinese) [8] 刘紫欣,王慎玉,闫晓彤,等.2022年浙江省≥50岁居民流感和肺炎球菌疫苗接种情况及其影响因素分析[J].中国公共卫生,2024,40(1):44-49. LIU Z X,WANG S Y,YAN X T,et al.Coverage and influencing factors of influenza and pneumococcal vaccination among urban and rural residents 50 years old and over in Zhejiang Province,2022-a cross-sectional survey[J].Chin J Public Health,2024,40(1):44-49.(in Chinese) [9] 路明霞,李致远,牛乾,等.2020—2023年河南省50岁及以上人群3种非免疫规划疫苗接种现状分析[J].现代疾病预防控制,2025,36(1):19-23. LU M X,LI Z Y,NIU Q,et al.Analysis of non-immunization program vaccine coverage among people aged 50 years and older in Henan Province from 2020 to 2023[J].Mod Dis Control Prev,2025,36(1):19-23.(in Chinese) [10] 潘黎,钟培松,费洁.上海市嘉定区老年人肺炎疫苗接种意愿及影响因素调查[J].健康教育与健康促进,2017,12(4):343-345. PAN L,ZHONG P S,FEI J.Investigation of the pneumonia vaccination willingness and influencing factors among the elderly in Jiading District of Shanghai[J].Health Educ Health Promot,2017,12(4):343-345.(in Chinese) [11] 李依窈,李小菊,申小颖,等.老年人接种流行性感冒疫苗的影响因素分析[J].预防医学,2025,37(1):31-35. LI Y Y,LI X J,SHEN X Y,et al.Influencing factors for influenza vaccination among the elderly[J].China Prev Med J,2025,37(1):31-35.(in Chinese) [12] 谢小红. 三明市沙县区≥60岁人群23价肺炎球菌多糖疫苗接种意愿及影响因素调查[J].中国初级卫生保健,2024,38(8):91-94. XIE X H.Investigation on the intention and influencing factors of 23-valent pneumococcal polysaccharide vaccine among ≥60 years old in Shaxian district of Sanming[J].Chin Prim Health Care,2024,38(8):91-94.(in Chinese) [13] 朱琳,高静,柏丁兮,等.中国老年人肺炎球菌疫苗接种意愿影响因素的Meta分析[J].中华疾病控制杂志,2022,26(1):91-98. ZHU L,GAO J,BAI D X,et al.The influencing factors of vaccination willingness in pneumococcal vaccine in Chinese senior citizen:a Meta-analysis[J].Chin J Dis Control Prev,2022,26(1):91-98.(in Chinese) [14] 陆佳,陆昕悦,沈钰涛,等.上海市闵行区50岁以上人群流感、肺炎、带状疱疹疫苗接种意愿及其相关因素分析[J].中华预防医学杂志,2022,56(2):125-131. LU J,LU X Y,SHEN Y T,et al.Analysis on vaccination willingness and related factors of influenza,pneumonia,and herpes zoster vaccine among people over 50 years old in Minhang Ddistrict of Shanghai[J].Chin J Prev Med,2022,56(2):125-131.(in Chinese) [15] 叶露梦,郑广勇.象山县养老机构老年人健康素养调查[J].预防医学,2025,37(6):627-631. YE L M,ZHENG G Y.Health literacy among the elderly in nursing homes in Xiangshan County[J].China Prev Med J,2025,37(6):627-631.(in Chinese) [16] 王雯,张春焕,张周斌,等.广州市老年人23价肺炎球菌多糖疫苗接种意愿及影响因素分析[J].中国预防医学杂志,2024,25(3):372-378. WANG W,ZHANG C H,ZHANG Z B,et al.Analysis on willingness to receive 23-valent pneumococcal polysaccharide vaccine and its influencing factors among the elderly in Guangzhou[J].Chin Prev Med,2024,25(3):372-378.(in Chinese)
