Awareness of non-occupational post-exposure prophylaxis for AIDS among men who have sex with men in Yangzhou City
JIANG Yan1, LI Jincheng1, XU Chun1, YANG Kejiao1, YANG Wenbin1, XU Sheng2
1. Yangzhou Center for Disease Control and Prevention, Yangzhou, Jiangsu 225000, China; 2. Binhai County Center for Disease Control and Prevention, Binhai, Jiangsu 224500, China
Abstract：Objective To investigate the awareness rate of non-occupational post-exposure prophylaxis (nPEP) for AIDS and its influencing factors among men who have sex with men (MSM) in Yangzhou City, Jiangsu Province. Methods From January to June 2024, MSM aged ≥16 years in Yangzhou City were recruited using the snowball sampling method. Basic information, sexual behavior characteristics, awareness and usage of nPEP, and awareness of pre-exposure prophylaxis (PrEP) for AIDS were collected through questionnaire surveys. Factors affecting awareness of nPEP among MSM were analyzed using multivariable logistic regression model. Results A total of 740 participants were enrolled, with a median age of 29 (interquartile range, 14) years. There were 497 participants with a college degree and above educational level, accounting for 67.16%. A total of 541 participants resided in urban areas, accounting for 73.11%. The awareness rate of nPEP was 57.30%. The primary channels for awareness were the internet and healthcare institution promotions, with 159 and 119 participants, accounting for 37.50% and 28.07%, respectively. A total of 57 participants had utilized nPEP, with a usage rate of 7.70%. The main reason for using nPEP was having unprotected sex, with 21 participants, accounting for 36.84%. Multivariable logistic regression analysis revealed that unmarried MSM (OR=2.369, 95%CI: 1.236-4.540) and those who were aware of PrEP (OR=28.067, 95%CI: 17.664-44.597) had a significantly higher likelihood of being aware of nPEP. Conclusions The awareness rate and usage rate of nPEP among MSM in Yangzhou City are both relatively low. Awareness of nPEP is mainly influenced by marital status and whether participants are aware of PrEP.
姜艳, 李锦成, 许纯, 杨科佼, 杨文彬, 徐胜. 扬州市MSM人群艾滋病非职业暴露后预防知晓率调查[J]. 预防医学, 2025, 37(9): 903-906,912.
JIANG Yan, LI Jincheng, XU Chun, YANG Kejiao, YANG Wenbin, XU Sheng. Awareness of non-occupational post-exposure prophylaxis for AIDS among men who have sex with men in Yangzhou City. Preventive Medicine, 2025, 37(9): 903-906,912.
[1] 徐杰,张广,董薇.我国艾滋病病毒暴露前后预防措施的推广应用[J].中国艾滋病性病,2023,29(11):1167-1171. XU J,ZHANG G,DONG W.Popularization and application of preventive measures before and after HIV exposure in China[J].Chin J AIDS STD,2023,29(11):1167-1171.(in Chinese) [2] 何佳晋,居豪,吴超.中国MSM人群HIV新发感染率及其影响因素的Meta分析[J].预防医学,2022,34(1):70-77. HE J J,JU H,WU C.Incidence of new HIV infection and its influencing factors among men who have sex with men in China:a meta-analysis[J].China Prev Med J,2022,34(1):70-77.(in Chinese) [3] JIN J Y,SUN R S,MU T T,et al.Awareness and use of post-exposure prophylaxis for HIV prevention among men who have sex with men:a systematic review and meta-analysis[J/OL].Front Med(Lausanne),2022[2025-08-13].https://doi.org/10.3389/fmed.2021.783626. [4] 金屡华,唐慧玲,王凤英,等.浙江省金华市男男性行为人群HIV非职业暴露后预防使用意愿及影响因素[J].实用预防医学,2025,32(2):133-137. JIN L H,TANG H L,WANG F Y,et al.Willingness to use nonoccupational postexposure prophylaxis for HIV and its influencing factors among men who have sex with men in Jinhua City,Zhejiang Province[J].Pract Prev Med,2025,32(2):133-137.(in Chinese) [5] 张倩,罗德威,周乐,等.扬州市居民艾滋病非职业暴露后预防知晓情况调查[J].预防医学,2023,35(12):1093-1096. ZHANG Q,LUO D W,ZHOU L,et al.Awareness of HIV non-occupational post-exposure prophylaxis among residents in Yangzhou City[J].China Prev Med J,2023,35(12):1093-1096.(in Chinese) [6] 孙武,蔡卫平,李凌华.我国男男性行为人群HIV非职业暴露后预防的研究进展[J].中国热带医学,2023,23(3):314-318. SUN W,CAI W P,LI L H.Research progress in HIV non-occupational post-exposure prophylaxis among men who have sex with men in China[J].China Trop Med,2023,23(3):314-318.(in Chinese) [7] 江苏省政府艾滋病防治工作委员会办公室.2024年全省艾滋病防治工作进展[EB/OL].[2025-08-13].http://wjw.jiangsu.gov.cn/art/2022/11/30/art_7312_10693312.html. [8] 刘思辰,于飞,薛珲,等.七城市男男性行为者HIV暴露前后预防用药知晓和使用影响因素[J].中国艾滋病性病,2022,28(7):810-815. LIU S C,YU F,XUE H,et al.Awareness and utilization of HIV pre-exposure prophylaxis(PrEP)and post-exposure prophylaxis(PEP)among MSM in seven cities of China[J].Chin J AIDS STD,2022,28(7):810-815.(in Chinese) [9] 郑亦慧,谢言,魏巍.上海市男男性行为者艾滋病非职业暴露后预防的接受意愿和使用情况[J].上海预防医学,2022,34(2):134-138. ZHENG Y H,XIE Y,WEI W.Willingness to use and uptake of non-occupational post-exposure prophylaxis(nPEP)among men who have sex with men(MSM)in Shanghai[J].Shanghai J Prev Med,2022,34(2):134-138.(in Chinese) [10] 韩晶,李杰,王克荣,等.2019年我国三城市青年学生男男性行为人群HIV非职业暴露后预防用药的知识知晓和服务接受情况及相关因素[J].中华预防医学杂志,2020,54(11):1220-1226. HAN J,LI J,WANG K R,et al.Status and influencing factors of knowledge awareness and service acceptance of HIV non-occupational post-exposure prophylaxis of men who have sex with men among college students among three cities of China,2019[J].Chin J Prev Med,2020,54(11):1220-1226.(in Chinese) [11] 吴雨霏. 广西南宁、柳州市MSM人群艾滋病非职业暴露后预防的实施效果评价[D].南宁:广西医科大学,2023. WU Y F.Implementation evaluation of HIV non-occupational post-exposure prophylaxis among men who have sex with men in Nanning and Liuzhou,Guangxi.[D].Nanning:Guangxi Medical University,2023.(in Chinese) [12] 常恬悦,王丽娟,宋亮,等.男男性行为人群无保护肛交行为的影响因素分析[J].预防医学,2025,37(3):233-237,242. CHANG T Y,WANG L J,SONG L,et al.Influencing factors for unprotected anal intercourse among men who have sex with men[J].China Prev Med J,2025,37(3):233-237,242.(in Chinese) [13] 崔田雨,李天莹,王光辉,等.男男性行为者HIV非职业暴露后预防用药现状及影响因素定性研究[J].中国艾滋病性病,2023,29(3):287-290. CUI T Y,LI T Y,WANG G H,et al.Qualitative study on taking HIV non-occupational post-exposure prophylaxis and its influencing factors among men who have sex with men[J].Chin J AIDS STD,2023,29(3):287-290.(in Chinese) [14] 李传玺,林玉玺,王霖,等.艾滋病高危人群对暴露后预防使用意愿的影响因素研究[J].中国艾滋病性病,2021,27(10):1096-1101. LI C X,LIN Y X,WANG L,et al.Analysis of influencing factors of willingness to post-exposure prophylaxis among high risk populations for HIV[J].Chin J AIDS STD,2021,27(10):1096-1101.(in Chinese) [15] 姜庭意,徐园园,李昕,等.南京地区流动MSM HIV药物预防知识知晓和使用意愿调查[J].中国艾滋病性病,2023,29(12):1323-1329. JIANG T Y,XU Y Y,LI X,et al.Awareness and willingness to use HIV pre-exposure prophylaxis among MSM from the floating population in Nanjing[J].Chin J AIDS STD,2023,29(12):1323-1329.(in Chinese)
