Characteristics of malignant tumor incidence and mortality in cancer registration areas of Zhejiang Province in 2021
DU Lingbin1, QIU Yu2, LI Huizhang1, LI Runhua1, ZHU Chen1, WANG Le1, QIU Yanfei1
1. Zhejiang Cancer Hospital, Zhejiang Provincial Cancer Prevention and Control Office, Hangzhou, Zhejiang 310022, China; 2. School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China
Abstract：Objective To investigate the characteristics of malignant tumor incidence and mortality in cancer registration areas of Zhejiang Province in 2021. Methods Based on the 2021 cancer registration data from 22 national cancer registries in Zhejiang Province, the crude incidence, crude mortality, and cumulative rate for 0 to 74 years were calculated. Age standardized was performed using the age composition of the standard population from the Fifth National Population Census in 2000 and Segi's world standard population. The incidence and mortality characteristics of malignant tumor in different genders, urban/rural areas and ages were described. The order of crude incidence and mortality of malignant tumor were analyzed. Results In 2021, there were 116 639 new malignant tumor cases in Zhejiang Province. The crude, Chinese population standardized, and world population-standardized incidences were 530.93/105, 304.83/105, and 288.20/105, respectively. The cumulative incidence for 0 to 74 years was 31.92%. There were 40 475 death cases. The crude, Chinese population-standardized, and world population-standardized mortalities were 184.24/105, 79.40/105, and 78.97/105, respectively. The cumulative mortality for 0 to 74 years was 8.37%. The Chinese population-standardized incidence for males and females were 286.34/105 and 323.45/105, respectively, and the Chinese population-standardized mortality were 106.25/105 and 54.17/105, respectively. The Chinese population-standardized incidence for urban and rural were 316.85/105 and 285.11/105, respectively, and the Chinese population-standardized mortality were 75.59/105 and 85.48/105, respectively. The crude incidence and crude mortality of malignant tumor both increased with age, peaking in the groups aged 80-<80 and ≥85 years at 1 845.06/105 and 1 656.88/105, respectively. The top ten malignant tumors with the highest crude incidence were, in descending order: lung cancer, thyroid cancer, breast cancer, prostate cancer, colorectal cancer, gastric cancer, liver cancer, cervical cancer, lymphoma, and brain tumors. These accounted for 80.34% of all new malignant tumor cases. The top ten malignant tumors with the highest crude mortality were, in descending order: lung cancer, liver cancer, colorectal cancer, gastric cancer, pancreatic cancer, prostate cancer, breast cancer, esophageal cancer, lymphoma, and gallbladder cancer. These accounted for 82.26% of all malignant tumor deaths. Conclusions In 2021, the cancer registration areas of Zhejiang Province were characterized by a relatively high malignant tumor incidence and a comparatively low mortality compared to national data. Males and the elderly emerged as key populations for targeted prevention and control. It is recommended to enhance screening, early diagnosis, and early treatment for lung cancer, thyroid cancer, prostate cancer, breast cancer, and gastric cancer malignancies.
杜灵彬, 邱雨, 李辉章, 李润华, 朱陈, 王乐, 裘燕飞. 2021年浙江省肿瘤登记地区恶性肿瘤发病和死亡特征分析[J]. 预防医学, 2025, 37(10): 973-978.
DU Lingbin, QIU Yu, LI Huizhang, LI Runhua, ZHU Chen, WANG Le, QIU Yanfei. Characteristics of malignant tumor incidence and mortality in cancer registration areas of Zhejiang Province in 2021. Preventive Medicine, 2025, 37(10): 973-978.
[1] CHEN W Q,ZHENG R S,BAADE P D,et al.Cancer statistics in China,2015[J].CA Cancer J Clin,2016,66(2):115-132. [2] HAN B F,ZHENG R S,ZENG H M,et al.Cancer incidence and mortality in China,2022[J].J Natl Cancer Cent,2024,4(1):47-53. [3] 王乐,王悠清,李辉章,等.浙江省居民恶性肿瘤防治核心知识知晓水平及影响因素分析[J].预防医学,2021,33(8):757-761,767. WANG L,WANG Y Q,LI H Z,et al.Awareness of core knowledge about cancer prevention and its influencing factors among residents in Zhejiang Province[J].China Prev Med J,2021,33(8):757-761,767.(in Chinese) [4] 张思维,郑荣寿,孙可欣,等.2016年中国恶性肿瘤分地区发病和死亡估计:基于人群的肿瘤登记数据分析[J].中国肿瘤,2023,32(5):321-332. ZHANG S W,ZHENG R S,SUN K X,et al.Estimation of cancer incidence and mortality in different geographic areas of China in 2016:analysis based on population-based cancer registry data[J].China Cancer,2023,32(5):321-332.(in Chinese) [5] 程向东,杜灵彬.2024浙江省肿瘤登记年报 [M].北京:清华大学出版社,2025. CHENG X D,DU L B.Zhejiang cancer registry annual report 2024 [M].Beijing:Tsinghua University Press,2025.(in Chinese) [6] 杜灵彬. 浙江省肿瘤防控工作50余年发展历程[J].中国肿瘤,2023,32(10):747-752. DU L B.Cancer prevention and control in Zhejiang Province over the past 50 years[J].China Cancer,2023,32(10):747-752.(in Chinese) [7] LI H Z,WANG Y Q,GONG W W,et al.Cancer survival analysis on population-based cancer registry data in Zhejiang Province,China(2018-2019)[J].J Natl Cancer Cent,2023,4(1):54-62. [8] ZENG H M,ZHENG R S,SUN K X,et al.Cancer survival statistics in China 2019-2021:a multicenter,population-based study[J].J Natl Cancer Cent,2024,4(3):203-213. [9] 浙江省统计局. 2024年浙江省人口主要数据公报[EB/OL].[2025-09-28].https://tjj.zj.gov.cn/art/2025/3/1/art_1229129205_5469687.html. [10] 程向东,杜灵彬.2023浙江省肿瘤登记年报 [M].北京:清华大学出版社,2024. CHENG X D,DU L B.Zhejiang cancer registry annual report 2023 [M].Beijing:Tsinghua University Press,2024.(in Chinese) [11] 浙江省统计局.浙江统计年鉴[EB/OL].[2025-09-28].https://tjj.zj.gov.cn/col/col1525563/index.html. [12] 浙江省卫生健康委员会. 2023年浙江省15岁以上居民吸烟率结果公布[EB/OL].[2025-09-28].https://mp.weixin.qq.com/s/hc-ZqYWKHXvK0ODcrbvE9g. [13] LI N,TAN F W,CHEN W Q,et al.One-off low-dose CT for lung cancer screening in China:a multicentre,population-based,prospective cohort study[J].Lancet Respir Med,2022,10(4):378-391. [14] 朱夏燕,陶欢青,王乐,等.2021年浙江省肿瘤登记地区前列腺癌发病与死亡特征及2000—2021年变化趋势分析[J/OL].中国肿瘤,2025[2025-09-28].https://kns.cnki.net/kcms/detail/11.2859.R.20250923.1006.002.html. ZHU X Y,TAO H Q,WANG L,et al.Incidence and mortality of prostate cancer in Zhejiang cancer registration areas in2021 and trends from 2000 to 2021[J/OL].China Cancer,2025[2025-09-28].https://kns.cnki.net/kcms/detail/11.2859.R.20250923.1006.002.html.(in Chinese) [15] 和金金,朱陈,潘婷婷,等.定性和定量粪便免疫化学试验筛查结直肠癌效果评价[J].预防医学,2024,36(4):317-321. HE J J,ZHU C,PAN T T,et al.Evaluation of the effectiveness of qualitative and quantitative fecal immunochemical tests in colorectal cancer screening[J].China Prev Med J,2024,36(4):317-321.(in Chinese) [16] 黄文雯,李辉章,陈刚,等.浙江省2019年至2021年上消化道癌机会性筛查结果分析[J].中国肿瘤临床,2023,50(7):356-362. HUANG W W,LI H Z,CHEN G,et al.Analysis of opportunistic screening of upper gastrointestinal cancer in Zhejiang Province in 2019-2021[J].Chin J Clin Oncol,2023,50(7):356-362.(in Chinese) [17] 浙江省疾病预防控制中心.浙江省人群乙肝表面抗原流行率持续下降[EB/OL].[2025-09-28].http://www.cdc.zj.cn/jkjl/mtfb/202208/t20220819_1269.shtml.
