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预防医学  2022, Vol. 34 Issue (7): 715-719,726    DOI: 10.19485/j.cnki.issn2096-5087.2022.07.014
  疾病监测 本期目录 | 过刊浏览 | 高级检索 |
张家港市40岁及以上人群慢性阻塞性肺疾病合并骨质疏松症筛查结果
沈腊梅1, 王临池1, 杜国明2, 张钧1, 邱晶2, 朱晓炜2, 陆艳1
1.苏州市疾病预防控制中心慢性病防制科,江苏 苏州 215004;
2.张家港市疾病预防控制中心,江苏 张家港 215600
Prevalence of comorbid chronic obstructive pulmonary disease and osteoporosis among residents aged 40 years and older in Zhangjiagang City
SHEN Lamei1, WANG Linchi1, DU Guoming2, ZHANG Jun1, QIU Jing2, ZHU Xiaowei2, LU Yan1
1. Department of Chronic Disease Control, Suzhou Center for Disease Control and Prevention, Suzhou, Jiangsu 215004, China;
2. Zhangjiagang Center for Disease Control and Prevention, Zhangjiagang, Jiangsu 215600, China
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摘要 目的 了解江苏省张家港市40岁及以上人群慢性阻塞性肺疾病(COPD)合并骨质疏松症(OP)情况,并分析影响因素,为预防COPD合并OP提供依据。方法 于2019年采用多阶段分层整群随机抽样方法,抽取张家港市≥40岁常住居民为筛查对象,进行肺功能检查和骨密度检测,描述COPD合并OP检出情况;收集筛查对象人口学信息、吸烟、饮食、锻炼及体格检查资料,采用logistic回归模型分析COPD合并OP的影响因素。结果 纳入3 140人,年龄为(62.89±9.13)岁;男性1 315人,占41.88%;女性1 825人,占58.12%。检出COPD合并OP 137例,占4.36%。单纯COPD患者肺功能分级分别为轻度19例,中度133例,重度87例,极重度26例;COPD合并OP患者分别为轻度10例,中度56例,重度56例,极重度15例;COPD合并OP患者肺功能分级严重程度高于单纯COPD患者(Z=-12.304,P<0.001)。多因素logistic回归分析结果显示,≥65岁(OR=2.703,95%CI:1.862~3.923)、女性(OR=2.897,95%CI:1.915~4.384)和体力劳动职业(OR=1.540,95%CI:1.083~2.189)是COPD合并OP的影响因素。结论 张家港市40岁及以上人群中COPD合并OP患者占4.36%,肺功能分级以中重度为主;老年人、女性和体力劳动职业人群COPD合并OP患病风险较高。
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沈腊梅
王临池
杜国明
张钧
邱晶
朱晓炜
陆艳
关键词 慢性阻塞性肺疾病骨质疏松症合并症    
AbstractObjective To investigate the prevalence of comorbid chronic obstructive pulmonary disease (COPD) and osteoporosis (OP) and its influencing factors among residents aged 40 years and older in Zhangjiagang City, Jiangsu Province, so as to provide insights into prevention of comorbid COPD and OP. Methods Permanent residents aged 40 years and older were sampled using a multi-stage stratified cluster random sampling method in Zhangjiagang City in 2019, and their pulmonary functions and bone mineral density were measured. The prevalence of comorbid COPD with OP was estimated. The demographic features, smoking, diet, exercises and physical examinations were collected, and factors affecting the prevalence of comorbid COPD with OP were identified using a logistic regression model. Results Totally 3 140 subjects were enrolled, including 1 315 men (41.88%) and 1 825 women (58.12%), and a mean age of (62.89±9.13) years. A total of 137 subjects were detected with comorbid COPD and OP, with prevalence of 4.36%. The patients with COPD alone included 19 cases with mild, 133 cases with moderate, 87 cases with severe and 26 cases with very severe COPD, and the patients with comorbid COPD and OP included 10 cases with mild, 56 cases with moderate, 56 cases with severe and 15 cases with very severe COPD. The grade of pulmonary functions was higher in patients with comorbid COPD and OP than in patients with COPD alone (Z=-12.304, P<0.001). Multivariable logistic regression analysis identified ages of 65 years and older (OR=2.703, 95%CI: 1.862-3.923), women (OR=2.897, 95%CI: 1.915-4.384) and physical labor (OR=1.540, 95%CI: 1.083-2.189) as factors affecting the development of comorbid COPD and OP. Conclusion The prevalence of comorbid COPD and OP was 4.36% among residents at ages of 40 years and older in Zhangjiagang City, and moderate and severe degree was the predominant grade of pulmonary functions. The elderly, women and physical labors are at a high risk of developing comorbid COPD and OP.
Key wordschronic obstructive pulmonary disease    osteoporosis    comorbidity
收稿日期: 2022-03-09      修回日期: 2022-05-21      出版日期: 2022-07-10
中图分类号:  R181.3  
基金资助:江苏省科技计划(BE2019674); 苏州市卫生科技项目(GWZX201905); 苏州市科技局项目(SS201807,SYS2018098,SYS2020197); 江苏省预防医学课题(Y2018032); 姑苏卫生人才计划培养项目(GSWS2020098)
通信作者: 陆艳,E-mail:673261024@qq.com   
作者简介: 沈腊梅,本科,主管医师,主要从事慢性病流行病学研究工作
引用本文:   
沈腊梅, 王临池, 杜国明, 张钧, 邱晶, 朱晓炜, 陆艳. 张家港市40岁及以上人群慢性阻塞性肺疾病合并骨质疏松症筛查结果[J]. 预防医学, 2022, 34(7): 715-719,726.
SHEN Lamei, WANG Linchi, DU Guoming, ZHANG Jun, QIU Jing, ZHU Xiaowei, LU Yan. Prevalence of comorbid chronic obstructive pulmonary disease and osteoporosis among residents aged 40 years and older in Zhangjiagang City. Preventive Medicine, 2022, 34(7): 715-719,726.
链接本文:  
http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2022.07.014      或      http://www.zjyfyxzz.com/CN/Y2022/V34/I7/715
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