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预防医学  2022, Vol. 34 Issue (2): 129-134    DOI: 10.19485/j.cnki.issn2096-5087.2022.02.005
  论著 本期目录 | 过刊浏览 | 高级检索 |
肥胖和中心性肥胖对高血压的交互作用分析
王亮亮, 黄瑜, 郭伟, 魏兴民, 范宁, 赵贵雪, 颉亚辉, 马东京, 王云超, 王新华, 吴建军
甘肃中医药大学公共卫生学院,甘肃 兰州 730000
Interaction between obesity/central obesity and hypertension
WANG Liangliang, HUANG Yu, GUO Wei, WEI Xingmin, FAN Ning, ZHAO Guixue, XIE Yahui, MA Dongjing, WANG Yunchao, WANG Xinhua, WU Jianjun
School of Public Health, Gansu University of Traditional Chinese Medicine, Lanzhou, Gansu 730000, China
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摘要 目的 分析肥胖和中心性肥胖对高血压患病影响的交互作用,为制定高血压防控措施提供依据。方法 于2018年9—12月,采用多阶段随机抽样方法抽取甘肃省白银市白银区35~75岁居民进行问卷调查和体格检查;采用logistic回归模型分析肥胖与中心性肥胖对高血压影响的交互作用,采用ANDERSSON等编制的Excel表计算交互作用指数(SI)、相对超额危险度比(RERI)和归因比(AP)等交互作用指标。结果 发放调查问卷6 246份,回收有效问卷6 169份,回收有效率为98.77%。调查男性3 038人,占49.25%;女性3 131人,占50.75%。年龄为(52.05±8.78)岁。检出肥胖832例,占13.49%;中心性肥胖2 278例,占36.93%。高血压粗患病率为35.89%,标化患病率为33.05%。多因素logistic回归分析结果显示,肥胖(OR=2.020, 95%CI: 1.705~2.393)和中心性肥胖(OR=1.622,95%CI:1.433~1.836)与高血压患病均有统计学关联;肥胖和中心性肥胖对高血压患病的影响不存在相乘交互作用(OR=1.011,95%CI:0.655~1.560),也不存在相加交互作用(SI=1.405,95%CI:0.815~2.424;RERI=0.658,95%CI:-0.298~1.614;AP=0.201,95%CI:-0.075~0.476)。结论 肥胖和中心性肥胖增加高血压患病风险,但未发现两者存在交互作用。
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王亮亮
黄瑜
郭伟
魏兴民
范宁
赵贵雪
颉亚辉
马东京
王云超
王新华
吴建军
关键词 高血压肥胖中心性肥胖交互作用    
AbstractObjective To examine the effects of obesity and central obesity on hypertension, so as to provide insights into the prevention and control measures of hypertension. Methods From September to December 2018, residents at ages of 35 to 75 years were sampled using the multi-stage random sampling method in Baiyin District, Baiyin City, Gansu Province, and subjected to questionnaire surveys and physical examinations. The interaction between obesity/central obesity and hypertension was evaluated using logistic regression analysis. The synergy index ( SI ), relative excess risk due to interaction ( RERI ) and attributable proportion due to interaction ( AP ) were calculated using Excel compiled by Andersson et al. Results A total of 6 246 questionnaires were allocated and 6 169 valid questionnaires were recovered, with an effective recovery rate of 98.77%. The respondents included 3 038 men ( 49.25% ) and 3 131 women (50.75%), with a mean age of ( 52.05±8.78 ) years. There were 832 respondents with obesity ( 13.49% ) and 2 278 with central obesity ( 36.93% ). The crude and standardized prevalence rates of hypertension were 35.89% and 33.05%, respectively. Multivariable logistic regression analysis showed that obesity ( OR=2.020, 95%CI: 1.705-2.393 ) and central obesity ( OR=1.622, 95%CI: 1.433-1.836 ) were statistically associated with hypertension. There was no multiplicative interaction between obesity or central obesity and hypertension ( OR=1.011, 95%CI: 0.655-1.560 ), and no additive interaction was detected between obesity or central obesityand hypertension ( SI=1.405, 95%CI: 0.815-2.424; RERI=0.658, 95%CI: -0.298 to 1.614; AP=0.201, 95%CI: -0.075 to 0.476 ). Conclusions Obesity and central obesity increase the risk of hypertension; however, no interaction is detected between obesity or central obesity and hypertension.
Key wordshypertension    obesity    central obesity    interaction
收稿日期: 2021-09-27      修回日期: 2021-12-11      出版日期: 2022-02-10
中图分类号:  R544.1  
基金资助:甘肃省卫健委卫生健康管理项目(31340301); 甘肃省重大疾病分子医学与中医药防治研究重点实验室新型冠状病毒防治研究专项(FZYX20-13); 甘肃省高等学校产业支撑计划项目(2020C-36)
通信作者: 吴建军,E-mail:wjj@gszy.edu.cn;王新华,E-mail:Wangxinhua@163.com   
作者简介: 王亮亮,硕士在读
引用本文:   
王亮亮, 黄瑜, 郭伟, 魏兴民, 范宁, 赵贵雪, 颉亚辉, 马东京, 王云超, 王新华, 吴建军. 肥胖和中心性肥胖对高血压的交互作用分析[J]. 预防医学, 2022, 34(2): 129-134.
WANG Liangliang, HUANG Yu, GUO Wei, WEI Xingmin, FAN Ning, ZHAO Guixue, XIE Yahui, MA Dongjing, WANG Yunchao, WANG Xinhua, WU Jianjun. Interaction between obesity/central obesity and hypertension. Preventive Medicine, 2022, 34(2): 129-134.
链接本文:  
http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2022.02.005      或      http://www.zjyfyxzz.com/CN/Y2022/V34/I2/129
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