Please wait a minute...
文章检索
预防医学  2021, Vol. 33 Issue (5): 442-445    DOI: 10.19485/j.cnki.issn2096-5087.2021.05.003
  论著 本期目录 | 过刊浏览 | 高级检索 |
河南省蔬菜水果双酚S污染的居民膳食暴露风险评估
刘红丽, 马青青, 卢素格, 翟志雷, 张二鹏, 张榕杰
河南省疾病预防控制中心检测检验中心理化室,河南 郑州 450016
Dietary exposure risk of bisphenol S in vegetables and fruits inHenan Province
LIU Hongli, MA Qingqing, LU Suge, ZHAI Zhilei, ZHANG Erpeng, ZHANG Rongjie
Department of Physics and Chemistry, Testing Center, Henan Center for Disease Control and Prevention, Zhengzhou, Henan 450016, China
全文: PDF(1564 KB)  
输出: BibTeX | EndNote (RIS)      
摘要 目的 分析河南省蔬菜水果双酚S(BPS)污染水平,并评估居民膳食暴露风险,为制订相关的食品安全标准提供依据。方法 于2018—2019年采集河南省本地种植、销售的蔬菜水果样品276份,采用同位素稀释-超高效液相色谱-三重四极杆串联质谱法(UPLC-MS/MS)测定BPS;结合当地居民的膳食结构和平均体重计算膳食暴露量,参考类似物双酚A(BPA)的每日耐受摄入量(TDI)计算BPS的风险指数。结果 蔬菜和水果中检出BPS含量分别为0.006~12.600 µg/kg和0.006~9.380 µg/kg,中位数分别为0.053 µg/kg和0.023 µg/kg,检出率分别为78.43%和62.60%,蔬菜BPS检出率和含量均大于水果(P<0.05)。居民来源于蔬菜水果的BPS最大暴露总量为5.37×10-2 µg/(kg体重·d),暴露风险指数为1.07×10-3,风险可接受。结论 河南省蔬菜和水果中均检出BPS,蔬菜中BPS的检出率和含量均大于水果。居民经蔬菜水果暴露BPS的健康风险较小。
服务
把本文推荐给朋友
加入引用管理器
E-mail Alert
RSS
作者相关文章
刘红丽
马青青
卢素格
翟志雷
张二鹏
张榕杰
关键词 蔬菜水果双酚S膳食暴露风险    
AbstractObjective To monitor the content of bisphenol S ( BPS ) in vegetables and fruits in Henan Province and evaluate the dietary exposure risk of the population, so as to provide the basis for formulating relevant food safety standards. Methods From 2018 to 2019, 276 samples of vegetables and fruits produced and sold in Henan Province were collected. BPS was determined by isotope dilution ultra performance liquid chromatography triple quadrupole tandem mass spectrometry ( UPLC-MS/MS ) , and the dietary exposure was calculated according to the dietary structure and average body weight of local residents. The risk index of BPS was calculated according to the daily tolerable intake ( TDI ) of bisphenol A ( BPA ). Results The BPS contents in vegetables and fruits were 0.006-12.600 µg/kg and 0.006-9.380 µg/kg, the medians were 0.053 µg/kg and 0.023 µg/kg, the detection rates were 78.43% and 62.60%, respectively.The detection rate and content of BPS in vegetables were higher than those in fruits ( P<0.05 ). The maximum exposure of BPS from vegetables and fruits was 5.37×10-2 µg/ ( kgbw·d ), and the exposure risk index was 1.07 × 10-3, which was acceptable. Conclusions BPS was detected from vegetables and fruits in Henan Province. The detection rate and content of BPS in vegetables were higher than those in fruits. The health risk of BPS exposed by vegetables and fruits is small.
Key wordsvegetable    fruit    bisphenol S    dietary exposure risk
收稿日期: 2021-02-19      修回日期: 2021-03-15      出版日期: 2021-05-10
中图分类号:  R155.5  
基金资助:河南省医学科技攻关计划省部共建项目(2018010030)
通信作者: 张榕杰,E-mail:13903868287@163.com   
作者简介: 刘红丽,本科,副主任技师,主要从事食品卫生理化检验工作
引用本文:   
刘红丽, 马青青, 卢素格, 翟志雷, 张二鹏, 张榕杰. 河南省蔬菜水果双酚S污染的居民膳食暴露风险评估[J]. 预防医学, 2021, 33(5): 442-445.
LIU Hongli, MA Qingqing, LU Suge, ZHAI Zhilei, ZHANG Erpeng, ZHANG Rongjie. Dietary exposure risk of bisphenol S in vegetables and fruits inHenan Province. Preventive Medicine, 2021, 33(5): 442-445.
链接本文:  
http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2021.05.003      或      http://www.zjyfyxzz.com/CN/Y2021/V33/I5/442
[1] 陈小芳,李东,固旭.双酚类化合物的合成及应用进展研究[J].广州化工,2016,44(5):26-28.
[2] 李金荣,郭瑞昕,刘艳华,等.五种典型环境内分泌干扰物赋存及风险评估的研究进展[J].环境化学,2020,39(10):2637-2653.
[3] 王蔚,王子豪,张晓娜.双酚A及其类似物对哺乳动物和鱼类神经毒性效应及机制研究进展[J].中国海洋大学学报,2019,49(5):27-34.
[4] ELADAK S,MOISON D,GUERQUIN M J,et al.Effects of environmental bisphenol A exposures on germ cell development and leydig cell function in the human fetal testis[J].PLoS One,2018,13(1):e191934.
[5] HERCOG K,MAISANABA S,FILIPIC M,et al.Genotoxic activity of bisphenol A and its analogues bisphenol S,bisphenol F and bisphenol AF and their mixtures in human hepatocellular carcinoma(HepG2)cells[J].Science of the Total Environment,2019,687:267-276.
[6] 廖爱玲,吴鹏.欧盟今日起禁止生产含双酚A塑料奶瓶[N].新京报,2011-03-01(1).
[7] 卫生部等6部门关于禁止双酚A用于婴幼儿奶瓶的公告.卫生部公告.2011年第15号[EB/OL].[2021-03-15].http://www.moh.gov.cn/mohwsjdj/s7891/201105/51866.shtml.
[8] 沈杰,刘建超,陆光华,等.双酚S和双酚F在水环境中的分布、毒理效应及其生态风险研究进展[J].生态毒理学报,2018,13(5):40-51.
[9] 陈金,王晓南,李霁,等.太湖流域双酚AF和双酚S人体健康水质基准的研究[J].环境科学学报,2019,39(8):2764-2770.
[10] 宋淑玲,马生明.双酚S毒理学、人体暴露水平与健康效应研究进展[J].环境化学,2018,37(2):200-208.
[11] CHEN D,KANNAN K,TAN H,et al.Bisphenol analogues other than BPA:environmental occurrence,human exposure,and toxicity-A review[J].Environ Sc Technol,2016,50(11):5438-5453.
[12] DONG X,ZHANG Z,MENG S,et al.Parental exposure to bisphenol A and its analogs influences zebrafish offspring immunity[J].Sci Total Environ,2017,610:291-297.
[13] 裘文慧. 双酚A及其替代物双酚S对鱼类免疫和神经内分泌系统的毒性效应与作用机理[D].上海:上海大学,2016.
[14] WU L H,ZHANG X M,WANG F,et al.Occurrence of bisphenol S in the environment and implications for human exposure:a short review[J].Sci Total Environ,2017,615:87-98.
[15] 中华人民共和国国家卫生和计划生育委员会,国家食品药品监督管理总局.食品安全国家标准食品中污染物限量:GB 2762—2017[S].北京:中国标准出版社,2017.
[16] 周昇昇,高莉,孙经,等.河南省盐摄入与高血压调查[J].中华高血压杂志,2020,28(11):1045-1050.
[17] GOETZ N V,WORMUTH M,SCHERINGER M,et al.Bisphenol A: how the most relevant exposure sources contribute to total consumer exposure[J].Risk Anal,2010,30(3):473-487.
[18] 张磊,刘兆平.食品化学物风险评估中一些重要参数的选择和使用[J].中国食品卫生杂志,2015,27(3):308-311.
[19] 于洋. 蔬菜常用农药环境风险评估及控制策略研究[D].沈阳:沈阳农业大学,2018.
[20] 胡雅琪. 再生水灌溉典型雌激素类内分泌干扰物的环境行为与风险防控阈值[D].北京:中国水利水电科学研究院,2019.
[21] 徐秋桐. 土壤-蔬菜系统典型污染物的污染特征及抗生素的生理效应[D].杭州:浙江大学,2019.
[22] 裴小乐. 河南省农膜污染现状及治理对策思考[D].郑州:河南农业大学,2018.
[23] 中国营养学会.中国居民膳食指南(2016)[M].北京:人民卫生出版社,2016.
[1] 宋韶芳, 张维蔚, 张玉华, 王燕燕, 曾锦衡, 潘心红. 广州市21种市售蔬菜新烟碱类杀虫剂膳食风险评估[J]. 预防医学, 2023, 35(9): 781-785.
[2] 许娇娇, 蔡增轩, 王军淋, 徐美佳, 黄百芬. 新鲜水果真菌毒素多组分检测方法研究[J]. 预防医学, 2022, 34(6): 555-560.
[3] 姚建花, 邵国健, 胡明友, 徐玲珍, 余娟. 改进的QuEChERS结合GC-MS/MS测定叶菜类蔬菜14种有机氯和拟除虫菊酯类农药残留[J]. 预防医学, 2021, 33(8): 859-862.
[4] 徐映如, 陈道湧, 沈俊毅, 张颖琦. 虹口区市售蔬菜重金属污染与健康风险评估[J]. 预防医学, 2021, 33(4): 406-410.
[5] 郭蓉, 王玮, 刘存卫, 程国霞, 胡佳薇, 王彩霞, 田丽, 李天来. 陕西省部分蔬菜中有机磷农药残留的膳食暴露风险评估[J]. 预防医学, 2018, 30(2): 148-152.
[6] 高何刚,杜赛,王瑞,王晶. 超高效液相色谱-串联质谱法同时测定水果中杀菌剂和植物生长调节剂[J]. 预防医学, 2017, 29(10): 1074-1077.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed