Abstract:Objective To learn the relationship between chronic complications of type 2 diabetic and stroke incidence.Methods Based on the surveillance data of type 2 diabetes and stroke in Xiuzhou district of Jiaxing City from 2009 to 2014, using logistic regression model method to analysis the relationships between chronic complications of type 2 diabetic and stroke incidence.Results Among 6 108 participants, 462 subjects developed stroke (7.56%); 479 (7.84%) diabetes patients were diagnosed with chronic complications simultaneously and 116 subjects developed stroke (24.21%), higher than those no chronic complications (6.15%, P<0.05). The proportion of diabetic vasculopathy, nephropathy, neuropathy, retinopathy and skin infection were 33.33%, 24.64%, 23.23%, 13.48% and 5.32%, respectively. After adjusted for gender, age, occupation, urban and rural, obesity, hypertension and hyperlipidemia, there were significant statistical correlations between vasculopathy, neuropathy and stroke, the OR values and 95%CI were 4.95(3.41-7.19) and 2.79(1.80-4.32);patients who combined with any one,two, three or more chronic complications were significantly associated with the onset of stroke when compared with those without chronic complication, the OR values were 1.28, 2.75 and 5.38, respectivelyConclusion Vasculopathy and neuropathy of type 2 diabetes patients which found at diagnosed were risk factors of stroke,and the more for type 2 diabetes patients combined with the chronic complications, the greater the risk of stroke.
朱秋荣, 徐惠庆, 骆田斌, 余梦华. 2型糖尿病患者慢性并发症与脑卒中发病的关系[J]. 预防医学, 2017, 29(4): 351-354.
ZHU Qiu-rong, XU Hui-qing, LUO Tian-bin, YU Meng-hua. A study on the relationship between chronic complications of type 2 diabetic and stroke incidence. Preventive Medicine, 2017, 29(4): 351-354.
[1]NING G, BLOOMGARDEN Z. Diabetes in China: prevalence, diagnosis, and control [J]. J Diabetes, 2013, 5(4):372. [2]MATTHEWS D R, MATTHEWS P C. Banting Memorial Lecture: reply from Matthews and Matthews. Type 2 diabetes as an ' infectious disease: is this the Black Death of the 21st century?[J]. Diabet Med, 2011, 28(7): 880. [3]中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2010年版)[J]. 中国医学前沿杂志(电子版), 2011,20 (6):1227-1245. [4]FONVILLE S, ZANDBERGEN A A, VERMEER S E, et al. Prevalence of prediabetes and newly diagnosed diabetes in patients with a transient ischemic attack or stroke[J]. Cerebrovasc Dis,2013, 36(4): 283-289. [5]KAMALESH M, SHEN J, ECKERT G J. Long term postischemic stroke mortality in diabetes: a veteran cohort analysis [J]. Stroke, 2008, 39(10): 2727-2731. [6]ALLEN N B, HOLFORD T R, BRACKEN M B, et al. Geographic variation in one-year recurrent ischemic stroke rates for elderly Medicare beneficiaries in the USA [J]. Neuroepidemiology, 2010, 34(2): 123-129. [7]LO S F, CHU S W, MUO C H, et al. Diabetes mellitus and accompanying hyperlipidemia are independent risk factors for adhesive capsulitis: a nationwide population-based cohort study(version 2)[J]. Rheumatol Int, 2014, 34(1): 67-74. [8]中华医学会神经病学分会脑血管病学组急性缺血性脑卒中诊治指南撰写组. 中国急性缺血性脑卒中诊治指南2010[J]. 中华神经科杂志,2010,43(2):146-153. [9]陈春明, 孔灵芝. 中国成人超重和肥胖症预防控制指南[M]. 北京: 人民卫生出版社, 2006: 1-35. [10]American Diabetes Association. Standards of Medical Care in Diabetes-2014[J]. Diabetes Care, 2014, 37(suppl 1):S14-S80. [11]ACCORD STUDY GROUP, CUSHMAN W C, EVANS G W, et al. Effects of intensive blood-pressure control in type 2 diabetes mellitus [J]. N Engl J Med, 2010, 362(17): 1575-1585. [12]UDELL J A, SCIRICA B M, BRAUNWALD E, et al. statin and aspirin therapy for the prevention of cardiovascular events in patients with type 2 diabetes mellitus [J]. Clin Cardiol, 2012, 35(12): 722-729. [13]GREGG E W, LI Y, WANG J, et al. Changes in diabetes-related complications in the United States, 1990-2010[J]. N Engl J Med, 2014, 370(16): 1514-1523. [14]TAM V H, LAM E P, CHU B C, et al. Incidence and progression of diabetic retinopathy in Hong Kong Chinese with type 2 diabetes mellitus [J]. J Diabetes Complicat, 2009, 23(3): 185-193. [15]邵永强. 社区人群糖尿病患病率及危险因素研究[J]. 浙江预防医学, 2011, 23(2): 3-6. [16]张雪冰, 母义明, 李洪梅. 2型糖尿病与缺血性脑卒中[J]. 中华临床医师杂志(电子版), 2015, 9(12): 103-106. [17]ZHUO L, ZOU G, LI W, et al. Prevalence of diabetic nephropathy complicating non-diabetic renal disease among Chinese patients with type 2 diabetes mellitus[J]. Eur J Med Res, 2013, 18(1): 4. [18]陆艳艳. 肥胖型2型糖尿病与脑血管病变的相关性研究[D]. 苏州:苏州大学,2014. [19]KANNO A, KIKUYA M, OHKUBO T, et al. Pre-hypertension as a significant predictor of chronic kidney disease in a general population: the Ohasama Study[J]. Nephrol Dial Transplant, 2012,27(8): 3218-3223. [20]LIM C C, TEO B W, ONG P G, et al. Chronic kidney disease, cardiovascular disease and mortality: A prospective cohort study in a multi-ethnic Asian population[J]. Eur J Prev Cardiol, 2015, 22(8):1018-1026. [21]纪立农. 对2型糖尿病新的大型临床试验结果的解读和分析[J]. 中国糖尿病杂志, 2008,16(11):642-647. [22]潘劲,胡如英,龚巍巍,等. 浙江省2007至2012年糖尿病流行特征的描述性分析[J].中华内分泌代谢杂志, 2015, 31(10): 846-850.