Abstract:Objective To investigate the trend in mortality of esophageal cancer in Wenzhou City, Zhejiang Province from 2015 to 2025, so as to provide the basis for improving prevention and control strategies of esophageal cancer. Methods Data on esophageal cancer deaths in Wenzhou City from 2015 to 2025 were collected through the Wenzhou Chronic Disease Collaborative Management System. The crude mortality was calculated. The Chinese population-standardized mortality was calculated based on the data from the Fifth National Population Census of China in 2000, while the world population-standardized mortality was calculated using Segi's world standard population data. A Joinpoint regression model was used to analyze the trend in mortality of esophageal cancer by gender, urban/rural areas, and age group. Results A total of 6 978 esophageal cancer deaths were reported in Wenzhou City from 2015 to 2025, including 6 090 males (87.27%) and 888 females (12.73%). From 2015 to 2025, the crude mortality, Chinese population-standardized mortality and world population-standardized mortality of esophageal cancer in Wenzhou City were 7.68/105, 4.12/105 and 4.16/105, respectively, showing downward trends (AAPC=-2.533%, -6.486% and -6.235%, all P<0.05). The crude mortality (P<0.05), Chinese population-standardized mortality and world population-standardized mortality of esophageal cancer in males were higher than in females. From 2015 to 2025, the crude mortality (AAPC=-2.090%, -5.103%), Chinese population-standardized mortality (AAPC=-5.819%, -9.868%) and world population-standardized mortality (AAPC=-5.780%, -9.432%) of esophageal cancer among males and females showed downward trends (all P<0.05). The crude mortality (P<0.05), Chinese population-standardized mortality and world population-standardized mortality of esophageal cancer in urban areas were higher than in rural areas. From 2015 to 2025, the crude mortality (AAPC=-3.635%, -2.198%), Chinese population-standardized mortality (AAPC=-7.151%, -6.131%) and world population-standardized mortality (AAPC=-7.123%, -6.051%) of esophageal cancer in urban and rural areas showed downward trends (all P<0.05). The crude mortality of esophageal cancer increased with age (P<0.05), and peaked in the 80-<85 years age group, at 58.15/105. From 2015 to 2025, the crude mortality of esophageal cancer in the groups aged 15-<45 years, 45-<65 years and ≥65 years in Wenzhou City showed downward trends (AAPC=-20.964%, -8.164% and -4.270%, all P<0.05). Conclusions Mortality of esophageal cancer showed a downward trend in Wenzhou City from 2015 to 2025. Males, urban residents and the elderly should be identified as priority populations for esophageal cancer prevention and control.
陈晟, 叶振淼, 郑宇航, 夏喆铮. 2015—2025年温州市食管癌死亡趋势分析[J]. 预防医学, 2026, 38(10): 996-1001.
CHEN Sheng, YE Zhenmiao, ZHENG Yuhang, XIA Zhezheng. Trend in mortality of esophageal cancer in Wenzhou City from 2015 to 2025. Preventive Medicine, 2026, 38(10): 996-1001.