Abstract：ObjectiveTo learn the main pathogenic microorganisms,and to acquire the data of pathogens composition and drug resistance of infant diarrhea disease in Wenzhou City.MethodsThe diarrheal stool specimens of < 5 years old children were collected from outpatients and inpatients in children's hospital and were cultured and detected.ResultsA total of 201 strains pathogenic bacteria were separated from 517 clinical specimens,and the rate of total detection is 38.88%,of which included 74 strains intestinal pathogenic bacteria and 127 strains diarrhea virus,with the rate of detection 14.31% and 24.56%,respectively.Among intestinal pathogenic bacteria,the E.coli was the most common bacteria(36 strains,48.65%),followed by salmonella(31 strains,41.89%).Diarrhea virus included norovirus type 2(56 strains,44.09%),norovirus type 1(24 strains,18.90%),A group rotavirus (56 strains,31.50%)and goblet virus(7 strains,5.51%).The resistance rate of Salmonella to ampicillin was 64.52%,and that to ampicillin,tetracycline,compound new Ming were more than 70.00%.The resistance rate of Rifampicin.Novobiocin in all bacteria reached 100%.ConclusionE.coli and salmonella epidemic strains were the common pathogenic bacteria in infectious diarrhea among infants in Wenzhou City.The predominant viruses were norovirus and rotavirus group A.The drug resistance of various pathogenic bacteria was different,and active surveillance should be strengthened.
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