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预防医学  2016, Vol. 28 Issue (11): 1119-1122    
  论著 本期目录 | 过刊浏览 | 高级检索 |
老年人脉压差与认知功能的关系研究
应旭华1, 李松涛1, 翟羽佳2, 尚晓鹏2, 何凡2, 沈伟2
1.玉环县疾病预防控制中心,浙江玉环317600;
2.浙江省疾病预防控制中心
A study on the association between pulse blood pressure and cognitive function among the elders in Yuhuan County of Zhejiang Province
YING Xu-hua, LI Song-tao, ZHAI Yu-jia, SHANG Xiao-peng, HE Fan, SHEN Wei
The Center for Disease Control and Prevention of Zhejiang Province, Taizhou, Zhejiang, 317600, China
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摘要 目的 研究玉环县≥60岁老年人群脉压差与认知功能的关系。方法 采用随机整群抽样方法,在玉环县随机抽取1 700名≥60岁的常住老年人,采用简易精神状态检查量表(MMSE)对其进行认知损伤筛查,采用局部加权回归散点平滑法分析脉压差与MMSE得分之间的线性关系,采用多因素Logistic回归分析脉压差与认知功能的关系。结果 共回收有效问卷1 633份,回收率为96.06%。玉环县≥60岁老年人MMSE得分平均为(23.59±5.92)分,认知损伤率为15.74%,认知损伤组脉压差为(64.01±16.31)mmHg,高于非认知损伤组的(58.97±14.67)mmHg(P<0.01)。局部加权回归散点平滑图显示,随着脉压差不断增大,老年人MMSE得分呈下降趋势。多因素Logistic回归分析显示,在调整部分协变量之后,老年人脉压差与认知功能存在统计关联(OR=1.010, 95% CI:1.001~1.019)。结论 玉环县≥60岁老年人脉压差与认知功能呈负相关,脉压差越高,认知功能表现可能越差。
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应旭华
李松涛
翟羽佳
尚晓鹏
何凡
沈伟
关键词 认知功能脉压差老年人    
AbstractObjective To explore the relationship between pulse blood pressure and cognitive function for the elders in Yuhuan County, Zhejiang Province.Methods Multi-stage cluster method was used to select 1 700 residents aged over 60 years in Yuhuan County, Zhejiang Province. Mini-Mental State Examination (MMSE) was used to screen cognitive impairment. Locally weighted scatter plot smoothing was used to explore the local linear trend between MMSE score and diastolic. The association between pulse pressure or blood pressure and cognitive function was analyzed by multivariate logistic regression analysis.Results The prevalence of cognitive impairments for the elders aged over 60 years in Yuhuan County was 15.74%. There was significant difference between the pulse blood pressure of cognitive impairment group (64.01±16.31) mmHg and none-cognitive impairment group (58.97±14.67) mmHg.The t value was 4.97. Pulse blood pressure and the elderly MMSE score showed a significant positive correlation. Multivariate logistic regression analysis showed that cognitive function related to diastolic blood pressure (OR= 1.010, 95% CI1.001-1.019,P=0.034) after adjusting several covariate.Conclusion Normal cognitive function was associated with decreased pulse blood pressure among the elders aged over 60 years in Yunhuan County, Zhejiang Province.
Key wordsCognitive function    Pulse blood pressure    Elderly
收稿日期: 2016-05-13          
中图分类号:  R544.1  
通信作者: 沈伟,E-mailwshen@cdc.zj.cn   
作者简介: 应旭华,本科,副主任医师,主要从事疾病控制与管理工作
引用本文:   
应旭华, 李松涛, 翟羽佳, 尚晓鹏, 何凡, 沈伟. 老年人脉压差与认知功能的关系研究[J]. 预防医学, 2016, 28(11): 1119-1122.
YING Xu-hua, LI Song-tao, ZHAI Yu-jia, SHANG Xiao-peng, HE Fan, SHEN Wei. A study on the association between pulse blood pressure and cognitive function among the elders in Yuhuan County of Zhejiang Province. Preventive Medicine, 2016, 28(11): 1119-1122.
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http://www.zjyfyxzz.com/CN/      或      http://www.zjyfyxzz.com/CN/Y2016/V28/I11/1119
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